Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Possible Enzyme Treatment?


FatAsian860

Recommended Posts

FatAsian860 Newbie

I've been reading this forum for a while now, and I want to thank everyone for their great advice. I never registered or posted anything because I didn't have anything important to contribute, but I think I've come across something noteworthy. The latest issue of Gut describes a new enzyme called prolyl endoprotease that breaks down gluten before it reaches the small intestine. They only tested it in a model of the human GI tract, but I was really excited when I read that it was very effective in breaking down gluten from bread and a fast food meal. You can read the abstract at Open Original Shared Link. I also wrote about it on my blog, which I won't link to because I don't want to violate the board rules (but it's in my profile, if you're interested). If this actually works on humans, it would be like taking Lactaid for lactose intolerance. But that's a big "if", since clinical trials haven't been done yet. They briefly described how the T-cell response was reduced when an enzyme-treated sample was incubated with T-cells, but this probably isn't the best representation of the immune system. Still, this treatment seems to have a lot of potential and sounds better than the anti-inflammatory approach that other treatments are geared towards.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,227
    • Most Online (within 30 mins)
      7,748

    tillieh7
    Newest Member
    tillieh7
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):




  • Who's Online (See full list)

    • There are no registered users currently online

  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Wheatwacked
      Other symptoms that Celiac Disease can cause but resemble other diseases so the cause may be misdiagnosed. What Are the Symptoms of Celiac Disease?  
    • trents
    • sillyac58
      Thanks Scott. They are gluten-free but cross contaminated. 
    • cristiana
      Hi there @MCAyr I have a small umbilical hernia which came about during my second pregnancy.   I can just about see it, and feel it, when I stand or sit, but it is far less noticeable when I lie down.  I always know when I am putting on weight because I can get pain and burning near the site, funnily enough not on the hernia itself but either side!  I would imagine bloating could cause the same effect as weight gain. In my case I don't think it is my bowel protruding but a bit of fat  - sorry,  I realise this isn't painting a very pretty picture.  But in truth it is scarcely noticeable.  It has never really got bigger in size. I was rather hoping that it could be operated on but here in the UK they don't seem to operate on every hernia anymore.  My GP isn't remotely worried about it. In a way, I should be thankful - it is like an early warning system that I need to go on a diet! Cristiana
    • Scott Adams
      The hernia description would likely be unrelated to celiac disease, but you'd need to get it checked out by your doctor to be sure it's a hernia.
×
×
  • Create New...