Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Son's Prometheus Test Results

bayba792

Recommended Posts

bayba792 Rookie
bayba792
Posted

I have posted on here several times and you all have been so kind and patient with me. I just received my son's Prometheus test results and would like some clarification.

 

This is my son's test results:

 

DGP IgG 0.4 EU/ml - <4.9 EU/ml

DGP IgA 1.7 EU/ml - <6.1 EU/ml

TTG IgA 0.6 U/ml - <10.3 U/ml

EMA IgA NEGATIVE - NEGATIVE

TOTAL IgA 209 mg/dl   41-395 mg/dl

 

CELIAC RISK HAPLOTYPE DETECTED:

 

DQ2.2 (HLA DQA1*0201:DQB1*0202) AND DQ8 (HLA DQA1*03:DQB1*0302)

 

CATEGORY #       DQ GENOTYPE     INCREASED RISK    RELATIVE RISK

        6                      DQ2/DQ8                    14X                      VERY HIGH

 

My son has been gluten-free for 5 months before this test was done so the Dr said that she would expect the serological markers to be negative.

 

This was my husband's results to the same test:

 

Deamidated Gliadin Peptide Antibody,
IgG (DGP IgG) 9.2 EU/ml + <4.9 EU/ml
Deamidated Gliadin Peptide Antibody,
IgA (DGP IgA) 15.0 EU/ml + <6.1 EU/ml
Anti-Human Tissue
Transglutaminase IgA (TTG IgA) 2.3 U/ml - <10.3 U/ml
Anti-Endomysial IgA IFA (EMA IgA) Negative Negative
Total Serum IgA
By Nephelometry (TOTAL IgA) 308 mg/dl <3 Yrs: 8-220 mg/dl
3-13 Yrs: 41-395 mg/dl
>13 Yrs to adult: 44-441 mg/dl
Celiac Risk Haplotype: DQ8(HLADQA1*03:DQB1*0302)AND OTHER NON-RISK
ALLELES.
Category # DQ Genotype Increased Risk Over General Population Relative Risk
------------------------------------------------------------------------------
3 DQ8 HETEROZYGOUS 2X MODERATE
------------------------------------------------------------------------------
 
sorry so long but from what I understand is that I carry DQ2 and that is why my son has both? Do I need to be tested and also my 5 year old son? We have no GI problems when we eat gluten but we are completely gluten-free in the house and I do not cheat because I have noticed improvements other than GI clear up on gluten-free diet but I notice that if my youngest son eats gluten at school (cupcakes when it's someone's birthday) he gets a rash on his butt cheeks and under his testicles, could this be related?
 
Thank you!!!!
<3 <3 <3
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Lock Newbie
Lock
Posted

Whether you get yourself and your son tested is up to whether you want to spend the money and go through the trouble but yes, the gluten sensitive/celiac genes are in your family and it is probably good for all of you that you are gluten free. For your 5 year old, from my perspective with my children now in their twenties, I no longer have any control over their health. Looking back, if they had had the gene tests back when they were little I would have got them so that they would maybe take being gluten free more seriously.

 

From my interpretation of the test results, which I am an amateur by the way, it does seem you have the DQ2 gene and your husband has the DQ8 but heterogenous which means he also has a non-gluten gene. IF you also have one gluten gene and one non gluten gene then your 5 year old has a 1/4 chance of having NO gluten genes, if that makes sense. But that also means he has a 75% chance of having at least one. So if you don't get him gene tested, it would be good to watch him for symptoms. Also, living in a gluten free home could potentially protect him from getting sick later. However, you will rapidly lose control as he grows, goes to school, etc.

 

I don't think it would be worth it to go on gluten to try to tease out a diagnosis, but in my opinion, getting the test and having the information to give your child is a good idea. Then as he becomes an adult and has to make his own food choices he will at least know if he is at risk of celiac disease or gluten related problems.

w8in4dave Community Regular
w8in4dave
Posted

I agree with Lock. I think having them tested does make for better choices in the future. 

nvsmom Community Regular
nvsmom
Posted

Yes, you and your 5 year old should be tested, your son especially and his test should be repeated every few years if it is negative.

I hope your husband is going gluten-free after those positive tests.

bayba792 Rookie
bayba792
Posted
  • Author

Thank you so much for responding. I will get my 5 year old son tested, I was under the impression that he would have both like my oldest so it would be good to find out. I called my son's doctor and made an appointment for the testing.

 

nvsmom, my husband was gluten free for 3 months before this test so the GI specialist is keeping a close eye on him because of his numbers. He wants to see my husband in 3 months to see if his numbers come down more. He is feeling excellent now that he is gluten free. 

nvsmom Community Regular
nvsmom
Posted

Glad he is feeling good. It takes a while for those numbers to come down, doesn't it?

Good luck with all the testing. :)

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Colleen H
      - Colleen H replied to Colleen H's topic in Coping with Celiac Disease
      2

      Gluten related ??

      Thank you so much for your response Yes it seems as though things get very painful as time goes on. I'm not eating gluten as far as I know. However, I'm not sure of cross contamination. My system seems to weaken to hidden spices and other possibilities. ??? if cross contamination is possible...I am in a super sensitive mode of celiac disease...
    2. Jmartes71
      - Jmartes71 replied to Jmartes71's topic in Coping with Celiac Disease
      4

      My only proof

      EXACTLY! I was asked yesterday on my LAST video call with Standford and I stated exactly yes absolutely this is why I need the name! One, get proper care, two, not get worse.Im falling apart, stressed out, in pain and just opened email from Stanford stating I was rude ect.I want that video reviewed by higher ups and see if that women still has a job or not...
    3. AlwaysLearning
      - AlwaysLearning replied to Jmartes71's topic in Coping with Celiac Disease
      4

      My only proof

      We feel your pain. It took me 20+ years of regularly going to doctors desperate for answers only to be told there was nothing wrong with me … when I was 20 pounds underweight, suffering from severe nutritional deficiencies, and in a great deal of pain. I had to figure it out for myself. If you're in the U.S., not having an official diagnosis does m...
    4. AlwaysLearning
      - AlwaysLearning replied to Colleen H's topic in Coping with Celiac Disease
      2

      Gluten related ??

      If you're just starting out in being gluten free, I would expect it to take months before you learned enough about hidden sources of gluten before you stopped making major mistakes. Ice cream? Not safe unless they say it is gluten free. Spaghetti sauce? Not safe unless is says gluten-free. Natural ingredients? Who knows what's in there. You pretty much...
    5. Scott Adams
      0

      Häagen-Dazs Chocolate Dark Chocolate Mini Bars Recall Due to Undeclared Wheat and Gluten

  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,077
    • Most Online (within 30 mins)
      7,748
    Deb baker
    Newest Member
    Deb baker
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Colleen H
      Gluten related ??

      By Colleen H · Posted

      Thank you so much for your response  Yes it seems as though things get very painful as time goes on.  I'm not eating gluten as far as I know.  However, I'm not sure of cross contamination.  My system seems to weaken to hidden spices and other possibilities. ???  if cross contamination is possible...I am in a super sensitive mode of celiac disease.. Neuropathy from head to toes
    • Jmartes71
      My only proof

      By Jmartes71 · Posted

      EXACTLY! I was asked yesterday on my LAST video call with Standford and I stated exactly yes absolutely this is why I need the name! One, get proper care, two, not get worse.Im falling apart, stressed out, in pain and just opened email from Stanford stating I was rude ect.I want that video reviewed by higher ups and see if that women still has a job or not.Im saying this because I've been medically screwed and asking for help because bills don't pay itself. This could be malpratice siit but im not good at finding lawyers
    • AlwaysLearning
      My only proof

      By AlwaysLearning · Posted

      We feel your pain. It took me 20+ years of regularly going to doctors desperate for answers only to be told there was nothing wrong with me … when I was 20 pounds underweight, suffering from severe nutritional deficiencies, and in a great deal of pain. I had to figure it out for myself. If you're in the U.S., not having an official diagnosis does mean you can't claim a tax deduction for the extra expense of gluten-free foods. But it can also be a good thing. Pre-existing conditions might be a reason why a health insurance company might reject your application or charge you more money. No official diagnosis means you don't have a pre-existing condition. I really hope you don't live in the U.S. and don't have these challenges. Do you need an official diagnosis for a specific reason? Else, I wouldn't worry about it. As long as you're diligent in remaining gluten free, your body should be healing as much as possible so there isn't much else you could do anyway. And there are plenty of us out here who never got that official diagnosis because we couldn't eat enough gluten to get tested. Now that the IL-2 test is available, I suppose I could take it, but I don't feel the need. Someone else not believing me really isn't my problem as long as I can stay in control of my own food.
    • AlwaysLearning
      Gluten related ??

      By AlwaysLearning · Posted

      If you're just starting out in being gluten free, I would expect it to take months before you learned enough about hidden sources of gluten before you stopped making major mistakes. Ice cream? Not safe unless they say it is gluten free. Spaghetti sauce? Not safe unless is says gluten-free. Natural ingredients? Who knows what's in there. You pretty much need to cook with whole ingredients yourself to avoid it completely. Most gluten-free products should be safe, but while you're in the hypersensitive phase right after going gluten free, you may notice that when something like a microwave meal seems to not be gluten-free … then you find out that it is produced in a shared facility where it can become contaminated. My reactions were much-more severe after going gluten free. The analogy that I use is that you had a whole army of soldiers waiting for some gluten to attack, and now that you took away their target, when the stragglers from the gluten army accidentally wander onto the battlefield, you still have your entire army going out and attacking them. Expect it to take two years before all of the training facilities that were producing your soldiers have fallen into disrepair and are no longer producing soldiers. But that is two years after you stop accidentally glutening yourself. Every time you do eat gluten, another training facility can be built and more soldiers will be waiting to attack. Good luck figuring things out.   
    • Russ H
      KAN-101 Treatment for Coeliac Disease

      By Russ H · Posted

      This treatment looks promising. Its aim is to provoke immune tolerance of gluten, possibly curing the disease. It passed the phase 2 trial with flying colours, and I came across a post on Reddit by one of the study volunteers. Apparently, the results were good enough that the company is applying for fast track approval.  Anokion Announces Positive Symptom Data from its Phase 2 Trial Evaluating KAN-101 for the Treatment of Celiac Disease https://www.reddit.com/r/Celiac/comments/1krx2wh/kan_101_trial_put_on_hold/
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.