Lab Results ?

[reneelt]

We are new to all of this. My 3 year old son had the lab work done for Celiac and I have a copy of the results but don't totally understand them. The pediatrician has referred us out to Pediatric GI doctor but that is a over a month away still. His labs are as follow, can somebody help me understand them better. I put his results in bold. The doctor says his labs are suspicious but not diagnosed.

Ttg IGA <3 U/mL

<5 Negative

5-8 Equivocal

>8 Positive

Gliadin Antibody IGA 25 (High) u/mL

<11 Negative

11-17 Equivocal

>17 Positive

Gliadin Antibody IGG >100 (High) U/mL

<11 Negative

11-17 Equivocal

>17 Positive

Ttg IGG <3 U/mL

<7 Negative

7-10 Equivocal

>10 Positive

Immunogloblin A Endomysial Antibody SCR 95 Range is 24-121mg/dL

(IGA) W/Refl to Titer Negative

Thank you for your help.

[happygirl]

Your son's doctor ordered five tests -

tTG IgA (negative)

AGA IgA (high)

AGA IgG (high)

tTG IgG (negative)

EMA IgA (negative)

Based on the anti-gliadin IgA and IgG tests, it appears that your son is producing antibodies to gluten.

Also, testing is not as sensitive/specific in young children (meaning, they can often have Celiac but not test positive for it).

Keep him on gluten until all testing is completed.

[reneelt]

Thank you. Since he is producing antibodies does it mean he is most likely at least sensitive to gluten or could some else be causing him to produce them besides Celiac or sensitivity? I really appreciate your response and anybody elses.

[happygirl]

While I'm not a doctor, with both the IgG and IgA tests positive, it would be more likely that he has Celiac or a gluten sensitivity as compared to someone who is negative on both of those tests.

The doctor will probably be interested in doing an endoscopy/biopsy to look for Celiac-related damage in the small intestine.

[nora-n]

If you search the net, they say that in young children, actually teh antigliadin test are better than the newer ttg tests, that is because in young children the imune system is not fully developed yet.

Your son's test are typical for his age and celiac.

The ttg is starting to rise in his tests.

Be sure to give him enough gluten for the endoscopic biopsy to be positive . The next step is the biopsy.

nora

[reneelt]

Thank you so much for the responses.

How much gluten should I be giving him for the tests. I haven't taken any gluten out of his diet but want to make sure I am giving him enough. He loves bread.

[maile]

Thank you so much for the responses.

How much gluten should I be giving him for the tests. I haven't taken any gluten out of his diet but want to make sure I am giving him enough. He loves bread.

for an adult I've seen mentioned here about 3-4 slices of bread per day