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Autoimmunity and TTG

Jenny0409

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Jenny0409 Rookie
Jenny0409
Posted

So recently I had a really high positive on the TTG IGA leading my doctor to believe I have Celiac. For a host of reasons, for the time being, I'm not going through with the endoscopy. I have been completely gluten free from day I got my results. I have no intention of going back on gluten. I had a previous diagnosis of Graves Disease(Hyperthyroidism) last year and in December had my thyroid completely removed. The doctor tested for Celiac because of my ongoing symptoms such as intense muscle spasm/cramps, bone pain, low calcium, low Vitamin D, the list goes on. Anyway, in conjunction with the Celiac panel he decided to have me to an ACTH. I learned that test is for Addisions and other Adrenal issues. My questions is, could the presence of Addisions cause a false positive on the TTG IGA? I feel sure I have Celiac but I'm not sure about Addision. Are they often found together? If so, that would put me at a grand total of 3 autoimmune disorders. Is that common?

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Scott Adams Grand Master
Scott Adams
Posted

I've not heard of Addison's causing a false positive on any celiac disease screening results. 

 

nvsmom Community Regular
nvsmom
Posted

I doubt it too. 95% of the time a positive ttG IgA is caused by celiac disease. The other 5% of the time, a weak positive is caused by hashimoto's, liver disease, diabetes, crohn's, colitis, or a serious infection.  I would say you probably have celiac disease.  :(

Jenny0409 Rookie
Jenny0409
Posted
  • Author

I think so too. However, my only concern was if the antibodies from having had Graves could still be floating around causing a false positive. But my positive TTG test was not a weak positive it was a very strong positive so it's likely that it is Celiac I suppose. 

nvsmom Community Regular
nvsmom
Posted

Yeah... :(  Usually false positive are pretty weak.

I have celiac disease, Hashi's, and ITP (and I still suspect MCTD or something similar).  My ttG IgA took over a year to get back into normal, and then it was still a high normal for another year. My Hashi's might have kept it up a bit, and even now it is about a 5 out of 14 - still not super low.

You'll find many of us have multiple issues that slows recovery somewhat.  You're in good company.  ;)

Jenny0409 Rookie
Jenny0409
Posted
  • Author

The scale for my TTG IgA test was 0-3 negative, 4-10 weak positive, and above 10 positive. I was a 16. Guess that is pretty positive lol The denial is something I didn't expect. I know it's stupid to feel like maybe I don't have it when all signs point to a big fat yes. I know intellectually that I have to stay Gluten free and I'm doing very well on the gluten-free diet if I do say so myself. I slipped once (damn you pumpkin spice lattee) and I paid for it with two days of muscle cramps, bone pain, brain fog, and depression. That was enough to keep me away from that poison forever let me tell you. I though I was home free at first because the symptoms didn't hit until the next day. They were so evident that even my husband noticed the dramatic shift in my physical state and attitude.

nvsmom Community Regular
nvsmom
Posted

Yep, that's pretty positive. Five times above normal.  ;)

Ah yes, evil pumpkin spice latte....Well, on the bright side, it is often easier to stay away from risky cc situations when the symptoms are obvious.  I think it can be tough to stay gluten-free when you don't feel this disease.  KWIM?

Hang in there.  You'll have the hang of this diet before Xmas rolls around.  Hopefully you'll be really noticing improvements by then too.  :)

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