Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

False Positive Vs False Negative. What's More Reliable?


woodyfly

Recommended Posts

woodyfly Rookie

Did a skin allergy test about half a year ago. Tested to be maximum allergic to wheat, medium-mild allergy to chicken, eggs, beer. Wasn't convinced because I've been eating those foods since as long as I can remember and although I do have -some- symptoms that can be tied to an allergy (stuff nose, gas, adult acne, eczema). I did another skin test today at another location and all those allergies were NEGATIVE this time. 

 

So... what's more probable? That the first time resulted in a bunch of false positives or this time they were false negatives?


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



kareng Grand Master

Did a skin allergy test about half a year ago. Tested to be maximum allergic to wheat, medium-mild allergy to chicken, eggs, beer. Wasn't convinced because I've been eating those foods since as long as I can remember and although I do have -some- symptoms that can be tied to an allergy (stuff nose, gas, adult acne, eczema). I did another skin test today at another location and all those allergies were NEGATIVE this time. 

 

So... what's more probable? That the first time resulted in a bunch of false positives or this time they were false negatives?

I moved this to " Other food intolerances" because you are talking about allergy testing, not Celiac testing.

I don't know a lot about allergy testing, but I have heard it is very hard to test for food allergies.

StephanieL Enthusiast

A positive result is 50/50 on accuracy.

 

A negative result is about 90% accurate.

 

it is not recommended that you have allergy testing unless there has been a KNOW reaction because of the unreliable nature of these tests.

 

(This is for IgE mediated allergies via blood or skin testing- NOT alternative testing which has no science to back it up.)

cyclinglady Grand Master

Have you considered getting tested for celiac disease? Celiac disease is not an allergy to wheat. It is an autoimmune response to gluten. There is special celiac blood test.

In my experience I had no intestinal issues, just anemia at the time of my diagnosis and I was consuming lots of wheat daily!

nvsmom Community Regular

Celiac testing is different than allergy testing: false negatives are more common that false positives.  With celiac disease blood testing, the specificity is usually around 95%, which means only 5% of people get a positive result that was not caused by celiac disease, whereas the sensitivity can range between (approximately) 20 to 95%, meaning these tests can miss from 1/20 to 4/5 celiacs.

 

This report (page 12) discusses the celiac disease tests and their reliability: Open Original Shared Link

 

If you get tested for celiac disease, you must be eating gluten in the 8-12 weeks prior to testing or a celiac has a large chance of getting a false negative result.  If you are avoiding wheat and barley (beer) due to an allergy, you'll have to focus on rye, durum, semolina, spelt, kamut or graham flours

 

Best wishes.

kareng Grand Master

Celiac testing is different than allergy testing: false negatives are more common that false positives. With celiac disease blood testing, the specificity is usually around 95%, which means only 5% of people get a positive result that was not caused by celiac disease, whereas the sensitivity can range between (approximately) 20 to 95%, meaning these tests can miss from 1/20 to 4/5 celiacs.

This report (page 12) discusses the celiac disease tests and their reliability: Open Original Shared Link

If you get tested for celiac disease, you must be eating gluten in the 8-12 weeks prior to testing or a celiac has a large chance of getting a false negative result. If you are avoiding wheat and barley (beer) due to an allergy, you'll have to focus on rye, durum, semolina, spelt, kamut or graham flours

Best wishes.

Actually, durum, semolina, spelt, kaput and graham are actually wheat. They are just a slightly different version of wheat. Like a Granny Smith is a bit different version of an apple from a Red Delicious.
nvsmom Community Regular

Good point!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Oliverg posted a topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      0

      Glutened

    2. - knitty kitty replied to xxnonamexx's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      19

      My journey is it gluten or fiber?

    3. - xxnonamexx replied to xxnonamexx's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      19

      My journey is it gluten or fiber?

    4. - olivia11 replied to olivia11's topic in Gluten-Free Foods, Products, Shopping & Medications
      2

      suggest gluten free food

    5. - knitty kitty replied to Roses8721's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      16

      GI DX celiac despite neg serology and no biopsy

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      132,762
    • Most Online (within 30 mins)
      7,748

    Nana 75
    Newest Member
    Nana 75
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • Oliverg
      Hi all I’ve been celiac for 4 years now, I’ve done pretty well to avoid it thus far. Last night I took the wrong pizza out of the freezer and ate the whole lot!! The non gluten and gluten pizza boxes are both very similar.   2 hours later I was throwing up violently on my hands and knees over the loo.  .horrendous stomach pains,  My hair was wet from sweat every part of my body was wet. What an awful experience, just had a bad headache today  fortunately.    Is their any products/pills anyone takes if they have realised they have just been glutened to make the symptoms a little less worse.  thanks  
    • knitty kitty
      Yes, do take your B Complex with Benfotiamine or Thiamax.  Thiamine interacts with each of the other B vitamins in the B Complex to make energy and enzymes, so best to take them together earlier in your day.  Taking them too close to bedtime can keep you too energetic to go to sleep.   The Life Extension Benfotiamine with Thiamine is Benfotiamine and Thiamine Hydrochloride, another form of thiamine the body likes.  The Thiamine HCl just helps the Benfotiamine work better.   Read the label for how many milligrams are in them.  The Mega Benfotiamine is 250 mgs.  Another Benfothiamine has 100 mgs.  You might want to start with the 100 mg.    I like to take Thiamax in the morning with a B Complex at breakfast.  I take the Benfotiamine with another meal.  You can take your multivitamin with Benfotiamine at lunch.   Add a magnesium supplement, too.  Thiamine needs magnesium to make some important enzymes.  Life Extension makes Neuro-Mag, Magnesium Threonate, which is really beneficial.  (Don't take Magnesium Oxide.  It's not absorbed well, instead it pulls water into the digestive tract and is used to relieve constipation.)  I'm not a big fan of multivitamins because they don't always dissolve well in our intestines, and give people a false sense of security.  (There's videos on how to test how well your multivitamin dissolves.).  Multivitamins don't prevent deficiencies and aren't strong enough to correct deficiencies.   I'm happy you are trying Thiamax and Benfotiamine!  Keep us posted on your progress!  I'm happy to answer any questions you may have.  
    • xxnonamexx
      I looked further into Thiamax Vitamin B1 by objective nutrients and read all the great reviews. I think I will give this a try. I noticed only possible side affect is possibly the first week so body adjusts. Life Extensions carries Benfotiamine with Thiamine and the mega one you mentioned. Not sure if both in one is better or seperate. some reviews state a laxative affect as side affect. SHould I take with my super B complex or just these 2 and multivitamin? I will do further research but I appreciate the wonderful explanation you provided on Thiamine.
    • olivia11
      Thanks I am mostly looking for everyday staples and easy meal ideas nothing too specialty if possible.
    • knitty kitty
      There are other Celiac genes. HLA DQ 2 and HLA DQ 8 show up in people from Northern European descent.   People of Mediterranean descent have HLA DQ 7.  People of Asian descent have HLA DQ 9.   There's other Indigenous populations that have other HLA genes that code for Celiac disease.   Are you still having symptoms?   What do you include in your diet?  Are you vegetarian? Are you taking any prescription medication?  Omeprazole?  Metformin?   Do you have anemia?  Thyroid problems? Are you taking any vitamins or herbal supplements?  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.