Is Deaminated Gliadin Iga Of 45 (0-19) A Yes Or No?

[ksue12]

I had that test result two years ago, and at the same time was told I did NOT have celiac because the other tests that more specifically represent celiac were negative, along with my biopsy results. Any thoughts?

[mushroom]

Welcome, ksue.

The DGP (deamidated gliadin protein) is the newest test for gluten sensitivity and is considered to be the most specific for celiac disease. You do not have to test positive on all the tests - that is why they run the entire panel. Your DGP was a definite positive.

Your negative biopsy could be due to your doctor not taking enough samples, taking them from the wrong place, or the pathologist not being experienced in reading celiac slides. Do you still have (or can you get) a copy of the pathologist's report and tell us what it said? Sometimes doctors are not very experienced in reading these and don't know what signs to look for. You could have been in the early stages of damage.

[GFinDC]

Yep, one positive blood test is all it takes.

[ksue12]

Thanks for both of your replies!

Mushroom, so does this mean I most likely have celiac or gluten intolerance? And, I could not find the results of the biopsy. I think it was in my online chart, but for some reason I can't find it anymore. All I saw on the paper that they handed me when I finished the endoscopy was that some samples were taken from the "postbulbar duodenum", but that the duodenum looked normal during the scope.

[nvsmom]

Welcome ksue.

Whoever told you you were not a celiac was mistaken. Unlike celiac disease, there is no test that will indicate non-celiac gluten intolerance (NCGI). This food sensitivity is diagnosed by how well you respond to a gluten-free diet. NCGI sufferers will have the same symptoms as celiacs but they will not have the intestinal damage. Your positive test indicates celiac (as far as I can remember).

The duodenum is the upper part of the small intestine where celiac damage usually occurs so they were looking in the correct spot. This damage may or may not be visable during the scope; the biopsy samples often need to be checked under magnification to see the damage. That damage is often spotty so if a small nummber of samples was taken, it could have been missed... sounds like it was.

Good luck with the diet change. There are many helpful people around here to give good advice, look around and ask questions. Best wishes.

[GottaSki]

Welcome!

I'd add that it is time for another full celiac panel. If you haven't removed gluten at all, you may now have more positive tests.

Good luck to you