Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Endo Results - Duodenum With Focal Gastric Metaplasia

ravenwoodglass

Recommended Posts

ravenwoodglass Mentor
ravenwoodglass
Posted

I had an endo a couple of weeks ago. After 5 years gluten-free there was no evidence of celiac so I guess I have healed nicely. However the biopsy report stated that they found Focal Gastric Metaplasia in the specimens. My doctor thinks they messed up at the lab and made a mistake and is comfortable waiting a year or so and then redoing the biopsy. He said visually everything looked fine. To my understanding the finding suggest either cancer or a precancerous condition but I don't want to jump to conclusions.

Would you want a second opinion? Do you think they can reuse the same slides or do I have to go through everything again. It was a horrible experience as the doc was in a hurry and started everything before the meds had a chance to take effect. Not something I want to repeat in a hurry unless needed.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Jestgar Rising Star
Jestgar
Posted

I would totally get a second opinion or I'd be a basket case for a year.

Have the slides read by a different person/lab/technician, whatever is appropriate, and if the same results are found you can consider another biopsy (by a different doctor would be my suggestion).

Jestgar Rising Star
Jestgar
Posted

I just found someone's powerpoint presentation about this

FGM

It looks as if it's associated with H.pylori, focal has a low risk of progressing to anything more serious, and treating the H.pylori may have some benefit.

ravenwoodglass Mentor
ravenwoodglass
Posted
  • Author

Thanks for the reply and the link. Do you know how they test for H pylori, would it be likely in someone who only rarely has any signs of heartburn or reflux? I am assuming it would be prudent to ask for a test for it. The treatment is antibiotics, correct?

Jestgar Rising Star
Jestgar
Posted

I think it's a blood test to look for antibodies.

The treatment is (or was a couple years ago) antibiotics along with PPIs to decrease the acidity of your stomach and make the bacteria more susceptible to the antibiotics.

I read somewhere that H.pylori is really prevalent, but not everyone has symptoms from it.

Still, it's just a blood test...

ravenwoodglass Mentor
ravenwoodglass
Posted
  • Author

Good, I am going to call my GI Monday to find out if he tested for it. I should think he would have suggested testing but but then again this guy doesn't even know celiac can cause any symptoms other than GI. You set my mind at ease a bit. I guess I can stop labeling my treasures as to who gets what for a bit longer. :unsure: I don't know what I would do if I did have cancer, I would be afraid they would poison me with treatments or hospital food.

Jestgar Rising Star
Jestgar
Posted
I guess I can stop labeling my treasures as to who gets what for a bit longer. :unsure:

Put my name on your collection of gluten-free recipes! ;)

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mamabear Explorer
mamabear
Posted
Thanks for the reply and the link. Do you know how they test for H pylori, would it be likely in someone who only rarely has any signs of heartburn or reflux? I am assuming it would be prudent to ask for a test for it. The treatment is antibiotics, correct?

Ravenwoodglass,

Ask for a copy of the pathology report. Most EGD biopsy specimens are stained for H Pylori as a routine. The report should state on there somewhere if it was done. Otherwise there are 2 available blood based tests..one is from a venipuncture and the other is a rapid fingerstick method similar to a strep test. Both test for antibodies to the bacteria.

ravenwoodglass Mentor
ravenwoodglass
Posted
  • Author
Ravenwoodglass,

Ask for a copy of the pathology report. Most EGD biopsy specimens are stained for H Pylori as a routine. The report should state on there somewhere if it was done. Otherwise there are 2 available blood based tests..one is from a venipuncture and the other is a rapid fingerstick method similar to a strep test. Both test for antibodies to the bacteria.

Thanks so much for the reply. I did get the actual report along with copies of all my labs. It does not mention any yes or no as far as the HP issue.

The microscopic finding were: 'partial gastric metaplasia with foveolar epithelium. Brunner's glands present. The segment with gastric metaplasia some of the glands show increased nuclear cytoplasmic ration and hyperchromasia. Also patchy inflammation.'

I will contact Monday and ask directly. Perhaps it is there and I missed it. Or he may not have tested for it because I haven't had any stomach pain. I have wondered if the ?discomfort? that I have been interpreting as hunger may actually be related to an ulcer. I had not felt hungry in years before my diagnosis. I have at times gone days without eating and lived off very little food for a long time. I think my brain learned how to just ignore hunger. Pain is perceived differently by different folks and I endured so much for so long that a couple occasional twinges seem pretty insignificant.

I wish the doctor and I could have spent more time discussing the findings but most of the visit was spent with me telling him the drugs didn't work and him telling me they did. He was supposed to not do the endo if there were problems with the colonoscopy but I think he thought I was out of it and wouldn't remember so he just went ahead anyway. I had nightmares for almost 3 weeks and some bruising on my jaw, arms and strained back and leg muscles. I, thank goodness, do not remember anything after they made me swallow the scope, at least not consiously.

They are doing a CT on Tuesday with water soluable (and I pray gluten-free) solution and no IV contrast so hopefully the 'tortuous' colon and the 'lump' that I have had growing for a while will no longer be a mystery after that. That was my main concern to begin with and the endo was just done IMHO to satisfy the doctors very long desire to do one on me. He brushed off IBS for years as I got sicker and sicker, insisting it was all in my head. I don't want him to just consider the biopsy report a mistake and ignore it.

mamabear Explorer
mamabear
Posted

Ravenwoodglass,

I read the link provided by Jestgar and it looks like annual EGD is the best way to monitor the metaplasia. Getting the CT scan will add extra information...sometimes MRI's of the abdomen are also done . If H pylori is involved, looks like treatment lessens the chance of malignancy.

Let us know what your follow up tests show.

  • 10 years later...
Maddiecl Explorer
Maddiecl
Posted

Hello Ravenwoodglass,

I know this is a verrry old thread but I recently got some biopsy results that also said I had Gastric Metaplasia.  Can you tell me what you are doing to monitor this condition, and what you know about it?  My doctor just told me not to worry about it, but the fact that it is considered a pre-cancerous condition is freaking me out. 

I really appreciate it.

Thanks!

cyclinglady Grand Master
cyclinglady
Posted

@Maddiecl — Be patient!  Ravenwoodglass is still very active on the forum.  I am sure she will reply soon.  ?

Try not to worry.  I know, easier said than done!  

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,019
    • Most Online (within 30 mins)
      7,748
    Wilson1984
    Newest Member
    Wilson1984
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • sleuth
      Nicotine Gum For Gluten Symptoms.. Am I Crazy?

      By sleuth · Posted

      He is not just a psychiatrist.  He is also a neuroscientist.  And yes, I have already read those studies.   I agree with benfotiamine.  This is short term while glutened/inflammation occurs.  As I had already mentioned, these symptoms no longer exist when this phase passes.  And yes, I know that celiac is a disease of malnutrition.  We are working with a naturopath.
    • knitty kitty
      Nicotine Gum For Gluten Symptoms.. Am I Crazy?

      By knitty kitty · Posted

      Please do more research before you settle on nicotine. Dr. Paul New house is a psychiatrist.  His latest study involves the effect of nicotine patches on Late Life Depression which has reached no long term conclusions about the benefits.   Effects of open-label transdermal nicotine antidepressant augmentation on affective symptoms and executive function in late-life depression https://pubmed.ncbi.nlm.nih.gov/39009312/   I'm approaching the subject from the Microbiologist's point of view which shows nicotine blocks Thiamine B1 uptake and usage:   Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells https://pubmed.ncbi.nlm.nih.gov/26633299/   While supplementation with thiamine in the form Benfotiamine can protect from damage done by  nicotine: Benfotiamine attenuates nicotine and uric acid-induced vascular endothelial dysfunction in the rat https://pubmed.ncbi.nlm.nih.gov/18951979/   I suggest you study the beneficial effects of Thiamine (Benfotiamine and TTFD) on the body and mental health done by Dr. Derrick Lonsdale and Dr. Chandler Marrs.  Dr. Lonsdale had studied thiamine over fifty years.   Hiding in Plain Sight: Modern Thiamine Deficiency https://pmc.ncbi.nlm.nih.gov/articles/PMC8533683/ I suggest you read their book Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition.     Celiac Disease is a disease of malabsorption causing malnutrition.  Thiamine and benfotiamine: Focus on their therapeutic potential https://pmc.ncbi.nlm.nih.gov/articles/PMC10682628/
    • sleuth
      Nicotine Gum For Gluten Symptoms.. Am I Crazy?

      By sleuth · Posted

      Thanks for your response.  Everything you mentioned he is and has been doing.  Tobacco is not the same as nicotine.  Nicotine, in the form of a patch, does not cause gastrointestinal irritation.  Smoking does. He is not smoking.  Please do your research before stating false information. Dr. Paul Newhouse has been doing research on nicotine the last 40 years at Vanderbilt University Medical Center.  
    • Jmartes71
      Fighting for a name

      By Jmartes71 · Posted

      Im so frustrated and still getting the run around trying to reprove my celiac disease which my past primary ignored for 25 years.I understand that theres a ray of medical that doctors are limited too but not listening and telling the patient ( me) that im not as sensitive as I think and NOT celiac!Correction Mr white coat its not what I think but for cause and affect and past test that are not sticking in my medical records.I get sick violently with foods consumed, not eating the foods will show Im fabulous. After many blood draws and going through doctors I have the HLA- DQ2 positive which I read in a study that Iran conducted that the severity in celiac is in that gene.Im glutenfree and dealing with related issues which core issue of celiac isn't addressed. My skin, right eye, left leg diagestive issues affected. I have high blood pressure because im in pain.Im waisting my time on trying to reprove that Im celiac which is not a disease I want, but unfortunately have.It  has taken over my life personally and professionally. How do I stop getting medically gaslight and get the help needed to bounce back if I ever do bounce back to normal? I thought I was in good care with " celiac specialist " but in her eyes Im good.Im NOT.Sibo positive, IBS, Chronic Fatigue just to name a few and its all related to what I like to call a ghost disease ( celiac) since doctors don't seem to take it seriously. 
    • trents
      Celiac getting dentures

      By trents · Posted

      @Martha Mitchell, your reaction to the lens implant with gluten sounds like it could be an allergic reaction rather than a celiac reaction. It is possible for a celiac to be also allergic to gluten as it is a protein component in wheat, barley and rye.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.