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Do Symptons Go Through Cycles?


kristionii

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kristionii Rookie

HI,

I had a positive transglutamine blood test back in May, and I finally had my endoscopy 9 days ago. My doctor commented that "everything looked really good and normal" when he went in, but the actual biopsy will confirm if I have Celiacs. Maybe I'm still in the early stages and now showing significant villi damage? After trying to get the biopsy results for a couple days, I found out he's on vacation for 3 more weeks! So I have no answers until then (although I know from all the members on the board telling me previously that positive blood test = celiacs).

I am still eating gluten until I get the final biopsy results (JUST IN CASE the results are inconclusive or he wants something else done). The last week or two I've noticed my symptoms have been non-existant and/or much better. My eating of certain foods has not changed. Sometimes I have had to run to the bathroom after eating a small bowl of pasta, or a sandwich. These last few weeks I've noticed a signifcant decrease in running to the bathroom, gas, etc. Do symptoms go through cycles? Is it possible to have a few good weeks and/or some bad weeks?

Last question: Is nausea a symptom of Celiacs? I had a peanut butter sandwich (with 2 pieces of whole wheat bread) and felt very nauseated afterwards, and I've had nausea after eating pita bread or other similar things. I wonder if I'm just overeating, or if its a symptom? Otherwise this week, I've been eating movie theatre nachos and restaurant pasta, without out the slightest stomach reaction. What is a gluten-challenge and would it be beneficial in this situation?

Sorry for the long-winded question ... I tend to overanalzye! Which is why waiting 3 more weeks for the biopsy results is torture for me!

Thank you :)

K


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ksymonds84 Enthusiast

Nausea is definately a symptom of being glutened for me. Sometimes accidently being glutened will show up in a couple of hours and sometimes not till the next day. A gluten challenge is going without gluten (for me 2 months) then challenging it by eating gluten to see what your reaction would be. If I were you, I would have the biopsy first and if shows negative then try a gluten challenge. If you stop eating gluten now, you could have a false negative on your biopsy. If you are positive then no challenge will be necessary. If you were having severe gluten reactions then by all means I would stop torturing yourself but since your reactions are lessoning it would make more sense to hang in there for the biopsy. Good luck and keep us posted!

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    • trents
      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      This article, and the comments below it, may be helpful:    
    • Scott Adams
      That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people with celiac or DH don’t react every time they’re exposed, so lack of symptoms doesn’t rule it out. Given your history and family cancer risk, this is something I’d strongly discuss with a celiac-experienced gastroenterologist or dermatologist before attempting a challenge on your own, so risks and benefits are clearly weighed.
    • Greymo
      https://celiac.org/glutenexposuremarkers/    yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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