Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Igg/iga/ttg


Mom22

Recommended Posts

Mom22 Apprentice

Both our daughter and son have been diagnosed with celiac disease this year via biopsies. Both were asymptomatic, but our son was experiencing constipation which warranted further testing. It was only through a diligent pediatrician did he order several blood screens and one was the gluten enterpathy and that started the ball rolling. He had a biopsy, came back positive, then his sister, had blood work, was elevated, had a biopsy which was inconclusive and had a second opinion by Dr. Fasano of her biopsy slides, which was positive for celiac. I had bloodwork done and all screens were negative. My husband had bloodwork done and also the HLA test and he does have the DQ2 & DQ8 genes. His IGG (112) and IGA (27) are elevated, but the TTG (4) is within normal limits. My husband is seeing Dr. Fasano in September. Due to knowing that the celiac came through my husband's side of the family, we advised his parents to have the initial blood screen done. My mother in law has had her test and the nurse practioner of her family physician called and said she was negative. She didn't have any of the #'s of the results. I asked her if she could get a copy and mail it to me only because initially, my husband's dr. said he was negative, but then when we received a copy of the results, we pursued further testing. I am a work in progress as far as my knowledge of celiac goes, but her results, I think may warrant further testing or seeing a specialist. Please tell me if I am wrong as I don't want to alarm my mother in law. I realize my mother in law could be a carrier and the celiac has not and may never develop in her. My father in law hasn't had his blood work done yet. What do you think?

My mother in law's results.

IGG: 27.7

IGA 42.1

TTG 6

Thanks for an light you can shed on this.

Mom 2 2 celiac children


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



mat4mel Apprentice

I am totally confused.. all of those results sound positive for celiac to me.. why would they say they were negative?

Mom22 Apprentice

Thanks. You just confirmed what I have been thinking all along. I thought the same thing, but they are telling my mother-in-law that her results are negative. I am thinking otherwise. Thank you for your input.

lovegrov Collaborator

Also sounds positive to me.

richard

gf4life Enthusiast

Here is my interpretation. See, my doctors office considers (wrongly) anything under 30 to be negative on the IgA and IgG, and under 20 negative on the tTg. So my interpretation is that they are ignoring the obviously positive IgA, since they seem to think the other two are negative.

The problem with this is that the blood tests are NOT as accurate as the doctors think and with even one of them showing positive then it is most likely celiac. Either further testing or a trial gluten-free diet is in order, but I don't recommend the diet until after the biopsy, assuming a biopsy might happen in the future. I personally chose Enterolab after the doctors insisted for two years that my tests were all negative, and the biopsy performed after being gluten-free was negative. Enterolab showed that I not only had the genes, but was producing positive level antibodies to gluten and casein in my intestines, but I did not have severe damage to my intestines (probably since they healed partially while I was gluten-free!).

I hope your mother-in-law doesn't have to be sick for long. Please urge her to get more testing done (or try the diet).

God bless,

Mariann

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,606
    • Most Online (within 30 mins)
      7,748

    TGreen
    Newest Member
    TGreen
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Scott Adams
      It seems like you have two choices--do a proper gluten challenge and get re-tested, or just go gluten-free because you already know that it is gluten that is causing your symptoms. In order to screen someone for celiac disease they need to be eating gluten daily, a lot of it--they usually recommend at least 2 slices of wheat bread daily for 6-8 weeks before a blood screening, and at least 2 weeks before an endoscopy (a colonoscopy is no used to diagnose celiac disease). Normally the blood panel is your first step, and if you have ANY positive results there for celiac disease the next step would be to take biopsies of your villi via an endoscopy given by a gastroenterologist.  More info on the blood tests and the gluten challenge beforehand is below: The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate. Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:   Not to discourage you from a formal diagnosis, but once you are diagnosed it may lead to higher life and medical insurance rates (things will be changing quickly in the USA with the ACA starting in 2026), as well as the need to disclose it on job applications. While I do think it's best to know for sure--especially because all of your first degree relatives should also get screened for it--I also want to disclose some negative possibilities around a formal diagnosis that you may want to also consider.  
    • Wheatwacked
      Yes.  Now, if you hit your finger with a hammer once, wouldn't you do your best not to do it again?  You have identified a direct connection between gluten and pain.  Gluten is your hammer.  Now you have to decide if you need a medical diagnosis.  Some countries have aid benefits tgat you can get if you have the diagnosis, but you must continue eating a gluten-normal diet while pursuing the diagnosis. Otherwise the only reason to continue eating gluten is social. There are over 200 symptoms that could be a result of celiac disease.. Celiac Disease and Non Celiac Gluten Sensitivity  both cause multiple vitamin and mineral deficiency.  Dealing with that should help your recovery, even while eating gluten.  Phosphatidyl Choline supplements can help your gut if digesting fats is a problem,  Consider that any medications you take could be causing some of the symptoms, aside from gluten.        
    • trents
      Welcome to the forum, @Ben98! If you have been consciously or unconsciously avoiding gluten because of the discomfort it produces then it is likely that your blood antibody testing for celiac disease has been rendered invalid. Valid testing requires regular consumption of generous amounts of gluten. The other strong possibility is that you have NCGS (Non Celiac Gluten Sensitivity) which shares many of the same symptoms with celiac disease but does not have the autoimmune component and thus does not damage the small bowel lining. It is 10x mor common than celiac disease. There is currently no test for NCGS. Celiac disease must first be ruled out. Some experts in the field believe it can be a precursor to the development of celiac disease. Having one or both of the primary genes for developing celiac disease does not imply that you will develop active celiac disease. It simply establishes the potential for it. About 40% of the population has the genetic potential but only about 1% develop active celiac disease. 
    • Ben98
      TTG blood test and total IGA tested on many occasions which have always remained normal, upper GI pain under my ribs since 2022. I had an endoscopy in 2023 which showed moderate gastritis. no biopsy’s were taken unfortunately. genetic test was positive for HLADQ2. extreme bloating after eating gluten, it’ll feel like I’ve got bricks in my stomach so uncomfortably full. the pain is like a dull ache under the upper left almost like a stitch feeling after a long walk. I am just wanting some advice has anyone here experienced gastritis with a gluten issue before? thank you  
    • Wheatwacked
      "Conclusions: The urinary iodine level was significantly lower in women with postmenopausal osteoporosis, and iodine replacement may be important in preventing osteoporosis"  Body iodine status in women with postmenopausal osteoporosis Low iodine can cause thyroid problems, but Iodine deficiency will not show up in thyroid tests.  Iodine is important for healing, its job is to kill off defective and aging cells (Apoptosis). Skin, brain fog, nails, muscle tone all inproved when I started taking 600 mcg (RDA 150 - 1000 mcg) of Liquid Iodine drops. Some with dermatitis herpetiformis, Iodine exacerbates the rash.  I started at 1 drop (50 mcg) and worked up to 12 drops, but I don't have dermatitis herpetiformis.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.