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Possibly Celiac


natand

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natand Newbie

Hello,

I am a 31 year old women. I went to see my doctor due to a vast array of symptoms, including fatigue, brain fog, obesity with Inability to lose weight, Diarrhea, upset stomach, odd sensations in my hands and feet, severe migraine's with stroke symptoms, feeling worse when I exercise, bad memory, depression, anxiety, the list goes on. Really I have a complete feeling of being unwell. My doctor ran a huge set of blood and urine tests on me. The labs show that I have a severe Vitamin D deficiency, a 14, My doctor said that should be at least 50. Also, My liver results came back high. My doctor has scheduled me for a liver ultrasound. All thyroid tests came back as normal. My tissue transglutaminase came back at 12. From what I have found searching around the internet, it seems that anything over a 9 is a high positive for celiac disease. I am still waiting to hear back from my doctor. I am hoping for some insight on what all of this means. Any information or advise will be very appreciated.


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Ahorsesoul Enthusiast

Can you list all your lab results?

natand Newbie
Can you list all your lab results?

Here they are. I don't know what most of them mean. Maybe you do. Thank You.

Tissue Transglutaminase Ab, IgA

Tissue Transglutaminase Ab, IgA. 12

11/12/2009

Ferritin

(ng/mL) 86

11/12/2009

TrIIodothyronine, Total

T3 121

(ng/dL)

11/12/2009

Free T4 (Free Thyroxine)

T4, Free 1.36

Comprehensive Metabolic Panel

11/06/2009

K 4.2

ALT 63

Na 135

Ca 9.1

AST 52

Cl 105

Creatinine 0.76

CO2 24

Prot 7.1

Anion Gap (Na Cl CO2) 6

GFR Est. by MDRD eq. >60

Alb 3.8

Bili, Total 0.5

BUN 12

Alk Phos 73

Glucose 78

11/12/2009

Urine Macro

11/06/2009

Color Normal

Appear Normal

Nitrite Negative

Hgb, Ur Negative

Glucose, Ur Negative

Collect Method, Ur Urine

Leuk Esterase Negative

Ketones, Ur Negative

Sp Gr, Ur 1.012

Prot, Ur Negative

Urine Microscopics

11/06/2009

Bact Negative

RBC, Ur 3

WBC, Ur 2

Mucus 1

Epi, Ur 2

Manual Differential

11/06/2009

Diff Type Manual Diff

RBC Morph NORMOCYTIC & NORMOCHROMIC NCNC

Lymphs, Abs 2.2

Plt Est Agrees with count PLTOK

Mono, Manual 8

Lymph % 29

Neut, Manual 63

Neut, Abs 4.9

Mono, Abs 0.6

Vitamin D 25 Hydroxy

25 Hydroxyvitamin D2 And D3 14

11/06/2009

Thyroid Stimulating Hormone

TSH 1.89

(uIU/mL)

11/06/2009

pH 5.5

CBC Without Diff

11/06/2009

RBC 4.60

HGB 14.8

MPV 9.8

MCHC 34.6

MCH 32.1

Nucleated RBCs,

MCV 92.8

PLTS 220

Hct 42.7

WBC 7.7

RDW 13.1

Vitamin B-12 (RIA)

B12 1035

(pg/mL)

11/06/2009

tunibell Rookie

There should be a scale associated with your TTG numbers. Different labs use different ranges, so the numbers in and of themselves are impossible to evaluate without the range.

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    • trents
      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      This article, and the comments below it, may be helpful:    
    • Scott Adams
      That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people with celiac or DH don’t react every time they’re exposed, so lack of symptoms doesn’t rule it out. Given your history and family cancer risk, this is something I’d strongly discuss with a celiac-experienced gastroenterologist or dermatologist before attempting a challenge on your own, so risks and benefits are clearly weighed.
    • Greymo
      https://celiac.org/glutenexposuremarkers/    yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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