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irish daveyboy

Coeliac Disease Associated With Psoriasis

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Medscape 7th May 2010

Psoriasis is a chronic inflammatory disorder of the skin reported to be associated with systemic comorbidities.

Although celiac disease is characterized by the presence of antitransglutaminase autoantibodies and intestinal villous damage, it is not limited to the digestive tract, but is rather a multisystemic disorder associated with skin manifestations, endocrine disorders, iron deficiency anaemia, osteoporosis, hypertransaminasaemia, neurological disorders and cancer.

celiac disease shares some common characteristics with typical autoimmune disease including shared autoimmunity, multiorgan involvement, familial aggregation with other autoimmune disorders, complex immunogenetics, production of disease-specific autoantibodies and a strong association with specific HLA haplotypes


Patients with psoriasis have a greater prevalence of celiac disease than matched controls.

Recent studies showed a possibility of undiagnosed celiac disease among patients with psoriasis.

Therefore, physicians treating patients with psoriasis should be aware of this possible association.

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Best Regards,


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