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Help With Test Results


s9421

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s9421 Newbie

Below are my results from my celiac blood test. The report says that the results do not support a diagnosis of celiac disease. I am wondering if I could be borderline, or possibly have a sensitivity to gluten or something similar. I had genetics testing through 23 and Me and I do have the gene that is associated with celiac. I also have a gene that is associated with a significant risk of being IgA deficient, which I have heard can cause false negatives. Please let me know what you think. Thanks!

Deamidated Gliadin Peptide Antibody, IgG (DGP IgG)

Value: .5 EU/ml

Reference Range: <1.3 EU/ml

Deamidated Gliadin Peptide Antibody, IgA (DGP IgA)

Value: 1.4 EU/ml

Reference Range: <2.9 EU/ml

Anti-Human Tissue Transglutaminase IgA ELISA (TTG IgA)

Value: .8 EU/ml

Reference Range: <10.3 EU/ml

Anti-endomysial IgA IFA (EMA IgA)

Negative

Total Serum IgA by Nephelometry (Total IgA)

Value: 124 mg/dl

Reference Range: 44 - 441 mg/dl


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s9421 Newbie

As a follow up, has anyone had negative blood work, but a positive biopsy?

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    • knitty kitty
      You're right, doctors usually only test Vitamin D and B12.  Both are really important, but they're not good indicators of deficiencies in the other B vitamins.  Our bodies are able to store Vitamin B12 and Vitamin D in the liver for up to a year or longer.  The other B vitamins can only be stored for much shorter periods of time.  Pyridoxine B 6 can be stored for several months, but the others only a month or two at the longest.  Thiamine stores can be depleted in as little as three days.  There's no correlation between B12 levels and the other B vitamins' levels.  Blood tests can't measure the amount of vitamins stored inside cells where they are used.  There's disagreement as to what optimal vitamin levels are.  The Recommended Daily Allowance is based on the minimum daily amount needed to prevent disease set back in the forties when people ate a totally different diet and gruesome experiments were done on people.  Folate  requirements had to be updated in the nineties after spina bifida increased and synthetic folic acid was mandated to be added to grain products.  Vitamin D requirements have been updated only in the past few years.   Doctors aren't required to take as many hours of nutritional education as in the past.  They're educated in learning institutions funded by pharmaceutical corporations.  Natural substances like vitamins can't be patented, so there's more money to be made prescribing pharmaceuticals than vitamins.   Also, look into the Autoimmune Protocol Diet, developed by Dr. Sarah Ballantyne, a Celiac herself.  Her book The Paleo Approach has been most helpful to me.  You're very welcome.  I'm glad I can help you around some stumbling blocks while on this journey.    Keep me posted on your progress!  Best wishes! P.S.  interesting reading: Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/
    • NanceK
      So interesting that you stated you had sub clinical vitamin deficiencies. When I was first diagnosed with celiac disease (silent), the vitamin levels my doctor did test for were mostly within normal range (lower end) with the exception of vitamin D. I believe he tested D, B12, magnesium, and iron.  I wondered how it was possible that I had celiac disease without being deficient in everything!  I’m wondering now if I have subclinical vitamin deficiencies as well, because even though I remain gluten free, I struggle with insomnia, low energy, body aches, etc.  It’s truly frustrating when you stay true to the gluten-free diet, yet feel fatigued most days. I’ll definitely try the B-complex, and the Benfotiamine again, and will keep you posted. Thanks once again!
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      Wheat in cow feed would not equal gluten in the milk, @Wheatwacked, please back up extraordinary claims like this with some scientific backing, as I've never heard that cow's milk could contain gluten due to what the cow eats.
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