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TTG negative. Have symptoms. What next?

minivan

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minivan Newbie
minivan
Posted

Hi all,

looking for guidance or information.  I had the private md labs celiac panel run.  Results came back negative for celiac.

my symptoms are:

bloating

constipation

aches in old injury sites

sinusitis

These symptoms are very reliable.  I have been doing various eliminations for about 4 years.  They occur after a single high dose of flour, eg a lot of pizza, or after 3 consecutive days of smaller doses. Thanks in advance.

jesse

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minivan Newbie
minivan
Posted
  • Author

I read the FAQ and discussed with an MD.  It seems that I didn't challenge myself with enough gluten exposure to make the celiac panel which I pasted above give accurate results.

As a side note, it's very interesting that I could have enough exposure to elicit symptoms and yet not have enough of a response to have a valid test result.

CherylS Apprentice
CherylS
Posted

Hello,

I'm new here too, I'm not getting tested for another week to make sure I eat enough gluten before my test.  I just wanted to say that I"m glad you are getting retested. It sounds like you have a great doctor who listens to you.  

nvsmom Community Regular
nvsmom
Posted

It could be celiac, especially if only one test like the tTg IgA was run, or it could be non-celiac gluten sensitivity (NCGS) which has the same symptoms as celiac disease.

Before doing more testing you need to be eating the equivalent of 1-2 slices of bread per day in the 2-3 months prior to testing.  You're right that if gluten levels are too low, some celiacs will test negative. This is especially common in the early years of the disease.  The deamnated gliadin peptides (DGP IgA and DGP IgG) are best at detecting early celiac disease.

Best wishes.

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