Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Celiac Lab Work. 2.5 yr old

Ngueyn1980
 Share

Recommended Posts

Ngueyn1980 Newbie
Ngueyn1980
Posted

My son is 2.5 years old. Symptoms are fluctuating diarrhea and constipation. Abdominal pain and bloating with vomiting. His labs game back as:

TISSUE TRANSGLUTAMINASE AB, IGA:

126.8 H

Reference Range: <15.0 U/mL 

GLIADIN (DEAMIDATED) AB (IGA):

<1.0

Reference Range: <15.0 U/mL 

GLIADIN (DEAMIDATED) AB (IGG):

6.3

Reference Range: <15.0 U/mL 

IMMUNOGLOBULIN A:

76

Reference Range: 20-99 mg/dL

ENDOMYSIAL ANTIBODY SCR (IGA) W/REFL TO TITER:

Positive

Reference Range: Negative

ENDOMYSIAL ANTIBODY TITER:

1:5

Reference Range: <1:5 titer

 

We have a GI appt on 12/2. I am hoping they will diagnose him with out an endoscopy. Poor little guy has been through so much already. 

 

 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


trents Grand Master
trents
Posted

Looks like he definitely has celiac disease from that high tTG-IGA and positive EMA. The tTG-IGA is considered the best all around antibody test for celiac disease, combining good sensitivity with good specificity. The EMA is less sensitive but is very specific for celiac disease. In some countries, i.e., the UK, if the tTG-IGA is 10x normal or greater they often will declare a celiac diagnosis without the endoscopy/biopsy. Your little guy fits that bill.

Scott Adams Grand Master
Scott Adams
Posted

I agree and this article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. 

 

 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,844
    • Most Online (within 30 mins)
      7,748
    ginsabol
    Newest Member
    ginsabol
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Gluten-Free Newbie

      By Scott Adams · Posted

      if you have already learned that Gluten is the cause of your symptoms, of course there is no need to add it back into your diet— your decision could save you a lot of needless suffering. One thing to consider is that if you do have celiac disease, your first- degree relatives may also need to get screened for it, because, like diabetes the disease is genetic, although many of its triggers seem to be environmental factors. You may want to consider getting a genetic test for celiac disease, so you can at least warn your relatives if it turns out that you do carry a celiac gene.
    • lookingforanswersone
      TTG IgA 0.30 U/ml: further tests?

      By lookingforanswersone · Posted

      Thanks everyone. I've decided to do a gluten challenge (4 slices of bread a day for 3 months) and then do a full gluten panel of all the tests that can be done, just to rule it in or out for sure. I think otherwise psychologically it will keep bothering me 
    • Suze046
      Gluten-Free Newbie

      By Suze046 · Posted

      Thanks Scott. Those articles are really interesting. I’m cutting out gluten for 6 weeks but honestly I’m not sure I even want to reintroduce it! I ate at a restaurant for the first time on Wednesday and then Thursday was really uncomfortable and had a few trips to the loo.. wonder if there was some cross contamination 🤷‍♀️ if that’s how my body reacts after not eating it for 3 weeks I’m not sure it’s worth reintroducing it and re testing for celiac! It might have been a coincidence I realise that I’m not going to feel better all of a sudden and my gut is probably still trying to heal. Thanks for your supportive message! 
    • RMJ
      TTG IgA 0.30 U/ml: further tests?

      By RMJ · Posted

      Reference range 0.00 to 10.00 means that within that range is normal, so not celiac. There are other antibodies that can be present in celiac disease and they don’t all have to be positive to have celiac.  I’m sure someone else will post a link to an article describing them! Plus, if you are IgA deficient the celiac IgA tests won’t be accurate.
    • cristiana
      Gluten Intolerance And Low White Blood Cell Counts?

      By cristiana · Posted

      Great to have another UK person on the forum!   Re: blood tests, it sounds as if you are being well monitored but if you have any further concerns about blood tests or anything else, do not hesitate to start a new thread. Cristiana  
×
×
  • Create New...