Biopsy Results

[blurose112]

After my biopsy I was told the results were inconclusive. I showed extreme inflammation but no damage. When gluten is excluded from my diet my I feel wonderful. It also led me to discover that polypropylene glycol is also a problem. I use no OTC's or prescription medicines. Am I merely sensitive or is a true sprue/celiac condition? Both gluten and polypropylene glycol must be absent from my diet for me to feel well.

[cyclinglady]

What were the results of the complete celiac blood panel and how many biopsies were taken? Were you consuming gluten before the test? If you were gluten light or not consuming gluten, chances are the test will be invalid.

[blurose112]

I went to the only qualifiedcGI specialist in Wichita KS, he decided how to process, yes I made myself so sick eating 3x the gluten he recommended for about month prior to the biopsy. Blood tests mean little and are not good tests for most autoimmune system disorders, I have a autoimmune system disorder heavy family from lupus to psoriasis, rheumatoid arthritis to celiac suffers. I have symptoms of some of the rarer psoriatic conditions but can not a qualified doctor in this area. Some of the more unusual inflammation factors are high but no here seems concerned as the are borderline.

Before this I never liked breads, breakfast cereals etc even as a child I avoided those foods. I prefer fruits vegetables and beans. The possibility of celiac came up while I was being treated for a different disorder and was placed on a low fiber diet which left only foods I had eaten rarely or in small amounts previously. On that physician's suggestion I was scoped and biopsied specifically for celiac. Only DNA testing to my knowledge is definitive for true celiac. I only wanted to learn if anyone had experienced a diagnosis of inconclusive with the doctor noting it could a pre-celiac condition with my medical history etc.

[cyclinglady]

DNA testing is NOT definitive for celiac disease testing. About 30% of the population carry the genes for celiac disease yet only 1% actually go on to develop it. Gene testing helps rule out celiac disease.

Lots of folks here have had a negative biopsy, negative blood tests, and even negative Gene tests and have found relief on a gluten-free diet.

You sound like your family has many Autoimmune diseases, so celiac disease is a possibility. You may be just developing it but I am not a doctor and can not guess at a diagnosis. Most of the folks who are active on this forum have more than one autoimmune disorder, me included.

It is a shame that your qualified GI did not follow standard celiac disease testing. You can research it yourself at The University of Chicago' s celiac website. They list what tests should be ordered. They are one of the leading celiac disease research centers in the US.

I wish you well.