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Asacol Interfere With Gluten Test?


newgfcali

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newgfcali Rookie

OK, so here's the deal.

About 8 months ago I found an association between peripheral neuropathy, the bane of my existence, and gluten sensitivity. I cut out gluten for 4 months, then found Enterolabs. Did the test and, even though I'd been gluten-free for 4 months at the time, it came back positive for gluten sensitivity with a double DQ1. The tTG and malabsorbtion were negative. While I was off gluten my D mostly resolved, although the neuropathy didn't improve perceptively.

Fast forward 2 months. D returned big time. Felt horrible again. Threw up my hands in disgust and saw GI doctor. He ran battery of tests including colonoscopy with biopsy for microscopic colitis. Yep - it's positive. So he put me on Asacol. But here's the tricky part. He doesn't believe the positive lab from Enterolab and wants me to do a gluten challenge and take anti-gliadin IGG and IGA blood test. The challenge is ongoing with the Asacol now.

My question: will the Asacol mess up the gluten test? Has anyone had any experience with this? I don't want to be wasting my time on the challenge if it's going to be compromised by the drug.

The good news is the Asacol seems to be getting the D under control again. Yay!


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Judyin Philly Enthusiast

HI

After almost 5 1/2 yrs gluten-free moved to CA and Dr looked at old tests for cleiac panel, said didn't have it

still 99% gluten-free but now microscopic colitis too

Am on Asacol 4 pills 3 times a day

then ulcer in stomach and positive for H-Pylori

so

the 2 weeks of a 3 drug therapy gave me C-Dif

on vancomycin for 10 days and hoping it gets rid of it

now.......about the drug and gluten challange.

Don't know about an interaction but I'd sure be leary of doing a challange

I f you feel better off gluten..........let your body tell you what to do

Since I've been off c.com for so long, not sure how to get up dates from the link

Good luck in getting better

Judy

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  • Posts

    • trents
      Unfortunately, the development of celiac disease usually is not an end in and of itself. It usually brings along friends, given time. It is at heart an immune system dysfunction which often embraces other immune system dysfunctions as time goes on.
    • Celiacpartner
      Thanks so much for the responses. I will urge him to go for further investigation. To be 48yrs old and develop a new allergy.. ugh, As if celiac disease isn’t enough! 
    • trents
      This does not seem to be an anaphylactic response but I agree it would be wise to seek allergy-food sensitivity testing. You might look into ALCAT food sensitivity testing.
    • Rogol72
      @Celiacpartner, I agree with Scott. We have a food festival yearly in the town I live in, with artisan food stalls everywhere. I spoke to the owner of one of the artisan burger stalls, enquiring if the burgers were gluten-free when I said I was Coeliac ... he said he had a serious anaphylactic allergy to fish himself. He possibly carries an epi-pen or two everywhere he goes. I would go see an allergist as soon as possible as suggested.
    • Scott Adams
      After years of stable management, developing new symptoms to historically safe foods like nuts and fish strongly suggests a secondary issue has developed. It is highly unlikely to be a new gluten issue if the foods themselves are certified gluten-free. The most probable explanations are a new, separate food intolerance (perhaps to a specific protein in certain nuts or fish) or a true IgE-mediated food allergy, which can develop at any age. The symptoms you describe—cramps and the urge to vomit—can be consistent with either. It is crucial he sees an allergist for proper testing (like a skin prick or blood test) to identify the specific culprit and rule out a serious allergy, as reactions can sometimes worsen with repeated exposure.
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