Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Question About Ttg

leadmeastray88

Recommended Posts

leadmeastray88 Contributor
leadmeastray88
Posted

I went to the doctors to get a copy of my celiac 'panel', if thats what you want to call it.

The only thing they tested was my ttG (t Transglutaminase antibody) and it was negative.

How accurate is it? Does this mean for sure that I don't have Celiac's?

Thank you!

-Kim

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


leadmeastray88 Contributor
leadmeastray88
Posted
  • Author

Anyone?

leadmeastray88 Contributor
leadmeastray88
Posted
  • Author

Sorry to 'bump', but if anyone could help out I'd really appreciate it :)

cruelshoes Enthusiast
cruelshoes
Posted
I went to the doctors to get a copy of my celiac 'panel', if thats what you want to call it.

The only thing they tested was my ttG (t Transglutaminase antibody) and it was negative.

How accurate is it? Does this mean for sure that I don't have Celiac's?

Thank you!

-Kim

It is not unheard of to have a negative TtG and still have celiac. The problem is compounded by the fact that they did not run the complete celiac panel. Without the Total IgA score, it i impossible to know whether or not one is IgA deficient. If it were me, I would return to the doctor by phone ir in person, and request the full celiac panel.

Antigliadin IgA and IgG

Anti-tissue Transglutaminase Antibody (tTG) IgA and IgG

Anti-endomysial IgA and IgG

Total serum IgA

It is also possible to have a negative TtG when the damage is still in its early stages.

Open Original Shared Link

Both the anti-tTG and the EMA titers correlate with the severity of villous atrophy [26-29]. As a result in the presence of partial villous atrophy either antibody may be negative. In addition the mode of presentation of the celiac disease, i.e. presence of silent or subclinical celiac disease may be associated with a negative EMA [30]. Clinically seronegative celiac disease is similar to sero-positive celiac disease [23, 28] In view of the possibility of the presence of celiac disease in the absence of a positive anti-tTG or endomysial antibody the presence of a positive IgA AGA should prompt a biopsy [13]. Several studies have demonstrated that reliance on either anti-tTG or endomysial antibody as a single test will underestimate the prevalence of celiac disease [23, 25, 31, 32].
leadmeastray88 Contributor
leadmeastray88
Posted
  • Author

Thank you so much for providing me with that information :) That helped so much.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,966
    • Most Online (within 30 mins)
      7,748
    lorimarielove
    Newest Member
    lorimarielove
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      New Celiac Mama in My 30s

      By Scott Adams · Posted

      Welcome to the forum! This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):    This article may also be helpful:
    • Keith Hatfield
      Does anyone here also have Afib

      By Keith Hatfield · Posted

      Many years ago yes, after eating and going to bed, apparently my esophagus filled with food that my body rejected, the esophagus would lay against the Heart sack (pericardium?) and the heart would respond by becoming arrhythmic. That went away with the strict diet.
    • Ynotaman
      New Celiac Mama in My 30s

      By Ynotaman · Posted

      I was commenting on the report saying it did not mention migraines! Yes it does last paragraph says have not seen any evidence that Celiac cause migraines! I thought this was about truth?
    • trents
      New Celiac Mama in My 30s

      By trents · Posted

      It has been known for some years that celiacs suffer from migraines at a higher rate than the general populatation. It is an established symptom.
    • Ynotaman
      New Celiac Mama in My 30s

      By Ynotaman · Posted

      I suffer so bad with migraines when I eat gluten! Yes diagnosed celiac disease n 2015 and it took me years to discover gluten was behind me having severe migraines.  So yes it happens there has to be others like me!
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.