Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Effectiveness Of Drugs

Caeli

Recommended Posts

Caeli Rookie
Caeli
Posted

The thought crossed my mind recently as to the effectiveness of drugs in the treatment of other medical problems in coeliacs.

The thought is that given coeliac disease atrophies the villi, that part of the small intestines that absorbs nutrients (in other words, the villi cannot work effectively in absorbing food etc), is it logical to conclude that drugs prescribed for various medical conditions would not be absorbed as well as they ought to be.

Has anybody any ideas, preferaly expert on this question? Has any research been done on this?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


debmidge Rising Star
debmidge
Posted

sure, makes sense that during the damage stage, the prescription or vitamin or whatever won't be absorbed (either not absorbed all the way or somewhat). After villi healing there should be more absorption.

I wonder what the absorption rate is in a healthy, non celiac small intestine --- do normal people absorb 100% or are there degrees of absorption in non celiac disease people?

jerseyangel Proficient
jerseyangel
Posted
The thought crossed my mind recently as to the effectiveness of drugs in the treatment of other medical problems in coeliacs.

The thought is that given coeliac disease atrophies the villi, that part of the small intestines that absorbs nutrients (in other words, the villi cannot work effectively in absorbing food etc), is it logical to conclude that drugs prescribed for various medical conditions would not be absorbed as well as they ought to be.

Has anybody any ideas, preferaly expert on this question? Has any research been done on this?

Hello Caeli! I have not seen you post here in a while. Hope your healing is going well. :)

Regarding drug effectivness, I have high blood pressure and take medication for it daily. As I have just passed the 1 year gluten-free mark, I am finding that my BP is lowering! My doctor has me monitoring it myself at home with a wrist monitor between appointments--so it's easy for me to track this. I think (and I plan to bring this up at my next appt) that possibly my intestine is healing now to the point where I am getting more of the drug's benefit. I'm not an expert, but that is my experience. Blessings!

marciab Enthusiast
marciab
Posted

I had to cut my Klonopin back from .5 mg to .125 mg because I was feeling completely drugged at the .5 mg dosage about 2 months ago. Approximately 6 months after going gluten free. I kepted lowering it from .5 to .125 gradually because I still felt drugged at the lesser doses too.

It was prescribed for nocturnal myoclonous and my current dosage appears to be enough to control it. I hope eventually to be able to stop it completely. It just takes time since it is a seizure med.

hope this helps ... marcia

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,558
    • Most Online (within 30 mins)
      7,748
    Wamedh Taj-Aldeen
    Newest Member
    Wamedh Taj-Aldeen
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Wamedh Taj-Aldeen
      Positive TTG antibody and negative EMA antibody

      By Wamedh Taj-Aldeen · Posted

      I recently reviewed a patient with a positive tissue transglutaminase (tTG) antibody but negative endomysial antibodies (EMA). The patient is asymptomatic, and duodenal biopsies—taken while on a normal gluten-containing diet—were reported as normal. Given the discordant serology and absence of histological changes, I understand that the probability of coeliac disease is low. However, I would appreciate your guidance on the following: Is routine follow-up required in such a case? What is the risk of progression to overt coeliac disease in the future? Would HLA DQ2/DQ8 typing be useful here to help guide long-term management or exclude the diagnosis confidently? I would be grateful for your thoughts.
    • trents
      Is "Shield" skincare products gluten-free?

      By trents · Posted

      @LynnM, when you say, "today, his numbers were high", what numbers do you refer to? Are you speaking of celiac antibody scores? Can you be more specific and can you post the test names, the numbers and the reference ranges for the tests? So, I am understanding you to say that topical exposure to gluten doesn't cause him GI reactions but ingestion of gluten does but at the same time you are attributing the "high numbers" to the topical exposure?
    • Ginger38
      Abnormal Labs, Should I Be Concerned?

      By Ginger38 · Posted

      So I recently had blood work and my hemoglobin, hematocrit, protein and alkaline phosphatase were all low. They have never been low in the past but since august of last year I have been on the in and off gluten rollercoaster as I mentioned in previous posts. Should I be concerned with these new findings? I am worried I have made myself really sick and done damage or something this past year 
    • LynnM
      Is "Shield" skincare products gluten-free?

      By LynnM · Posted

      Thank you Scott. My son doesn't have a reaction topically, only when ingested. Interestingly though, the doc told us the face cream getting gluten into his bloodstream doesn't do the damage akin to when gluten is ingested. He had no reaction when using the face cream, it only presented in blood-work. I'm hopeful from all the comments today and will wait for the GI doc to reply. If he is cleared to use it, I will encourage SHIELD to get a gluten-free certification 
    • Scott Adams
      Is "Shield" skincare products gluten-free?

      By Scott Adams · Posted

      It’s great that you’re taking the time to research products carefully for your son with celiac disease—especially since accidental gluten exposure through skincare can be a real concern for sensitive individuals. Based on the ingredient lists you’ve shared, none of the products appear to contain obvious sources of gluten like wheat, barley, or rye derivatives. Ingredients like glycerin and tocopherols (not listed here but often a concern) can sometimes be derived from wheat, but many manufacturers use plant-based or synthetic sources. SHIELD’s transparency and willingness to share their full ingredient list is a good sign, and their note about not intentionally adding gluten is reassuring. Still, because ingredient sourcing can vary and sensitivities differ from person to person, it’s wise that you’ve reached out to your GI specialist to be sure these products are safe for your son’s specific needs. In the meantime, if you do try any of the products, consider patch-testing them first and watching closely for any signs of skin irritation or reactions. PS - Most people with celiac disease won't react to skin products that may contain gluten, but I still recommend finding gluten-free products.
×
×
  • Create New...