What does this mean?

[GlitterPants8]

My daughter had positive blood tests and so I had my son tested. All his tests were negative except Gliadin (deamidated) which was 15.9, a positive is over 15. Does that mean I don't have to worry or would you push for more testing? 

[Scott Adams]

A positive deamidated gliadin antibodies (DMG) test means that your son also likely has celiac disease, and will need to go gluten-free. His doctor may want to run more tests, but given that his sister has been diagnosed with celiac disease, his doctor may be able to make the diagnosis without doing an endoscopy. 

https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/89029 
"Positive test results for deamidated gliadin antibodies, IgA or IgG, are consistent with the diagnosis of celiac disease."

Be sure to discuss this with his doctor.

[GlitterPants8]

2 hours ago, Scott Adams said:

A positive deamidated gliadin antibodies (DMG) test means that your son also likely has celiac disease, and will need to go gluten-free. His doctor may want to run more tests, but given that his sister has been diagnosed with celiac disease, his doctor may be able to make the diagnosis without doing an endoscopy. 

https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/89029 
"Positive test results for deamidated gliadin antibodies, IgA or IgG, are consistent with the diagnosis of celiac disease."

Be sure to discuss this with his doctor.

Thanks. Even though everything else was in normal range? 

Obviously I'll talk to his Dr., but he happens to be on vacation right now so I'll have to wait. 

It would be a crushing diagnosis for him as he thinks bread is life. 

 

 

[Scott Adams]

Unfortunately this single positive ought to be enough to make a diagnosis, but it's possible his doctor will want to also do an endoscopy to confirm it. For kids the DMG test seems to more accurate than the others, but if you have those other results feel free to share them with the reference range.

[GlitterPants8]

18 hours ago, Scott Adams said:

Unfortunately this single positive ought to be enough to make a diagnosis, but it's possible his doctor will want to also do an endoscopy to confirm it. For kids the DMG test seems to more accurate than the others, but if you have those other results feel free to share them with the reference range.

Here is a screen shot of the results. Hopefully. You should see everything else is negative and his Iga seems to be in normal range. Unless I'm reading it wrong. 

[Scott Adams]

In children the DMG test is the most reliable, and it only takes on positive result to indicate celiac disease...all results do not need to be positve.