Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Is Zenpep enzyme supplement truly gluten free?


GrayGluten

Recommended Posts

GrayGluten Newbie

Hello,

Apologies in advance if this question has already been answered, but I can't seem to find an exact answer.

Recently diagnosed Celiac after about six months of symptoms, tests and stress. Finally went 100% gluten free over a month ago (food, medications, cosmetics) and am finally just beginning to feel and see some small improvements consistently. 

For continued malnutrition and still-persistent bowel issues, my doctor recently prescribed me Zenpep enzyme supplement (25,000 lipase USP units; delayed release capsules) and within a couple of hours of taking it for the first time I've been experiencing what feels like light glutened side effects for me so far - dull headache, slight brain fog, mild abdominal pains. I'm curious: Is Zenpep gluten free? If these symptoms are normal or expected when first beginning to take Zenpep or supplements like it, I'm willing to give it some time, but if not, it's understandably defeating as I was finally on a good symptom-free run.

I've reviewed all of the active and inactive ingredients on Zenpep.com, and though it's not officially labeled as such, it appears to be gluten-free. However, am I missing something? I'm also awaiting a response from the manufacturer.

If Zenpep is gluten free, then would there be any other common reasons or predispositions that may cause this reaction? Can taking pancreatic enzymes not always be a good idea for Celiacs?

Hoping for any anecdotes of people who are Celiac or severely intolerant and have taken Zenpep.

Sorry for long post - thank you so much!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Ennis-TX Grand Master
10 hours ago, GrayGluten said:

Hello,

First time poster, long-time reader. Apologies in advance if this question has already been answered, but I can't seem to find an exact answer.

Recently diagnosed Celiac after about six months of symptoms, tests and stress. Finally went 100% gluten free over a month ago (food, medications, cosmetics, etc.) and am finally just beginning to feel and see some small improvements consistently. 

For continued malnutrition and still-persistent bowel issues, my doctor recently prescribed me Zenpep enzyme supplement (25,000 lipase USP units; delayed release capsules) and within a couple of hours of taking it for the first time I've been experiencing what feels like light glutened side effects for me so far - dull headache, slight brain fog, mild abdominal pains. I'm curious: Is Zenpep is gluten free? If these symptoms are normal or expected when first beginning to take Zenpep or supplements like it, I'm willing to give it some time, but if not, it's understandably defeating as I was finally on a good symptom-free run.

I've reviewed all of the active and inactive ingredients on Zenpep.com, and though it's not officially labeled as such, it "seems" to be gluten-free from what I can research. However, not being as wise or knowledgeable as so many on this forum yet, am I missing something?

If Zenpep is in fact gluten-free, then would there be any other common reasons or predispositions that may cause this reaction? Can taking pancreatic enzymes not always be a good idea for Celiacs?

Hoping for any anecdotes of people who are Celiac or severely intolerant and have taken Zenpep.

Sorry for long post - thank you so much!

Unsure exactly...but why just one enzyme? I take Jarrow enzymes plus. Much better line up in my opinion, I also take extra bromeline on high protein meals, and sometimes papaya enzymes after a meal.

GrayGluten Newbie
7 hours ago, Ennis_TX said:

Unsure exactly...but why just one enzyme? I take Jarrow enzymes plus. Much better line up in my opinion, I also take extra bromeline on high protein meals, and sometimes papaya enzymes after a meal.

Zenpep is actually a combination of Lipase, Protease and Amylase. Should have clarified - dosage on package is based on Lipase units for some reason.

It's what my doctor recommended, but plan to revisit next appointment.

Curious if there are any similar, recommended OTC enzyme brands or prescription alternatives that may be certified gluten free?

Ennis-TX Grand Master
3 minutes ago, GrayGluten said:

Zenpep is actually a combination of Lipase, Protease and Amylase. Should have clarified - dosage on package is based on Lipase units for some reason.

It's what my doctor recommended, but plan to revisit next appointment.


Curious if there are any similar, recommended OTC enzyme brands or prescription alternatives that may be certified gluten free?

Extra 15% off this month on jarrow with code look at the enzymes plus. I mentioned. might as well use them to stock up on anything else you might need.


Open Original Shared Link

Archived

This topic is now archived and is closed to further replies.

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,353
    • Most Online (within 30 mins)
      7,748

    ace14219
    Newest Member
    ace14219
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • SilkieFairy
      It could be a fructan intolerance? How do you do with dates?  https://www.dietvsdisease.org/sorry-your-gluten-sensitivity-is-actually-a-fructan-intolerance/
    • Lkg5
      Thank’s for addressing the issue of mushrooms.  I was under the impression that only wild mushrooms were gluten-free.  Have been avoiding cultivated mushrooms for years. Also, the issue of smoked food was informative.  In France last year, where there is hardly any prepared take-out food that is gluten-free, I tried smoked chicken.  Major mistake!
    • catnapt
      my IGG is 815 IGA 203  but tTG-Iga is   <0.4!!!!!!!!!!!!!   oh my god- 13 days of agony and the test is negative?  I don't even know what to do next. There zero doubt in my mind that I have an issue with wheat and probably more so with gluten as symptoms are dramatically worse the more gluten a product has   I am going to write up the history of my issues for the past few years and start a food/symptom diary to bring with me to the GI doctor in March.   I googled like crazy to try to find out what other things might cause these symptoms and the only thing that truly fits besides celiac is NCGS   but I guess there are some other things I maybe should be tested for ...? like SIBO?   I will continue to eliminate any foods that cause me distress (as I have been doing for the past couple of years) and try to keep a record. Can anyone recommend an app or some form or something that would simplify this? I have a very full and busy life and taking the time to write out each symptom name in full would be tedious and time consuming- some sort of page with columns to check off would be ideal. I am not at all tech savvy so that's not something I can make myself ... I'm hoping there's some thing out there that I can just download and print out   do I give up on testing for celiac with such a low number? I am 70 yrs old I have been almost completely off gluten for the most part for about 2 yrs. I had a meal of vital wheat gluten vegan roast,  rolls and stuffing made from home baked bread and an apple pie- and had the worst pain and gas and bloating and odd rumblings in my gut etc - almost went to the ER it was so bad. I was thinking, since I'm spilling a lot of calcium in my urine, that perhaps this was a kidney stone (never had one before but there's always that first time, right?)    Saw my endo on Jan 20th and after hearing the story about the symptoms from eating that holiday meal, she suggested doing a gluten challenge. She said 2 weeks was fine- she said stopping it in the middle if symptoms got bad was fine- In the meantime I'd read that 2 weeks was not enough- called and argued with the nurse about this, but ultimately decided to stop the gluten on the 13th day and get the test done because I was in too much pain and almost suicidal and knew I could not continue.   so.............. that's where I am now I have had no bread since Sunday. I did have some rolled oats today and had some gas and bloating afterwards I did have some wheat germ in a smoothie on Tuesday and had a stomach ache later that night.   but overall I feel so much better! all the joint pain is gone! the nausea is gone. The stomach pain and gas and bloating are going away. Still a bit gassy but no more of that horrible odor. wow, that would clear a room if I was out in public!  I see a GI nurse March 4th  I hope she'll be able to help sort this out! can you think of what my next steps might be?
    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.