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Exact Details Of Endocscopic Biopsy

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Posted 28 April 2004 - 10:21 AM

Hi all, I hope you can help me in a hurry. It's been so long since I went through my biopsy that I cannot recall the appropriate methodology for the endoscopy. My mom is having an endoscopy for another reason but had bloodwork done last week that indicated that it might be prudent to check for celiac disease/villi damage. Anyhow I am fairly confident that her GI is not too knowledgable in this area and she won't switch her procedure at this point to someone in the area who is more knowledgable with celiac disease, but she is willing to have her GI pull the biopsy for celiac disease. So now I need to give her very specific information as to what to give to him re: what needs to be done for a proper biopsy. Even if he knows what to do, if nothing else, it will help to educate her. For some reason despite my surfing and net abilities I can't seem to pull this information off the net. Can anyone help me out here? She needs to call him ASAP and so any input would be appreicated.

It's great to finally join y'all. I'm a newbie here.

Thanks so much!
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Posted 28 April 2004 - 11:57 AM

I don't think I have all the details you need but I DO know that he needs to take something 8-10 samples from various areas of the small bowel. Damage can be spotty and if you take just 2 or 3 samples you can miss it. If he doesn't know what he's looking for he needs to let somebody with more expertise read the slides.

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Posted 28 April 2004 - 06:55 PM

One thing they need to do when they take the biopsies (and most doctors don't do this) is to look at the tissue samples on the cellular level. I think it is called a celiac disease-3 stain. They can then count the number of lymphocytes (anything over 20 is conscidered celiac disease). This would only need to be done in the absence of visible damage to the villi, but it needs to be specially requested by the doctor or the lab won't do it.

I found this out too late, and since I had no visible damage I do not have the diagnosis. I will NOT do another gluten challenge (the first one was horrible) and so I will have to wait until they accept Enterolab in the mainstream medical field.

God bless,
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~West Coast-Central California~

Mariann, gluten intolerant and mother of 3 gluten intolerant children

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