My Negative Blood Test Results.

[taynichaf]

First of all, since the beggining of the year I have been eating light gluten, if any, do to "clean eating". These tests were done after only 6 days of eating A LOT of gluten.. and the week before I had a few glutenous days.

 

Immunoglobulin A (IgA), S           (results) 217    (unit) mg/dL   (ref. value) 60 - 337

Under these results is says:

 Negative serology. Celiac disease unlikely. However, approximately 10% of patients who are already adhering to a gluten-free diet may be seronegative. If celiac disease is highly clinically suspected, consider HLA-DQ typing.

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Tissue Transglutaminase Ab,   IgA,   S      <1.2            U/mL                      <4.0 (negative)

 

 

My other tests were

 

WBC COUNT - 10.9 (High)

MVP - 8.6 (Low)

 

FERRITIN SERUM - 19 (Low)

 

 

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If i am not celiac, i'm gluten intolerant.. But I just want to know for sure if i'm celiac. I like to know WHY I cant eat gluten. What should my next step be?? DNA test just too see if it can be ruled out?

 

 

 

 

 

 

[mushroom]

The first test, the Immunoglobulin A (IgA), S, is the control test to make sure that you manufacture what is considered a normal amount of antibodies, and you do.

 

The second test is the doctors' preferred test, because it measures the antibodies that are damaging tissue in the small intestine (tissue Transglutaminase).  There usually needs to be quite a bit of damage for this test to be positive.

 

There is a newer, more sensitive test with great specificity for celiac, called the DGP (deamidated gliadin peptide) which can pick up celiac disease earlier then the tTG.  Not too many doctors have a lot of experience with this test.  If I were you I would ask to have this test run.  I hope you are still eating gluten? 

[taynichaf]

The first test, the Immunoglobulin A (IgA), S, is the control test to make sure that you manufacture what is considered a normal amount of antibodies, and you do.

 

The second test is the doctors' preferred test, because it measures the antibodies that are damaging tissue in the small intestine (tissue Transglutaminase).  There usually needs to be quite a bit of damage for this test to be positive.

 

There is a newer, more sensitive test with great specificity for celiac, called the DGP (deamidated gliadin peptide) which can pick up celiac disease earlier then the tTG.  Not too many doctors have a lot of experience with this test.  If I were you I would ask to have this test run.  I hope you are still eating gluten? 

Okay, I made a new doctors appointment at a different place(last doctor couldnt test for full panel or anything). I'll talk to my new doctor and go from there, and I might just request a DNA test to start out with. If that test is positive I'll restart a gluten challange and go from there... I will make sure that I get the DGP test this time!

 

I havent been eating gluten.... But it hasnt even been 2 weeks since going gluten free, so I will start glutening myself for about 6 weeks before a new blood test.... Does this sound good??

[mushroom]

Sounds like a good plan.  If you are starting fresh with a new doctor, get the whole panel redone:

 

Anti-Gliadin (AGA) IgA
Anti-Gliadin (AGA) IgG
Anti-Endomysial (EMA) IgA
Anti-Tissue Transglutaminase (tTG) IgA
Deamidated Gliadin Peptide (DGP) IgA and IgG
Total Serum IgA