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Recent Activity
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- trents replied to dominiqueccms's topic in Coping with Celiac Disease1Old to diagnosis
Welcome to the forum, @dominiqueccms! Unfortunately, your story is all too common. Some older physicians are dismissive when it comes to gluten intolerance disorders and have this attitude like, "It's the latest fad disease." My advice to you is to get another doctor who has more current knowledge in this area and will take this seriously. In the meantime... -
- trents replied to Cat M's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3
Weakly positive DGP IgA
By the way, you need to repost those numbers in your first post and add the reference ranges. Different labs use different reference ranges so the test scores by themselves aren't very helpful, especially when the values may be borderline positive. It would need to be in a new post window as the edit function times out quickly such that you can't go back... -
- Cat M replied to Cat M's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3Weakly positive DGP IgA
I ate two pieces of toast each morning for three weeks prior to testing. The rest of the day I ate whatever. I am going to increase the gluten for four weeks and ask my doc to retest. I did read that false positives are possible, so I think it’s reasonable to retest. But I am very new to this, so not feeling confident. -
- trents replied to Cat M's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3
Weakly positive DGP IgA
Welcome to celiac.com, @Cat M! Were you consuming generous amounts of gluten for a significant period of time (weeks/months) before the blood draw and test results you posted? I ask because you say you would like to be retested after consuming gluten for a few weeks. Current guidelines for the gluten challenge call for the daily consumption of at least... -
- Wamedh Taj-Aldeen posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms0Positive TTG antibody and negative EMA antibody
I recently reviewed a patient with a positive tissue transglutaminase (tTG) antibody but negative endomysial antibodies (EMA). The patient is asymptomatic, and duodenal biopsies—taken while on a normal gluten-containing diet—were reported as normal. Given the discordant serology and absence of histological changes, I understand that the probability of ...
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Welcome to the forum, @dominiqueccms! Unfortunately, your story is all too common. Some older physicians are dismissive when it comes to gluten intolerance disorders and have this attitude like, "It's the latest fad disease." My advice to you is to get another doctor who has more current knowledge in this area and will take this seriously. In the meantime, this might be helpful: In six months to a year you would do well to get your antibody numbers rechecked to see if you are succeeding in your efforts to eat gluten free. Do you have the numbers from the original testing? -
By the way, you need to repost those numbers in your first post and add the reference ranges. Different labs use different reference ranges so the test scores by themselves aren't very helpful, especially when the values may be borderline positive. It would need to be in a new post window as the edit function times out quickly such that you can't go back and make changes to the original. What symptoms do you have? What has led you to investigate the possibility of having celiac disease?
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I ate two pieces of toast each morning for three weeks prior to testing. The rest of the day I ate whatever. I am going to increase the gluten for four weeks and ask my doc to retest. I did read that false positives are possible, so I think it’s reasonable to retest. But I am very new to this, so not feeling confident.
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Welcome to celiac.com, @Cat M! Were you consuming generous amounts of gluten for a significant period of time (weeks/months) before the blood draw and test results you posted? I ask because you say you would like to be retested after consuming gluten for a few weeks. Current guidelines for the gluten challenge call for the daily consumption of at least 10g of gluten (the amount found in about 4-6 slices of wheat bread) for at least 2 weeks. But I would go for longer than that to be sure, say 4 weeks. Testing is invalid when people have been gluten free or even skimping on it.
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By Wamedh Taj-Aldeen · Posted
I recently reviewed a patient with a positive tissue transglutaminase (tTG) antibody but negative endomysial antibodies (EMA). The patient is asymptomatic, and duodenal biopsies—taken while on a normal gluten-containing diet—were reported as normal. Given the discordant serology and absence of histological changes, I understand that the probability of coeliac disease is low. However, I would appreciate your guidance on the following: Is routine follow-up required in such a case? What is the risk of progression to overt coeliac disease in the future? Would HLA DQ2/DQ8 typing be useful here to help guide long-term management or exclude the diagnosis confidently? I would be grateful for your thoughts.
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