Vaccine For Cd

[debmidge]

Has anyone heard any more on this topic? I thought I read something recently that in 1999 some researcher somewhere (I think in UK) was working on a vaccine. Does anyone know the progress, or was I dreaming this up?

[flagbabyds]

I've never heard anything about that. I dunno if I just haven't heard of it. That would be really interesting but celiac disease is genitic and if you have the gene then you have it right? I don't know how a vaccine would kill the celiac disease gene.

[kejohe]

I have heard about the research being done for a gene suppressor... or at least I think that's what they are calling it. It's supposed to act just like Lactaid does for people who are lactose intolerant. It would supress the gene that makes a celiac a celiac so that they could consume gluten without the negative effects.

I haven't heard about wether or not it will be a daily medication or something that you would only take before you consumed gluten (like taking lactaid before eating cheesecake). And I haven't heard anything new in a while, so I kind of forgot about it until I read your post.

It would be cool to have something like that available, but like most medications, it takes years of tests to determine if there are any long term side effects, and I would be really timid to try it on my son, until he is old enough to decide for himself whether or not he wants to take the risks.

[flagbabyds]

I thought it would be more like a shot you give to little kids so they don't develop it later in life like the chicken pox vaccine and that is why i was confused. i know someone who has already found the gene and is now testing his pill(almost in pill form) on people in the Bay Area. his name is chaitan khloslav(sp?) and he lives in Palo Alto CAlifornia.

[debmidge]

I read about it on Celiac.com and the article was a little old. I was wondering if anyone had learned anything new about it.

[debmidge]

The original report can be found at celiac.com, go to Site Index, the find Diagnosis Testing & Treatment, then go to Austrialians Begin Work on vaccine. The report is foom 2002. It appears that a Dr. Robert Anderson of the Nuffield Dept of Medicine, University of Oxford, Australia was working on this.

[simone]

I don't know anything about a Celiac vaccine but there are many kinds of vaccines. I work at a company that makes gene therapeutics and from my understanding celiac disease is a lack of a proper gene that would help the body break down gluten, so the effect would have to be an enzyme/gene replacement rather than suppression.

Also, there is a connection with Celiac Disease and auto-immune disorders, meaning your body attacks it's own components. I am not sure how that directly ties into celiac disease as I am just now learning all of this. My guess is that a vaccine might have to somehow suppress the auto-immune response???

Anyone else have a clue? But don't take my word for it. I am just supposin'. I will look into that article and see what they indicate.

Simone

[debmidge]

I am anxious to know how far they are into the vaccine development and testing stage. I am afraid that with such little "press/media" coverage there is on celiac disease that Oxford could have a working vaccine without us knowing until it's been out there for years. Keep in mind that in the event that Oxford (Austrailia) has a vaccine, we woundn't have it here until that lab got FDA approval to sell it in the USA. That could add years onto it's distribution here. Celiacs would probably have to fly to Austrailia, or UK or possibly the islands in the Carribean which are owned by UK (Jamacia?) in order to get this vaccine and they'd have to pay cash $$ as insurance doesn't cover treatments outside of the USA yet.

[simone]

Yes, the FDA does take a long time to approve things. It is good in that long term effects can be observed but, coming from the other side, a company that wants to get products approved, there is a TON of paperwork.

Also want to confirm that from the vaccine article the process does indicate an immune system suppression with some fancy T-cell manipulation. Some day hopefully. . .

Keep your fingers crossed!

Simone

[kejohe]

Now that I think about it, Simone, your right about celiac being a lack of the correct gene to digest the gluten protiens so it must have been a response supressant that I read about. My nutrition and food science professor gave me the article about it after she found out my son had celiac, but it was almost 2 years ago that I heard of it, and nothing new since.

In any case, if it's trueand it really is being developed that would be great for

everyone.