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18 Month Old Tests Results Are Back


Avasmom12

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Avasmom12 Rookie

HI,

I my daughters (18 month old) test results came back and her Celiac Panel was less than 3. So It is considered negative. Her IGA was 20 the range (24-122) The serum IGA was 18 and the range (24-122). So it is on the lower end. I have been reading this book about children and celiac disease. It states that children with an IGA deficency (sp?) are at an increased risk for celiac disease. I thought that was very interesting. The past couple of days I have feeding my daughter what I have been eating ( I was just diagnosed with celiac disease one month ago). Her stomach is much flatter than normal. (Her symptoms were bloating and allergy to milk) I was just wondering if Anyone else had numbers like that. With Low IGA'S.


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lizard00 Enthusiast

My IgA is very low. My GI told me I would never test positive with the standard order bloodwork. (most docs don't test for IgG unless you specifically ask) He ran the gene test on me, discovered I was double DQ2 which put me in the highest risk bracket. That with the fact that I drastically improved on the diet gave him enough to diagnose me.

Testing in children is generally difficult to get accurate, simply because in many cases they're not old enough to have enough antibodies. And the fact that she's got low IgA is only working against her.

Avasmom12 Rookie

Thanks for the reply back. What is IGG?? I think I might do the gene testing too. I did read that if her IGA level was low she might never test positive.

happygirl Collaborator

If she is IgA deficient, she won't be able to test positive on the IgA based Celiac blood tests.

Here is information about the blood tests:

Open Original Shared Link

lizard00 Enthusiast
Thanks for the reply back. What is IGG?? I think I might do the gene testing too. I did read that if her IGA level was low she might never test positive.

IgG is another antibody that is involved in an immune response, more generalized antibody.

IgA is made by the intestinal immune system... in case you were wondering the difference.

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    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
    • Samanthaeileen1
      Okay that is really good to know. So with that being positive and the other being high it makes sense she diagnosed her even without the endoscopy. So glad we caught it early. She had so many symptoms though that to me it was clear something was wrong.   yeah I think we had better test us and the other kids as well. 
    • GlorietaKaro
      One doctor suggested it, but then seemed irritated when I asked follow-up questions. Oh well—
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