Alba Announces Phase Iib Testing Of At-1001

[ENF]

Alba Therapeutics has announced that they have dosed it's first patient in a six week Phase IIb trial with oral AT-1001. See the Wed., Sept. 19, 2007 item:

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[Lisa]

That was interesting. They refer to AT-1001 as a "Treatment" for Celiac.

[Ridgewalker]

They also said that there currently is no treatment for Celiac. Then they said the only treatment is a life-long gluten-free diet, which puts "some" Celiacs in remission. I would say it works for most, wouldn't you?

[tom]

I was surprised while reading this recent article on AT-1001.

https://www.celiac.com/st_prod.html?p_prodid=1514

To me, it's very clear that the drug treats leaky-gut, not celiac.

The only way they can be thought of as clinically equivalent is if it were 100% IMPOSSIBLE to have ANY adverse effect from celiac while the intestinal wall's permeability is 'normal'.

It seems unlikely to me, tho I admit I have nowhere near the depth of knowledge to debate it w/ a Dr @ Alba.

BUT!!! . .. .. ..if it *were* true, why isn't it publicized to the point that every celiac is aware of it and taking steps to treat leaky-gut. Yes, some or many are aware, but if the drug's celiac "treatment" is entirely leaky-gut related, shouldn't it be at least as well-known as the fact that rye has a harmful gluten?