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Is This Enough For A Diagnoses?


ANDOBEAR

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ANDOBEAR Apprentice

I had a biopsy done and the nurse practitioner at my gastrointerologist suspects celiac based on my symptoms and the results. She did order the blood test just for correlation. The results of the blood tests are not in yet but this is what the biopsy report says

1. DUODENAL BIOPSY

- DUODENAL MUCOSA WITH FOCALLY INCREASED INTRAEPITHELIAL LYMPHOCYTES AT THE VILLOUS TIP AND UNDERLYING LYMPHOID FOLLICLE.

- THESE CHANGES, ALTHOUGH NON-SPECIFIC, HAVE BEEN ASSOCIATED WITH CELIAC DISEASE. CLINICAL CORRELATION SUGGESTED.

2. GASTRIC BIOPSY

- GASTRIC MUCOSA WITH CHRONIC GASTRITIS, NO ACTIVITY.

- NO INTESTINAL METAPLASIA OR DYSPLASIA SEEN.

- NO H.PYLORI-LIKE ORGANISMS IDENTIFIED ON GIEMSA STAIN.

So is this enough or do I have to have a positive bllod test or some other test for correlation?


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Lisa Mentor
I had a biopsy done and the nurse practitioner at my gastrointerologist suspects celiac based on my symptoms and the results. She did order the blood test just for correlation. The results of the blood tests are not in yet but this is what the biopsy report says

1. DUODENAL BIOPSY

- DUODENAL MUCOSA WITH FOCALLY INCREASED INTRAEPITHELIAL LYMPHOCYTES AT THE VILLOUS TIP AND UNDERLYING LYMPHOID FOLLICLE.

- THESE CHANGES, ALTHOUGH NON-SPECIFIC, HAVE BEEN ASSOCIATED WITH CELIAC DISEASE. CLINICAL CORRELATION SUGGESTED.

2. GASTRIC BIOPSY

- GASTRIC MUCOSA WITH CHRONIC GASTRITIS, NO ACTIVITY.

- NO INTESTINAL METAPLASIA OR DYSPLASIA SEEN.

- NO H.PYLORI-LIKE ORGANISMS IDENTIFIED ON GIEMSA STAIN.

So is this enough or do I have to have a positive bllod test or some other test for correlation?

There should be a diagnosis/conclusion section of your pathology report. A positive biopsy IS diagnoses enough for Celiac. As also in blood test, biopsies are not always accurate. Both tests can rule Celiac in, but they can't rule it out.

ravenwoodglass Mentor
I had a biopsy done and the nurse practitioner at my gastrointerologist suspects celiac based on my symptoms and the results. She did order the blood test just for correlation. The results of the blood tests are not in yet but this is what the biopsy report says

1. DUODENAL BIOPSY

- DUODENAL MUCOSA WITH FOCALLY INCREASED INTRAEPITHELIAL LYMPHOCYTES AT THE VILLOUS TIP AND UNDERLYING LYMPHOID FOLLICLE.

- THESE CHANGES, ALTHOUGH NON-SPECIFIC, HAVE BEEN ASSOCIATED WITH CELIAC DISEASE. CLINICAL CORRELATION SUGGESTED.

2. GASTRIC BIOPSY

- GASTRIC MUCOSA WITH CHRONIC GASTRITIS, NO ACTIVITY.

- NO INTESTINAL METAPLASIA OR DYSPLASIA SEEN.

- NO H.PYLORI-LIKE ORGANISMS IDENTIFIED ON GIEMSA STAIN.

So is this enough or do I have to have a positive bllod test or some other test for correlation?

What they are saying in the area that I bolded is that the changes they have seen are suggestive of celiac and when they refer to clinical correlation I believe they are saying that it is likely the cause if your symptoms are suggestive of celiac. It does not appear that your doctor did any biopsies of the small intestine villi but concentrated on your duodenum and stomach. Based on this I would certainly give the diet a real good shot for a few months.

The blood test, if you haven't yet gone gluten free could be useful BUT only if it is positive . If you have already had the blood draw and then go ahead and go gluten free. You may have your answer before the blood tests come back.

ANDOBEAR Apprentice
There should be a diagnosis/conclusion section of your pathology report. A positive biopsy IS diagnoses enough for Celiac. As also in blood test, biopsies are not always accurate. Both tests can rule Celiac in, but they can't rule it out.

The diagnoses portion just states GASTRITIS, HIATAL HERNIA

I guess its not in the diagnose section because the report stes clinical correlation is reccommended.

I should also mention this gastroscopy was NOT done to diagnose Celiac. I was being tested for Reflux. We are only exploring the possibility of celiac after the biopsy results. Looking at it now I do have many symptoms and a family history. I thought I had lactose intolerance my whole life and blamed my GI issues on that. After a breath test came up negative for lactose intolerance I definately think Celiac might be the root of my GI issues and several others.

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      Thank you that’s really helpful, hopeful won’t have to have a biopsy.
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