Gluten panels higher after retesting

[Sheilatejeda]

My sons been on a . Gluten free diet for 6 months after being diagnosed with celiac, not the usual symptoms , his presented with rect prolapses every time he poops, anyway he had retesting done for the celiac panels and the gliadin ab deamid. IgG came back one point worse, he went from 36 to 37  value..normal being <15.. I’m so confused because as far as I know I’ve cut gluten out of his diet completely.. his globulin level also came back lower than the first blood test. And when he had the biopsy of his small intestine it came back with neutrophil abnormalities but not damaged vili , so that’s also confusing because the doctor still diagnosed him with celiac.. there’s no improvement with his prolapses, and don’t know what to do or change anymore for him .. any help would be very appreciated 

[trents]

Welcome to the forum, Sheilatejeda!

How old is your son? And would you be willing to post the complete results of the antibody testing that was done on your son? Were there any IGA tests run, particularrly a tTG-IGA test? What was the specific IGG test that was run?

You say his globulin level came back lower than the first test. Do you refer to total IGA?

This might help you understand my questions: https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/

Also, is our son still consuming dairy and oats? For some celiacs these two foods can mimic the inflammation caused by gluten.

[RMJ]

I would not call 37 significantly higher than 36.  If a lab ran the same blood sample 10 times they would sometimes get 36 and sometimes 37.

Even so, it is frustrating that the level hasn’t decreased.  Sometimes it can be difficult to find the hidden gluten that someone is exposed to.

[Sheilatejeda]

hi yes so he just turned 5 , this all started march of 2021 the initial prolapse then losing weight ,anemia… so these are the tests with results from three days ago.

TTG IgA: <0.5

TTG IgG: <0.8

Gliadin AB DEamid .IgA : 0

Gliadin AB Deamid. IgG: 37 

Albumin globulin ratio: 2.9 H

Bun/creatinine ratio: 33H 

Globulin: 1.6 L

Those are the ones that came back abnormal. 

2 hours ago, trents said:

Welcome to the forum, Sheilatejeda!

How old is your son? And would you be willing to post the complete results of the antibody testing that was done on your son? Were there any IGA tests run, particularrly a tTG-IGA test? What was the specific IGG test that was run?

You say his globulin level came back lower than the first test. Do you refer to total IGA?

This might help you understand my questions: https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/

Also, is our son still consuming dairy and oats? For some celiacs these two foods can mimic the inflammation caused by gluten.

Also yes he is consuming diary but not oats, maybe oats in the occasional gluten-free product that includes it in its recipes . But he does consume diary on a daily basis 

[trents]

Looks like your son has a serum protein component that is low (globulin). This can be related to kidney disease. Bun/creatinine ratio is high. Bun and creatinine also have to do with kidney function. Has your physician discussed this with you?

As far as celiac disease goes, he does have one antibody marker that is high, Gliadin AB Deamid. This test is often run when total IGA is low and the TTG Iga is low. But there is not damage to the villi. Might be celiac disease caught in the early stages but there may be other things going on there not related to gluten issues.

[Sheilatejeda]

11 minutes ago, trents said:

Looks like your son has a serum protein component that is low (globulin). This can be related to kidney disease. Bun/creatinine ratio is high. Bun and creatinine also have to do with kidney function. Has your physician discussed this with you?

As far as celiac disease goes, he does have one antibody marker that is high, Gliadin AB Deamid. This test is often run when total IGA is low and the TTG Iga is low. But there is not damage to the villi. Might be celiac disease caught in the early stages but there may be other things going on there not related to gluten issues.

He hasn’t brought up anything to do with kidney disease so I might bring that up when I speak to him again, the bun creatinine ratio did get lower the initial test showed a level of 60 and it’s now at 33 but still high 

[Wheatwacked]

Home made chili with beans. I mix small red, chick pea and pinto so the mouth feel doesn't get boring. Soak the beans overnight to remove the lectins. Full of healthy nutrition. A five year old should get 10 - 15 grams of fiber and this mix has 15 grams fiber per 100 grams uncooked beans. The fiber helps with "pushing" so may help with the prolapse and the fiber feeds the good gut bacteria. Try different flavorings instead of just commercial chili powder.

[trents]

I'm not sure a 5 year old would take to chili with beans.

[Wheatwacked]

10 Chili Recipes Kids Will Actually Love

https://www.thekitchn.com/kid-friendly-chili-261994

[Sheilatejeda]

3 hours ago, trents said:

I'm not sure a 5 year old would take to chili with beans.

He is very picky to top it off lol

[knitty kitty]

15 hours ago, Sheilatejeda said:

My sons been on a . Gluten free diet for 6 months after being diagnosed with celiac, not the usual symptoms , his presented with rect prolapses every time he poops, anyway he had retesting done for the celiac panels and the gliadin ab deamid. IgG came back one point worse, he went from 36 to 37  value..normal being <15.. I’m so confused because as far as I know I’ve cut gluten out of his diet completely.. his globulin level also came back lower than the first blood test. And when he had the biopsy of his small intestine it came back with neutrophil abnormalities but not damaged vili , so that’s also confusing because the doctor still diagnosed him with celiac.. there’s no improvement with his prolapses, and don’t know what to do or change anymore for him .. any help would be very appreciated 

Has your son been checked for vitamin and mineral deficiencies?

Rectal prolapse has been associated with low Vitamin D resulting in weak pelvic floor muscles...

Vitamin D is also integral to regulating and calming the immune system.  

Thiamine deficiency has been associated with constipation.

Your doctor is really on his toes about the Celiac diagnosis.  Neutrophils influx into areas being damaged and the neutrophils call in T-cells and the autoimmune response really takes off from there including damage to the villi.  Good fortune it was caught so early.

Consultation with a nutritionist would be most beneficial.  A nutritionist familiar with Celiac will help you discover if gluten is slipping into your son's diet somewhere.  (Are soaps and toiletries all gluten free?)  

Some Celiacs react to oats, corn, and soy.  Dairy is known to cause continuing inflammation and damage to the small intestine.  Have you tried cutting these out of your son's diet?  

Does your son eat much processed gluten free facsimile foods?  While wheat flour products are required by law to be enriched with vitamins lost in processing, gluten free facsimile foods are not required to be enriched.  Does your son eat a diet high in carbohydrates like these?   Diets high in carbohydrates require more Thiamine than they may contain to turn the carbohydrates into energy for the body to function properly.  

The AutoImmune Protocol diet was developed by a Celiac doctor with Celiac children.  The AIP diet has been scientifically shown to promote healing.  

A gluten free diet can be lacking in certain vitamins and minerals.  A diet full of nutrient rich foods and not empty calories is beneficial.  Supplementing with vitamins and minerals may be beneficial while your son heals.  

Hope this helps!