Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Science Project


home-based-mom

Recommended Posts

home-based-mom Contributor

I am posting this here and in the "Parents" section and asking the moderators to make it a "sticky" for at least a while for maximum exposure. :rolleyes:

I am still kinds new here but have seen anecdotal reports that there are at least 3 things that might - just might - disable the gluten protein.

Those three things are:

  1. Whatever it is that makes sourdough bread sourdough
  2. Vinegar
  3. Rubbing Alcohol

So, high school and college students, design an experiment to see if any of them really do disable the gluten protein. Check for all sorts of variables such as temperature, concentration, salinity, ph, exposure time, etc. and all that stuff.

Work with your science teacher or someone from a local university so you get really good results.

Why, you might well ask? While none of this would enable anyone to start eating gluten again, think of how it could eliminate cross-contamination! Think washing utensils and counter tops at home - especially for those who have no choice but to share homes with those who eat gluten. Think commercial processors between batches. Think of something I haven't thought of!

Not only could this be an enormous benefit, but it would raise awareness at the same time!

Go For It!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Cinnamon Apprentice

This sounds very interesting. I've read other posts about trying vinegar or rubbing alcohol for cleaning gluten-contaminated surfaces. But yet I don't think it could be possible that vinegar or alcohol could disable the gluten molecule because if it could, then people could use malt vinegar and drink beer. Unless there is some variable that would enable it to do so, I don't really understand the chemistry behind it.

Do you have any more information as to how the vinegar or alcohol would work? What's the theory behind it? I tried to search the internet for more info, but all I could find were articles or advertisments for gluten-free things. I'd love to think up some experiments, even though I'm no kid!

Cinnamon Apprentice

Actually, I think the only real way to break down the gluten molecule would be with an enzyme similar to the one normal people have. Acidity won't do it or the acidic conditions in our stomachs would take care of it. Temperature won't do it or it would be destroyed by baking.

One day I think people will come up with a way to duplicate the enymatic action that normal people have, and that will be the way to go. Hopefully soon!

Ursa Major Collaborator

I just want to say that we can't make 'stickies' that stay up at the top. We do pin every new post, though (if it doesn't violate board rules, that is), putting it temporarily at the top, until another post gets pinned, or gets a reply.

It sounds like an interesting experiment. But how would anybody know what works and what doesn't, without purposely taking the risk of getting glutened? Unless you have a gluten measuring kit, of course, but not many people do.

home-based-mom Contributor
I just want to say that we can't make 'stickies' that stay up at the top. We do pin every new post, though (if it doesn't violate board rules, that is), putting it temporarily at the top, until another post gets pinned, or gets a reply.

It sounds like an interesting experiment. But how would anybody know what works and what doesn't, without purposely taking the risk of getting glutened? Unless you have a gluten measuring kit, of course, but not many people do.

It has been far too long since I took chemistry, but I imagine you could isolate the protein, put it into a flask or a petrie dish or some other chemistry lab container and just subject it to controlled versions of all the above mentioned abuse. Then see what happens!

This definitely falls into the "don't try this at home" category and I hope I didn't imply that someone should volunteer to be a guinea pig!

It would need to be done under carefully monitored and controlled conditions such as in a laboratory environment. It would have to be done in such a way that it could be written up in a scientific journal and pass scrutiny.

lizard00 Enthusiast

Just to add to your list of possibilities, I've read that papain, an enzyme in papaya has a property that renders gluten harmless....

Although I wouldn't dare try it. Another experiment for the lab!

Liz

Takala Enthusiast

Thou shalt not eat the results as rubbing alcohol is deadly poisonous.

Just wanted to throw that in there, one never knows what sort of crazy things kids will attempt to do.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



home-based-mom Contributor
Thou shalt not eat the results as rubbing alcohol is deadly poisonous.

Just wanted to throw that in there, one never knows what sort of crazy things kids will attempt to do.

Sigh. :( I was hoping people would know that!

Maybe I should point out that the purpose of this experiment is not to make make gluten safe to eat, it is to avoid - or at least greatly lessen - the possibility of getting cc'd from processing equipment, pots and pans, wooden spoons, counter tops colanders, stuff like that.

If it could be shown that some combination of one of these substances at a particular temperature or concentration for a certain length of time (or whatever) breaks up the gluten protein, then that method could become standard for cleaning items that have become contaminated with gluten.

Or the experimenter could try every combination imaginable and show that nothing works better than soap and water does to just wash it away.

The whole point is to investigate and find out.

Inquiring minds want to know! :rolleyes:

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - GlorietaKaro replied to GlorietaKaro's topic in Super Sensitive People
      3

      Am I nuts?

    2. - trents replied to GlorietaKaro's topic in Super Sensitive People
      3

      Am I nuts?

    3. - lalan45 replied to xxnonamexx's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      29

      My journey is it gluten or fiber?

    4. - Russ H posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Anti-endomysial Antibody (EMA) Testing

    5. - Scott Adams replied to JoJo0611's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      1

      Just diagnosed today

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      132,806
    • Most Online (within 30 mins)
      7,748

    IleneG
    Newest Member
    IleneG
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • GlorietaKaro
      Thanks to both of you for your responses!  Sadly, even after several years of very strict gluten avoidance, I remember the symptoms well enough that I am too frightened to risk a gluten challenge— heartbeat and breathing problems are scary— Scott, thank you for the specific information— I will call around in the new year to see if I can find anyone. In the meantime, I will carry on has I have been— it’s working! Thanks also for the validation— sometimes I just feel crushed by disbelief. Not enough to make me eat gluten though—
    • trents
      Welcome to the celiac.com community, @GlorietaKaro! As Scott indicated, without formal testing for celiac disease, which would require you to have been consuming generous amounts of gluten daily for weeks, it would be not be possible to distinguish whether you have celiac disease or NCGS (Non Celiac Gluten Sensitivity). Their symptoms overlap. The difference being that celiac disease is an autoimmune disorder that damages the lining of the small bowel. We actually no more about celiac disease than we do about NCGS, the mechanism of the latter being more difficult to classify. There are specific antibody tests for celiac disease diagnosis and there is also the endoscopy/biopsy of the small bowel lining. Currently, there are no tests to diagnose NCGS. Celiac disease must first ruled out. Researchers are working on developing testing methods to diagnose celiac disease that do not require a "gluten challenge" which is just out of the question for so many because it poses serious, even life-threatening, health risks. But we aren't there yet.
    • lalan45
      That’s really frustrating, I’m sorry you went through that. High fiber can definitely cause sudden stomach issues, especially if your body isn’t used to it yet, but accidental gluten exposure can feel similar. Keeping a simple food/symptom journal and introducing new foods one at a time can really help you spot patterns. You’re already doing the right things with cleaning and separating baking—also watch shared toasters, cutting boards, and labels like “may contain.”
    • Russ H
      I thought this might be of interest regarding anti-EMA testing. Some labs use donated umbilical cord instead of monkey oesophagus. Some labs just provide a +ve/-ve test result but others provide a grade by testing progressively diluted blood sample. https://www.aesku.com/index.php/ifu-download/1367-ema-instruction-manual-en-1/file Fluorescence-labelled anti-tTG2 autoantibodies bind to endomysium (the thin layer around muscle fibres) forming a characteristic honeycomb pattern under the microscope - this is highly specific to coeliac disease. The binding site is extracellular tTG2 bound to fibronectin and collagen. Human or monkey derived endomysium is necessary because tTG2 from other mammals does not provide the right binding epitope. https://www.mdpi.com/1422-0067/26/3/1012
    • Scott Adams
      First, please know that receiving two diagnoses at once, especially one you've never heard of, is undoubtedly overwhelming. You are not alone in this. Your understanding is correct: both celiac disease and Mesenteric Panniculitis (MP) are considered to have autoimmune components. While having both is not extremely common, they can co-occur, as chronic inflammation from one autoimmune condition can sometimes be linked to or trigger other inflammatory responses in the body. MP, which involves inflammation of the fat tissue in the mesentery (the membrane that holds your intestines in place), is often discovered incidentally on scans, exactly as in your case. The fact that your medical team is already planning follow-up with a DEXA scan (to check bone density, common after a celiac diagnosis) and a repeat CT is a very proactive and prudent approach to monitoring your health. Many find that adhering strictly to the gluten-free diet for celiac disease helps manage overall inflammation, which may positively impact MP over time. It's completely normal to feel uncertain right now. Your next steps are to take this one day at a time, focus on the gluten-free diet as your primary treatment for celiac, and use your upcoming appointments to ask all your questions about MP and what the monitoring plan entails. This dual diagnosis is a lot to process, but it is also the starting point for a managed path forward to better health. This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.