No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter




Ads by Google:



Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts

SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

What is the difference between celiac disease and gluten intolerance?*

The following was posted by Kemp Randolph on the Celiac Listserv news group krand@pipeline.com:

The difference is that between two immune related reactions, allergy and intolerance. I asked the question of the technical difference between the two some time ago and got no response. Its not based on overt symptoms, thats for sure. Were also not talking about the difference between latent celiac disease and overt weight-loss, apple belly CD. You can be allergic and intolerant of the same substance or food In the case of milk, its lactose(milk carbohydrate) intolerance and milk protein allergy.

My non-professional stab at the difference between intolerance and allergy then. Both can lead to intestinal damage. Theres a table in Marshs book showing that --page 155 , figure 6.13. Type 3 damage (flat destructive ) can occur from milk, soy, egg.... as well as celiac disease.

Ads by Google:

The reaction to an intolerance seems to be that the substance is not digested. The immune part of the response involves only the circulating immunoglobins IgA, maybe IgG and related immune cells, receptors.

The immune reaction to an allergy involves IgE. The substance may still be digested, but there may be allergic responses elsewhere outside the gut.

Apple belly celiac disease is an intolerance. The problems elsewhere in the body, except for cancer, are related to nutritional deficiencies. The link to other autoimmune diseases is statistical genetics when two (or more) genes for each of two conditions are close together.

For more information see the Allergy vs. Intolerance page.

Celiac.com welcomes your comments below (registration is NOT required).





Spread The Word







Related Articles



7 Responses:

 
Freddie
Rating: ratingfullratingemptyratingemptyratingemptyratingempty Unrated
said this on
16 Nov 2008 6:46:08 PM PDT
I still don't know the difference between them--they say they are different but how are they?

 
Marie Doherty
Rating: ratingfullratingfullratingemptyratingemptyratingempty Unrated
said this on
15 Aug 2009 5:17:56 PM PDT
I do not understand either what the difference is between them!! Can someone clarify please

 
L. Rensch
Rating: ratingfullratingemptyratingemptyratingemptyratingempty Unrated
said this on
31 Aug 2010 1:13:50 PM PDT
You need to do some more research. Celiacs, allergies and intolerance do not all damage the gut. Celiacs is the only one that damages the gut and does not allow nutritional absorption. Food allergies cause allergy type symptoms-skin rashes, itchy skin, and/or tummy problems. Intolerance bother the tummy, cause no damage, and go away once food has passed through.

 
Laura Bachner
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
25 Oct 2011 11:34:37 AM PDT
Um I hate to differ with you L. Rensch. I have gluten intolerance not celiac and I can officially tell you that as of now when I ingest gluten it takes 3 days for my tummy to be able to handle food well enough to feel normal again.

 
Karen
Rating: ratingfullratingemptyratingemptyratingemptyratingempty Unrated
said this on
28 Apr 2012 5:28:48 PM PDT
Isn't 3 days how long it typically takes your body to digest and expel food? Unless you have a particularly fast metabolism, it really is about getting the gluten out of your system whether your have an intolerance OR an allergy.

 
Paula
Rating: ratingfullratingemptyratingemptyratingemptyratingempty Unrated
said this on
20 Dec 2011 12:40:43 AM PDT
I just found out I'm. Allergic too!! It also takes about 3 days for my tummy to stop hurting!!

 
Rose

said this on
02 Dec 2014 10:52:16 AM PDT
I have heard diverticulitis is the after effect of years of gluten intolerance.....




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:

All Activity
Celiac.com Celiac Disease & Gluten-Free Diet Forum - All Activity

JaneWhoLovesRain, what is odder to me than that there is an older disease that Doctor's have forgotten that explains many of the same symptom's and doctor's do not even think about it today since the "War on Pellagra" was declared over a 100 years and why doctor's don't (at least in the West) think about it any more. Dr. Heaney wrote a nice online article about this topic. http://blogs.creighton.edu/heaney/2013/11/18/pellagra-and-the-four-ds/ Here is fairly recent article about how Pellagra can present in patients and the title says' it all from the International Journal of Dermatology. https://www.researchgate.net/publication/227807440_Pellagra_Dermatitis_dementia_and_diarrhea Dermatitis, dementia and Diarrhea are the 3 D's (4th D is death) of Pellagra. Typically it is only diagnosed today if you are in a subset of the population like an alcoholic for example or you have a gastric bypass. See this article from the New England Journal of Medicine http://www.nejm.org/doi/full/10.1056/NEJMicm050641 and despite all the signs of Pellagra (skin issues etc.) . . .. Pellagra in it native tongue (Italian) where it was first diagnosed was called "rough/sour skin" who knows that today??????? Very few I would venture to guess. The NEJM can only say they have "Pellagra-like dermatitis" it has been so long since any doctor's seen it they can't (with confidence) diagnose it clinically. But taking Niacinamide 3/day for 6 months can help alleviate your symptom's if indeed the DH of Celiac is the dermatitis of Pellagra being medically misdiagnosed. Here is a an article featured on celiac.com about why/how Pellagra can be confused for Celiac disease. https://www.celiac.com/articles/24658/1/A-Differential-Diagnosis-How-Pellagra-Can-be-Confused-with-Celiac-Disease/Page1.html Because they haven't seen Pellagra in 75+ years no one recognizes it anymore. ****this is not medical advice. I hope this is helpful. Knitty Kitty and I are the Niacin warriors on this board. See this thread where Knitty Kitty says Niacin helped the itching of DH. If that is so then it might help your DH (if you have it) and your GI problems too if they are caused by co-morbid Pellagra. see my blog post about where I say "I had Celiac Disease and Developed Pellagra" that talks about this in more detail. Again good luck and your continued journey and I hope this is helpful. 2 Timothy 2: 7 ?Consider what I say; and the Lord give thee understanding in all things? this included. posterboy by the grace of God,

I should say I am confused about how to interpret--- Does this mean celiac or no celiac? Thank you all---I greatly appreciate it.

KathleenH, I swear by MatteosPizza and they make National Delivery. I have been known to buy them by the dozen. https://www.matteospizza.com/ BellaMonica's is not a bad corn based crust. By not bad I mean "suprisingly good" that can be bought at most grocery stores. Here is there ZIP locator page to see if they are carried in your local area. http://glutenfreepizza.typepad.com/gluten-free-pizza/where-to-find-bella-monica.html I hope this is helpful. posterboy,

Hey all--have Hashimoto's and am being worked up for epigastric discomfort and IBS like symptoms--- My blood work had an IgA within the lower end of normal range, negative TTG, but weakly positive DGP. My endoscopy showed a "nodular" duodenum with the biopsy stating there was "reactive lymphoid hyperplasia"... I have a follow-up with the GI in 3 weeks. Wondering about any help?

DH wasn't linked to celiacs until 1967 from my research...