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Depression


luceemarie21

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luceemarie21 Newbie

I have been diagnosed with celiac disease for over 2 years and I have been suffering ever since with depression. I am having problems finding an antidepressant that does not contain any wheat or gluten. I am currently taking St Johns Wart but I do not feel that these are having an effect. Please could someone recommend an antidepressant that they have had success with taking.

Hope someone can help


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bmorrow Rookie

I have been taking Zoloft. I won't say that it cures all of the depression, but I take a small dose and I really don't want to increase the amount that I take. I have read on here that Zoloft can casuse Collangeous Colitis, but the doctor says that he doesn't believe this to be true. I have developed Microscopic Colitis, since I have been taking it, but it may not have anything to do with the Zoloft. Good Luck!

darlindeb25 Collaborator

paxil and xanax are gluten free too--i have taken both---its normal to be depressed too--its a lifestyle change we have to make and we mourn food--i read that we celiacs are addicted to gluten and we crave it--dont feel alone--you have to look at the plus side of things--you are alive--going gluten-free you are lowering your chance of stomach cancer, there is still a wide variety of foods you can eat and food definately does not keep us from having a good time--live life one day at a time--dont live for tomorrow, live for today and remember, we celiacs can do anything that anyone else does--we can be just as healthy, with some hard work--keep your chin up----deb

CMWeaver Apprentice

I'm currently taking Zoloft 50mg. My GI doctor suggested I take Zoloft also since the serotonin is not only utilized by the brain but the GI tract as well. I never heard of that before but hey.....I'm not a doctor (although I feel like I'm studying to be one sometimes!)

pmrowley Newbie

WellbutrinXL is gluten-free and has very few side effects.

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    • GlorietaKaro
      Thanks to both of you for your responses!  Sadly, even after several years of very strict gluten avoidance, I remember the symptoms well enough that I am too frightened to risk a gluten challenge— heartbeat and breathing problems are scary— Scott, thank you for the specific information— I will call around in the new year to see if I can find anyone. In the meantime, I will carry on has I have been— it’s working! Thanks also for the validation— sometimes I just feel crushed by disbelief. Not enough to make me eat gluten though—
    • trents
      Welcome to the celiac.com community, @GlorietaKaro! As Scott indicated, without formal testing for celiac disease, which would require you to have been consuming generous amounts of gluten daily for weeks, it would be not be possible to distinguish whether you have celiac disease or NCGS (Non Celiac Gluten Sensitivity). Their symptoms overlap. The difference being that celiac disease is an autoimmune disorder that damages the lining of the small bowel. We actually no more about celiac disease than we do about NCGS, the mechanism of the latter being more difficult to classify. There are specific antibody tests for celiac disease diagnosis and there is also the endoscopy/biopsy of the small bowel lining. Currently, there are no tests to diagnose NCGS. Celiac disease must first ruled out. Researchers are working on developing testing methods to diagnose celiac disease that do not require a "gluten challenge" which is just out of the question for so many because it poses serious, even life-threatening, health risks. But we aren't there yet.
    • lalan45
      That’s really frustrating, I’m sorry you went through that. High fiber can definitely cause sudden stomach issues, especially if your body isn’t used to it yet, but accidental gluten exposure can feel similar. Keeping a simple food/symptom journal and introducing new foods one at a time can really help you spot patterns. You’re already doing the right things with cleaning and separating baking—also watch shared toasters, cutting boards, and labels like “may contain.”
    • Russ H
      I thought this might be of interest regarding anti-EMA testing. Some labs use donated umbilical cord instead of monkey oesophagus. Some labs just provide a +ve/-ve test result but others provide a grade by testing progressively diluted blood sample. https://www.aesku.com/index.php/ifu-download/1367-ema-instruction-manual-en-1/file Fluorescence-labelled anti-tTG2 autoantibodies bind to endomysium (the thin layer around muscle fibres) forming a characteristic honeycomb pattern under the microscope - this is highly specific to coeliac disease. The binding site is extracellular tTG2 bound to fibronectin and collagen. Human or monkey derived endomysium is necessary because tTG2 from other mammals does not provide the right binding epitope. https://www.mdpi.com/1422-0067/26/3/1012
    • Scott Adams
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