Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Enterolab

OBXMom

Recommended Posts

OBXMom Explorer
OBXMom
Posted

Can anyone tell me if it is worse to have both elevated Fecal Antigliadin & Fecal Antitissue Transglutaminase, rather than just the first? We got our Enterolab results today, and I'm comparing my daughter and myself.

Fecal Antigliadin IgA - Hers - 182, Mine - 16

Fecal Antitissue Transglutaminase IgA - Hers 103, mine -normal range (8)

I know when you are positive, you are positive, but don't her higher numbers, plus the double positive, indicate her system is having more problems right now?

Also, I am embarassed to admit I need help with the genetic info. I have read a number of posts, but I can't figure out which part of the numbers you turn into the DQ1 & 2 and so on.

Hers: HLA - DQB1, Allele 1 0201

HLA-DQB1, Allele 2, 202

HLA-DQ 2,2 (Subtype 2,2)

Mine HLA-DQB1, Allele 1, 202

HLA-DQB1, Allele 2, 0603

HLA-DQ 2,1 (Subtype 2,6)

Thank you for any help. All evening I've been trying to figure this out, and I feel like the little engine that could (I think I can, I think I can . . .)

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


holiday16 Enthusiast
holiday16
Posted

Did you happen to figure out the gene part yet? My son had the same DQ2 (0202) and it took me a while to figure out how it was different from the DQ2 (0201). Wikipedia helped alot, but wow is it confusing!!!

fedora Enthusiast
fedora
Posted

hi,

Your daughter has the celiac gene DQ2. This is also known as DQ2.5. It is HLA - DQB1, Allele 1 0201

It can cause full blown celiac. She must have got this from her dad.

The other gene is DQ2.2. It is HLA-DQB1, Allele 2, 202. I has half of the celiac gene DQ2. It is definately a gluten intolerant gene and in some instances it can cause full blown celiac. She got this gene from you.

You have the same DQ2.2 gene. so you have half the celiac gene which sometimes(rarely) manifests as full blown celiac.

DQ6 your other gene is seen in gluten intolerant patients.

The difference in the antibody levels is your daughter has antibodies against her own body tissue(the ttg antibodies). This is worse. Yours may have gotten higher over time.

You both are reacting to gluten. Did you get the malabsorption test done too?

Hope she is feeling better.

neesee Apprentice
neesee
Posted

Here's a little extra info. Open Original Shared Link

OBXMom Explorer
OBXMom
Posted
  • Author

Thank you all for your help. I hadn't figured it out yet, and finally called Enterolab today, and was promised a callback in 48 hours, which didn't thrill me. But now I really don't need them, thanks to you. But it is just so complicated, isn't it?

Fedora, we did do the malabsorption test, and we were both o.k. there. However, my daughter was also positive for anti-casein (cow's mlk) at 108 units, with <10 being normal. I didn't realize that she had antibodies against her own tissue, thank you for explaining that, although I have to admit it sounds scary. I'm wondering if she might have a leaky gut.

Thanks again, now I can go back and read all the stuff with the genes abbreviated and know which we are.

fedora Enthusiast
fedora
Posted

OBXMom

Thank is great that your malabsorption was fine. Mine was too. I was gluten and casein intolerant. I also had ttg antibodies against my own tissue. This is how the auto immune damage is done. Has their dad been checked? They had to have gotten the celiac gene from him.

I am awaiting my DD enterolab results. I am officially impatient today. It has been over 2 weeks.

nora-n Rookie
nora-n
Posted

Here is the wiki:

Open Original Shared Link

enterolab reporting which kind of DQ2 beta chain they found, is a bit new, i did not read postings of reports like taht last year.

The latest news are also that some other labs test for the alpha chains, to find the half genes, which also predispose for celiac. Enterolab does not test for them, but Kimball genetics does, but they do not test for anything but DQ2 or 8, so some peole might end up to have to order two sets of genetic tests, one from enteroplab and one from Kimball genetics...

Open Original Shared Link

Open Original Shared Link

nora

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


OBXMom Explorer
OBXMom
Posted
  • Author
OBXMom

Thank is great that your malabsorption was fine. Mine was too. I was gluten and casein intolerant. I also had ttg antibodies against my own tissue. This is how the auto immune damage is done. Has their dad been checked? They had to have gotten the celiac gene from him.

I am awaiting my DD enterolab results. I am officially impatient today. It has been over 2 weeks.

Hi Fedora,

My husband says he will just do a gluten free trial with us, but I wonder if he would be more convinced if we tested him, too. His only symptoms are bad allergies and skin rashes (not DH.)

I have to tell you, I checked Enterolab constantly to make sure the results weren't posted while we waited, and the day that I thought was 3 weeks I called. They said they were exactly at 3 weeks (starting count the day after they received the kit) and that it would come at the end of the next day. They meant it - I got them at about 5:00 pm. Maybe you will be luckier than we were, but if I were you I wouldn't expect it early. . .

OBXMom Explorer
OBXMom
Posted
  • Author

Thank you, Nora, I will pore over these. I wish I could absorb all of this more quickly. I really appreciate the help.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. trents
      - trents replied to mamaof7's topic in Parents, Friends and Loved Ones of Celiacs
      7

      Help understand results

      Actually, it would be more correct to say that the genetic potential to develop celiac disease is passed down from parents to children. About 40% of the general population has the genetic potential to develop celiac disease but only about 1% of the general population actually do. But it is also true that the offspring of those who do have active celiac disease...
    2. Jordan Carlson
      - Jordan Carlson posted a topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      0

      Fruits & Veggies

      Hello everyone! Been a while since I posted. The past few moths have been the best by for recovery for myself. I have been the least bloated I have ever been, my constant throat clearing is almost gone, I have stopped almost all medication I was prevously taking (was taking vyvanse for adhd, pristiq for anxiety,fomotadine/blexten for histamine...
    3. wellthatsfun
      - wellthatsfun posted a topic in Gluten-Free Recipes & Cooking Tips
      0

      heaps of hope!

      i know i've been rather cynical and sad about being fully diagnosed in june 2025, but my boyfriend has been consistently showing me the wonderful world that is gluten free cooking and baking. in the past couple of days he's made me a gluten free rice paper-wrapped spanakopita "pastry", plus a wonderful mac and cheese bechamel-ish sauce with gluten free...
    4. Tanisha L
      - Tanisha L commented on Scott Adams's article in Kids and Celiac Disease
      1

      New Study Reveals Age and Racial Gaps in Pediatric Celiac Testing

      I am a 47yr old African American woman and did not receive a celiac diagnosis until 2yrs ago. This late diagnosis proved to be challenging to me because it was a culture shock to me. I have a cultural background of Hispanic and West Indian and a lot of our foods are heavy flour based. I was told be my dietician that unfortunately African American families...
    5. knitty kitty
      - knitty kitty replied to mamaof7's topic in Parents, Friends and Loved Ones of Celiacs
      7

      Help understand results

      That test is saying that your daughter is not making normal amounts of any IGA antibodies. She's not making normal amounts of antibodies against gliadin, not against bacteria, not against viruses. She is deficient in total IGA, so the test for antigliadin antibodies is not valid. The test was a failure. The test only works if all different kinds of antibodies...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      132,997
    • Most Online (within 30 mins)
      7,748
    IwannabHealthy
    Newest Member
    IwannabHealthy
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • trents
      Help understand results

      By trents · Posted

      Actually, it would be more correct to say that the genetic potential to develop celiac disease is passed down from parents to children. About 40% of the general population has the genetic potential to develop celiac disease but only about 1% of the general population actually do. But it is also true that the offspring of those who do have active celiac disease are at a considerably higher risk of developing active celiac disease than those of parents who have the genes but don't develop the disease. Some recent, larger studies put the risk at near 50% for the first degree relatives of those who have active celiac disease.
    • Jordan Carlson
      Fruits & Veggies

      By Jordan Carlson · Posted

      Hello everyone! Been a while since I posted. The past few moths have been the best by for recovery for myself. I have been the least bloated I have ever been, my constant throat clearing is almost gone, I have stopped almost all medication I was prevously taking (was taking vyvanse for adhd, pristiq for anxiety,fomotadine/blexten for histamine blockers and singulair). Only thing I take now is Tecta. I also no longer get any rashes after eating. Things are going very well. Most success came actually once I upped my B12 daily dose to 5,000 mcg. I do have one thing I am un able to figure out and want to see if anyone else has this issue or has experience working around it. Ever since I was born I have always had a issue getting fruits and veggies down. No matter how hard I tried, it would always result in gagging or throwing up. Always just thought I was a picky eater. Now that my stomach and system has healed enough that I can feel when something is off almost istantly, I notice that after eating most fruits (sometimes I am ok with bananas) and veggies, my stomach instantly starts burning and my heart starts to pound and I get really anxious as if my body doesnt know what to do with what just enetered it. So I am thinking now that this is what probably was going on when I was born and my body started rejecting it before which caused this weird sensory issue with it causing the gagging. Hoping someone has some exprience with this as well because I would love to be able to enjoy a nice fruit smoothie once in a while haha. Thanks everyone!
    • wellthatsfun
      heaps of hope!

      By wellthatsfun · Posted

      i know i've been rather cynical and sad about being fully diagnosed in june 2025, but my boyfriend has been consistently showing me the wonderful world that is gluten free cooking and baking. in the past couple of days he's made me a gluten free rice paper-wrapped spanakopita "pastry", plus a wonderful mac and cheese bechamel-ish sauce with gluten free pasta (san remo brand if you're in australia/if you can get your hands on it wherever you are).  those meals are notably gluten free, but mainly he's been making me easy gluten free meals - chili mince with white rice and sour cream, chicken soup with homemade stock from the chicken remains, and roast chickens with rice flour gravy and roast veggies. i'm a bit too thankful and grateful lol. how lucky could i possibly be? and, of course, for those who don't have someone to cook for them, it's quite easy to learn to cook for yourself. i've been making a lot of meals for us too. honestly, cooking is pretty darn fun! knowing basic knife skills and sanitary practices are all you really need. experimenting with spices will help you get on track to creating some really flavourful and yummy dishes. coeliac is a pain, but you can use it to your advantage. healthier eating and having fun in the kitchen are major upsides. much luck to all of you! let's be healthy!
    • knitty kitty
      Help understand results

      By knitty kitty · Posted

      That test is saying that your daughter is not making normal amounts of any IGA antibodies.  She's not making normal amounts of antibodies against gliadin, not against bacteria, not against viruses.  She is deficient in total IGA, so the test for antigliadin antibodies is not valid.  The test was a failure.  The test only works if all different kinds of antibodies were being made.  Your daughter is not making all different kinds of antibodies, so the test results are moot.  Your daughter should have the DGP IgG and TTG IgG tests done.   The tests should be performed while she is still consuming gluten.  Stopping and restarting a gluten containing diet can make her more sick, just like you refuse to eat gluten for testing.  Call the doctor's office, request both the IGG tests. Request to be put on the cancellation list for an appointment sooner.  Ask for genetic testing.   Celiac disease is passed on from parents to children.  You and all seven children should be tested for genes for Celiac disease.  Your parents, your siblings and their children should be tested as well.  Eating gluten is not required for genetic testing because your genes don't change.  Genetic testing is not a diagnosis of Celiac disease.  Just having the genes means there is the potential of developing Celiac disease if the Celiac genes are activated.  Genetic testing helps us decide if the Celiac genes are activated when coupled with physical symptoms, antibody testing, and biopsy examination. It's frustrating when doctors get it wrong and we suffer for it.  Hang in there.  You're a good mom for pursuing this!  
    • knitty kitty
      Insomnia help

      By knitty kitty · Posted

      @hjayne19, So glad you found the information helpful.  I know how difficult my struggle with anxiety has been.  I've been finding things that helped me and sharing that with others makes my journey worthwhile. I like Life Extension Bioactive Complete B Complex.  It contains the easily activated forms of B vitamins needed by people with the MTHFR genetic variation often found with Celiac disease.   Avoid B Complex vitamins if they contain Thiamine Mononitrate if possible.  (Read the ingredients listing.)  Thiamine Mononitrate is the "shelf-stable" form of B 1 that the body can't utilize.  B vitamins breakdown when exposed to heat and light, and over time.  So "shelf-stable" forms won't breakdown sitting on a shelf in a bright store waiting to be bought.  (It's also very cheap.)  Thiamine Mononitrate is so shelf-stable that the body only absorbs about thirty percent of it, and less than that is utilized.  It takes thiamine already in the body to turn Thiamine Mononitrate into an active form.   I take MegaBenfotiamine by Life Extension.  Benfotiamine has been shown to promote intestinal healing, neuropathy, brain function, glycemic control, and athletic performance.   I take TTFD-B1 Max by Maxlife Naturals, Ecological Formulas Allthiamine (TTFD), or Thiamax by EO Nutrition.  Thiamine Tetrahydrofurfuryl Disulfide (TTFD for short) gets into the brain and makes a huge difference with the anxiety and getting the brain off the hamster wheel.  Especially when taken with Magnesium Threonate.   Any form of Thiamine needs Magnesium to make life sustaining enzymes and energy.  I like NeuroMag by Life Extension.  It contains Magnesium Threonate, a form of magnesium that easily crosses the blood brain barrier.  My brain felt like it gave a huge sigh of relief and relaxed when I started taking this and still makes a difference daily.   Other brands of supplements i like are Now Foods, Amazing Formulas, Doctor's Best, Nature's Way, Best Naturals, Thorne, EO Nutrition. Naturewise.  But I do read the ingredients labels all the time just to be sure they are gluten and dairy free. Glad to help with further questions.  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.