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Deficient Iga Affect Igg Results?


JamTart

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I was recently tested for celiac after a positive home biocard test. Results came back apparently negative. Had both deamidated antibody for IgA and IgG as well as ttg igA I think. All came back negative. I understand IgA deficiency could possibly have caused false negs with regards to the IgA value, but could it have affected the IgG value? Do I need to ask for any further tests (EMA? Etc) to accompany the total IgA to rule out IgA deficiency as a possible cause for neg results? I have every symptom in the book! Frustrating. Anyone been seronegative with a positive biopsy? I'm thinking of pushing for a biopsy. (I also posted under 'Push for more testing?' with a few more details)

Thankyou so much for any/all responses!! :) Also I wouldn't say I generally eat a diet heavy in gluten- 1-2 pieces of bread a day, sometimes pasta and I don't watch for it in Cannes goods etc- lots of fruit, meat, veggies. Should I try to eat more gluten than that until this is figured out?


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JamTart Rookie

Thanks for Replying Diana- I couldn't see the content of your reply though?! I'm new to all this :)

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  • Posts

    • Fayeb23
      Thank you that’s really helpful, hopeful won’t have to have a biopsy.
    • RMJ
      That means the normal range (i.e. not celiac disease) would be a result less than 14.99.  Your result is WAY above that. Some gastroenterologists would diagnose that as celiac disease even without a confirming biopsy because it is more than ten times the top of the normal range.
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      Thank you. These were the results TTG ABS NUMERICAL: > 250.0 U/mL [< 14.99]  Really don’t understand the results!
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      Clearly from what you've said the info on Dailymed is much more up to date than the other site, which hasn't been updated since 2017. The fact that some companies might be repackaging drugs does not mean the info on the ingredients is not correct.
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