Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Weak Positive DGP IgG test


Sissi123

Recommended Posts

Sissi123 Newbie

Hi, I am 25 years old and in the last couple of months I was feeling bed: mainly  I was very tired, I had diarrhea, bloating and two symmetric big red and itchy spots in my legs. My brother and my cousin are celiac, so I did a first test (Xeliac test, based on Transglutaminase IgA and IgG), which was positive.  So I went to the doctor for the blood tests. The only results out of the range are Total IgA (0.5 with normal range 0.7-1.00) and DGP IgG (1.15 with normal range 0 - 1), while Transglutaminase IgA and DGP IgA were normal (he didn't check Transglutaminase IgG).  The first one is comparable to the one of my brother, who has also low IgA.

After three weeks of diet (I started right after the blood tests, as my doctor suggested me) I am feeling a bit better. The doctor now told me to eat gluten again for further tests, but I am not sure I want to feel bad again, since only  in the last few days the situation started changing after a long while. 

What do you suggest? Is it possible that my problems are really related to celiac disease or gluten sensibility? Are there other causes that can turn DGP IgG to be weakly positive?

Thanks for your help.

 

 

 


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



GFinDC Veteran

Hi Sissi,

Your doctor screwed up.  They never should have you go off gluten until all testing is done.  I don't know of anything else that can make DGP IgG positive besides celiac disease.  We always tell people not to go gluten-free until all testing is done.  If you are starting to feel better, that is more evidence that gluten is a problem for you.

Welcome to the forum Sissi! :)

 

 

Sissi123 Newbie

Thanks a lot for your answer and your "Welcome".

Unfortunately I trusted my doctor.

Thanks again!

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - cristiana replied to colinukcoeliac's topic in Gluten-Free Restaurants
      10

      What should I expect from a UK restaurant advertising / offering "Gluten Free" food

    2. - cristiana replied to hjayne19's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      34

      Insomnia help

    3. - cristiana replied to colinukcoeliac's topic in Gluten-Free Restaurants
      10

      What should I expect from a UK restaurant advertising / offering "Gluten Free" food

    4. - melthebell replied to melthebell's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      2

      Persistent isolated high DGP-IGG in child despite gluten-free diet

    5. - trents replied to melthebell's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      2

      Persistent isolated high DGP-IGG in child despite gluten-free diet

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,498
    • Most Online (within 30 mins)
      7,748

    genliu
    Newest Member
    genliu
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Who's Online (See full list)

    • There are no registered users currently online
  • Upcoming Events

  • Posts

    • cristiana
      Re: Michelin star.  To give an example, the Ritz Hotel in London has two Michelin stars.   Here's another article about Michelin stars - from our own archive.  
    • cristiana
      Very helpful @knitty kitty.  Thank you.  I am trying to remember what vitamin so alarmed my GP and I have a feeling it was A or E.  I remember reading the pills contained well over the 100 per cent RDA of whatever the vitamin was. One thing I'd love to ask you that has always intrigued me.  One day when my anxiety was completely through the roof.  I 'felt the fear and did it anyway' - a phrase other anxiety sufferers may be aware of, which I found a powerful tool in my recovery -  and visited a friend's house, even though I felt so wretched.  For some reason I craved milk and drank two whole pints of milk in quick succession while I was with her - to this day I can't think why, because I don't usually drink milk 'neat' - I like it in tea or coffee, or hot chocolate.  But I distinctly remember within a couple of hours feeling absolutely fine again for quite a while.  I've often wondered was it down to this milk, which I've since understood contains quite decent levels of B12.  Would that have really worked so fast?    
    • cristiana
      @trents  Good question.  We are strict at home, although I have to admit I've eating the odd chocolate at Christmas that turned out to have been made in a shared facility.  But that  is very unusual for me, and I had my last blood test before Christmas anyway.  Therefore I have concluded that eating out must be the issue.  But I'll let you know in September when I have my next blood tests done.  😊  
    • melthebell
      Thanks very much for taking the time to write this. I have been pretty worried so appreciate reading any advice. Yes, the endoscopy will include a biopsy, and we have hopefully found a good pediatric gastro to guide us through it all.  Will also run the HLA typing - I have the swabs ready to go.
    • trents
      Welcome to the celiac.com community, @melthebell! I certainly would have a biopsy repeated as it has been 5 years since the first one. You mentioned he was scheduled for an endoscopy but make sure a biopsy is also done. It's possible he, like you are, is a "silent" celiac where the damage to the intestinal mucosa happens very slowly and can take years to manifest to the point of being detectable and where symptoms are minimal or absent. At 10 years old, his immune system may not be mature enough het to trigger the usual IGA responses that the IGA celiac tests are designed to detect.  I would also have genetic testing done to confirm that he has or doesn't have the potential to develop celiac disease. The genetic profile can also offer insight into the type of celiac disease a person will develop if they ever convert from latent to active. Take a look at table 2 under the section "Types of Celiac Disease" in the article found in this link: https://pmc.ncbi.nlm.nih.gov/articles/PMC9980758/  Genetic testing is available from 3rd party labs. I think you just have to send in a cheek swab sample.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.