Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Anyone gene savvy and can decode?

JelizabethP

Recommended Posts

JelizabethP Newbie
JelizabethP
Posted

Hi everyone!

im sure questions like this are asked quite a bit. I've been having GI issues as long as I can remember. I've had a few tests but then just gave up and decided it was just IBS. 

I recently paid to have my ancestry genetics translated into health risks, etc. 

I cannot for the life of me figure out if this could be a gene associated with celiac or not. If it turns out to be I will mention to my doctor and hopefully solve these awful GI problems! :) if it's not then I'll keep calling it IBS. 

I will insert screenshots as well as type the data. 

It seems to list "gene" as HLA-DQA1 and then it looks like I inherited 2 alleles which are both HLA-DRB1*0301

When I google "genes associated with celiac" other genes come up and this either appears to be in a different format (maybe others are shortened versions? Or unrelated?) 

It lists Lupus and celiac disease as concerns... I would love to have a real answer (or at least new path for my doctor to investigate!) to these stomach issues I've always had but if it's not celiac I suppose I can settle with IBS a bit longer! :) 

 

Thanks everyone!!! 

(I was particularly confused by the "gene" vs alleles part as one looked like it could be celiac related and the other I had no idea!) 

 

IMG_0616.PNG

IMG_0617.PNG

IMG_0618.PNG

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


cyclinglady Grand Master
cyclinglady
Posted
1 hour ago, JelizabethP said:

Hi everyone!

im sure questions like this are asked quite a bit. I've been having GI issues as long as I can remember. I've had a few tests but then just gave up and decided it was just IBS. 

I recently paid to have my ancestry genetics translated into health risks, etc. 

I cannot for the life of me figure out if this could be a gene associated with celiac or not. If it turns out to be I will mention to my doctor and hopefully solve these awful GI problems! :) if it's not then I'll keep calling it IBS. 

I will insert screenshots as well as type the data. 

It seems to list "gene" as HLA-DQA1 and then it looks like I inherited 2 alleles which are both HLA-DRB1*0301

When I google "genes associated with celiac" other genes come up and this either appears to be in a different format (maybe others are shortened versions? Or unrelated?) 

It lists Lupus and celiac disease as concerns... I would love to have a real answer (or at least new path for my doctor to investigate!) to these stomach issues I've always had but if it's not celiac I suppose I can settle with IBS a bit longer! :) 

 

Thanks everyone!!! 

(I was particularly confused by the "gene" vs alleles part as one looked like it could be celiac related and the other I had no idea!) 

 

IMG_0616.PNG

IMG_0617.PNG

IMG_0618.PNG

I am not a genetic expert, but the reality is that some 30% of the population has the genes that can develop into celiac disease (rare about 1% or so).  Genetic testing is used to rule out celiac disease, not to diagnose it.  You should ask your doctor to order a complete celiac blood panel.  Learn more about testing from the University of Chicago:

Open Original Shared Link

I personally would never take an IBS diagnosis which in my mind means, "I be Stumped!"  Not saying you have celiac disease, but there is something causing your IBS symptoms.  Keep advocating for your health.  ?

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. trents
      - trents replied to GlutenFreeChef's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      9

      Blood Test for Celiac wheat type matters?

      Wheatwacked, are you speaking of the use of potassium bromide and and azodicarbonamide as dough modifiers being controlling factor for what? Do you refer to celiac reactions to gluten or thyroid disease, kidney disease, GI cancers?
    2. Scott Adams
      - Scott Adams replied to GlutenFreeChef's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      9

      Blood Test for Celiac wheat type matters?

      Excess iodine supplements can cause significant health issues, primarily disrupting thyroid function. My daughter has issues with even small amounts of dietary iodine. While iodine is essential for thyroid hormone production, consistently consuming amounts far above the tolerable upper limit (1,100 mcg/day for adults) from high-dose supplements can trigger...
    3. Wheatwacked
      - Wheatwacked replied to GlutenFreeChef's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      9

      Blood Test for Celiac wheat type matters?

      In Europe they have banned several dough modifiers potassium bromide and and azodicarbonamide. Both linked to cancers. Studies have linked potassium bromide to kidney, thyroid, and gastrointestinal cancers. A ban on it in goes into effect in California in 2027. I suspect this, more than a specific strain of wheat to be controlling factor. Sourdough...
    4. jenniber
      - jenniber replied to tiffanygosci's topic in Introduce Yourself / Share Stuff
      5

      Celiac support is hard to find

      same! how amazing you have a friend who has celiac disease. i find myself wishing i had someone to talk about it with other than my partner (who has been so supportive regardless)
    5. RMJ
      - RMJ replied to TheDHhurts's topic in Gluten-Free Foods, Products, Shopping & Medications
      1

      need help understanding testing result for Naked Nutrition Creatine please

      They don’t give a sample size (serving size is different from sample size) so it is hard to tell just what the result means. However, the way the result is presented does look like it is below the limit of what their test can measure, so that is good.
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,122
    • Most Online (within 30 mins)
      7,748
    Sarer
    Newest Member
    Sarer
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Who's Online (See full list)

  • Upcoming Events

  • Posts

    • trents
      Blood Test for Celiac wheat type matters?

      By trents · Posted

      Wheatwacked, are you speaking of the use of potassium bromide and and azodicarbonamide as dough modifiers being controlling factor for what? Do you refer to celiac reactions to gluten or thyroid disease, kidney disease, GI cancers? 
    • Scott Adams
      Blood Test for Celiac wheat type matters?

      By Scott Adams · Posted

      Excess iodine supplements can cause significant health issues, primarily disrupting thyroid function. My daughter has issues with even small amounts of dietary iodine. While iodine is essential for thyroid hormone production, consistently consuming amounts far above the tolerable upper limit (1,100 mcg/day for adults) from high-dose supplements can trigger both hyperthyroidism or hypothyroidism, worsen autoimmune thyroid diseases like Hashimoto's, and lead to goiter. Other side effects include gastrointestinal distress. The risk is highest for individuals with pre-existing thyroid conditions, and while dietary iodine rarely reaches toxic levels, unsupervised high-dose supplementation is dangerous and should only be undertaken with medical guidance to avoid serious complications. It's best to check with your doctor before supplementing iodine.
    • Wheatwacked
      Blood Test for Celiac wheat type matters?

      By Wheatwacked · Posted

      In Europe they have banned several dough modifiers potassium bromide and and azodicarbonamide.  Both linked to cancers.  Studies have linked potassium bromide to kidney, thyroid, and gastrointestinal cancers.  A ban on it in goes into effect in California in 2027. I suspect this, more than a specific strain of wheat to be controlling factor.  Sourdough natural fermentation conditions the dough without chemicals. Iodine was used in the US as a dough modifier until the 1970s. Since then iodine intake in the US dropped 50%.  Iodine is essential for thyroid hormones.  Thyroid hormone use for hypothyroidism has doubled in the United States from 1997 to 2016.   Clinical Thyroidology® for the Public In the UK, incidently, prescriptions for the thyroid hormone levothyroxine have increased by more than 12 million in a decade.  The Royal Pharmaceutical Society's official journal Standard thyroid tests will not show insufficient iodine intake.  Iodine 24 Hour Urine Test measures iodine excretion over a full day to evaluate iodine status and thyroid health. 75 year old male.  I tried adding seaweed into my diet and did get improvement in healing, muscle tone, skin; but in was not enough and I could not sustain it in my diet at the level intake I needed.  So I supplement 600 mcg Liquid Iodine (RDA 150 to 1000 mcg) per day.  It has turbocharged my recovery from 63 years of undiagnosed celiac disease.  Improvement in healing a non-healing sebaceous cyst. brain fog, vision, hair, skin, nails. Some with dermatitis herpetiformis celiac disease experience exacerbation of the rash with iodine. The Wolff-Chaikoff Effect Crying Wolf?
    • jenniber
      Celiac support is hard to find

      By jenniber · Posted

      same! how amazing you have a friend who has celiac disease. i find myself wishing i had someone to talk about it with other than my partner (who has been so supportive regardless)
    • RMJ
      need help understanding testing result for Naked Nutrition Creatine please

      By RMJ · Posted

      They don’t give a sample size (serving size is different from sample size) so it is hard to tell just what the result means.  However, the way the result is presented  does look like it is below the limit of what their test can measure, so that is good.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.