Lab Results - Need Interpretation

[tulsagal]

I finally received copies of my labs and even after talking with my doctor, I'm confused on these results:

Results from Regional Medical Laboratory:

Tissuetrans IgA: 4 ( 0-19)

Gliadin IGG AB: 3 (0-19)

Gliadin IGA AB: 7 (0-19)

Total IGA: 370 (71-263)

Can someone help me interpret these?

Teresa

[VydorScope]

I finally received copies of my labs and even after talking with my doctor, I'm confused on these results:

Results from Regional Medical Laboratory:

Tissuetrans IgA: 4 ( 0-19)

Gliadin IGG AB: 3 (0-19)

Gliadin IGA AB: 7 (0-19)

Total IGA: 370 (71-263)

Can someone help me interpret these?

Teresa

What did your doc say?

Your Total IGA is above range, but the rest are normal. Are you on a gluten-free diet? if so how long?

[chrissy]

your tests are negative for celiac. your total IgA is higher than normal---which doesn't necessarily mean anything.

[tulsagal]

I am not on a gluten-free diet, although I do try and eat low carb most of the time and I do eat the occasional whole wheat bread and Kashi cereal and bars, etc.

My doctor, who happens to be Celiac herself, took more blood and sent it off to Stanford (I think) for more testing. I told her I wanted to know more before having a biopsy done - if at all. She also is doing food allergy testing.

I realize that a negative tTG means Celiac is not likely and a negative Anti-gliadin IGA means that I'm not having an immune response to gluten, but I was puzzled by the above-range Total IGA. Would a wheat or other food allergy cause that to be elevated?

Teresa

[Nancym]

A high IGA is associated with gluten sensitivity according to Dr. Lewey thefooddoc.com. You might still have celiac disease though, it would take a biopsy to know for sure. There's also a lot of people with brain related gluten sensitivity that have IGA and nothing else.

Either way, you should still try the diet, you might be surprised.

[nora-n]

My daughter got an official diagnosis in spite of both negative blood tests and biopsies.

She got so much better off gluten, and even her graves antibodies disappeared.

Before, she had this pain everyday and had to run to the bathroom all day , and many of the other possible symptoms.

nora

[chrissy]

A high IGA is associated with gluten sensitivity according to Dr. Lewey thefooddoc.com. You might still have celiac disease though, it would take a biopsy to know for sure. There's also a lot of people with brain related gluten sensitivity that have IGA and nothing else.

????? everyone has IgA---unless they are IgA deficient.

[kerrih]

The TTG or tissuetransglutaminase result is most sensitive for diagnosing celiac disease. I had all normal results except for the TTG level. Yours shows 4 which is quite normal. Mine showed a number of 52. I had a negative biopsy, but most Dr.s will still consider me celiac. I have been on the gluten free diet for over a year and feeling much better. I am 34 yrs old and have had problems since Jr. High school. Hope this helps.

Kerri

[aikiducky]

It's quite common for blood tests to be negative if the disease hasn't progressed very far yet. It's even possible to have negative blood tests and a positive biopsy. It's good that your doc wants to investigate this further.

Pauliina