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What Constitutes An Iga "deficiency"?


DChelleD

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DChelleD Rookie

My bloodwork showed my total IgA at 67 range is 81-463

Allergist said my IgA was low but clinically insignificant. I did not get to talk to him directly and don't plan on any further visits with him.

I just want to know what constitutes an IgA "deficiency"? My number is low but does it have to be low to a certain point to be considered a deficiency rather than just low? Or, is anything below range considered a deficiency?

Will a gluten-free or gluten-light diet affect the total IgA bloodwork?


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nora-n Rookie

There have been several postings about that here before, and even a low-normal total IgA can skew the IgA based celiac tests they said here.

 

I do not know about the last question.

nvsmom Community Regular

You have an IgA deficiency. You do not have a normal amount of IgA, and they (usually) base lab's normal ranges on what 95% of the population has, so you are in the minority. Below the range is usually considered deficient, although there are varying degrees of that.

 

Your diet will not affect your total serum IgA, but a gluten lite or gluten-free diet COULD POTENTIALLY affect any celiac tests that use IgA (like DGP IgA , tTG IgA, EMA IgA, AGA IgA). The longer you are gluten-free, the more likely it becomes that your diet will affect your celiac test results.

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    • RMJ
      I agree with @trents, they should have run a total IgA.  What was the normal range for the DGP IgA test?  Different labs use different units thus have different normal ranges.
    • Churro
      Thanks for your assistance. 
    • trents
      Get your total IGA checked to make sure your celiac antibody test scores are trustworthy.   
    • Churro
      I do eat 4 slices of wheat bread with almond butter. Yes it was a reference to my iron consumption. 
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      To give you a frame of reference for pretesting gluten consumption necessary to ensure valid antibody testing, here is the current recommendation for those who have been on a gluten free diet: The daily consumption of at least 10g of gluten (about the amount in 4-6 slices of wheat bread) for at least two weeks. Not sure why you mentioned eggs and chicken. They are not sources of gluten. Was that in reference to dietary iron consumption?
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