Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Help With Interpreting 3 Y.o. Results

Pedrose

Recommended Posts

Pedrose Newbie
Pedrose
Posted

Hi. I am a newbie but everyone on this forum seems so friendly I thought I would ask for help. My 3 y.o. son (a non-identical twin) has always had GI issues. The paediatrician ran a series of tests and has diagnosed my son as coeliac off the back of these. I refused a biopsy and she said "I believe it would come back positive anyway." I am after a second opinion on his results because we are moving soon and it could take weeks to find a new Paed.

Coeliac Serology:

Gliadin IgA Abs 3 U/mL

tTG IgA/IgG *41 U/mL

Coeliac Disease: HLA DR & DQ Association

Genotype susceptible for coeliac disease detected. Heterozygous for the .... haploytype, which is consisten with the DQ2 phenotype.

I also wonder about having my other 3 kids tested, especially my 5 year old who is extremely skinny and has had behavioural problems since the age of 18 months.

Thanks I will really value your input.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


sa1937 Community Regular
sa1937
Posted

Pedrose, sorry you haven't gotten a response to your message yet. Did your dr. run a complete celiac panel or are those two results the only things? If so, it's incomplete. Plus you need to give reference ranges for those readings as they vary from lab to lab.

Personally I'm not knowledgeable of gene testing but they're in no way diagnostic for celiac. And children are difficult to diagnose.

Hopefully someone will chime in to give you a better understanding but I wanted to at least give you a response to your post.

Pedrose Newbie
Pedrose
Posted
  • Author

Thanks Sylvia. The only tests the Dr ran were coeliac serology (results listed above), HLA DR & DQ Association (results listed above), a faeces examination, and faecal occult blood which was negative. What other tests make up the full panel? I am really confused now and looking forward to finding a new paediatrician when we move. I do not know the labs markers as patients are not privy to that information. I am in Australia if this makes any difference.

mushroom Proficient
mushroom
Posted

Thanks Sylvia. The only tests the Dr ran were coeliac serology (results listed above), HLA DR & DQ Association (results listed above), a faeces examination, and faecal occult blood which was negative. What other tests make up the full panel? I am really confused now and looking forward to finding a new paediatrician when we move. I do not know the labs markers as patients are not privy to that information. I am in Australia if this makes any difference.

You should ask for copies of all test results on all tests for all your family. The results slip will have the ranges that the lab uses when they run the tests. Copies can be important later when going to other doctors, and also to check that they have not been overlooked or misread. Being in Australia shouldn't make any difference. I am in New Zealand and always get copies of alll test results. I was at a hospital clinic yesterday and they were impressed with the information I was able to provide them. The complete celiac panel is:

Anti-Gliadin (AGA) IgA

Anti-Gliadin (AGA) IgG

Anti-Endomysial (EMA) IgA

Anti-Tissue Transglutaminase (tTG) IgA

Deamidated Gliadin Peptide (DGP) IgA and IgG

Total Serum IgA

It is important to run the total serum IgA because if this is below normal it can invalidate the other IgA tests. The DGP is considered to be the most sensitive test for celiac, particularly in children. Read about the work of Dr. Rodney Ford in Christchurch.

ETA: Hold off on your other children until you can verify what is happening with this one - that will provide a good basis for making a decision.

Pedrose Newbie
Pedrose
Posted
  • Author

Thanks Mushroom. I will cut and paste that list onto my pc. I have looked at the serolgy results again and there are numbers in brackets that I am wondering if they are the normal range. It reads

Gliadin IgA Abs 3 U/mL (0-20)

tTG IgA/IgG *41 U/mL (0-24)

I definitely do not have the peptide one or the total serology one.

Pedrose Newbie
Pedrose
Posted
  • Author

Update: my son has been gluten-free for two weeks and did his first normal coloured, firm poo ever today. He even did it on the toilet and not in his pants which is a major breakthrough. My husband and I went gluten-free with my son. Last Wednesday I ate gluten at a funeral in the belief that I am not coeliac but the next day I had two major bouts of diarrhoea. I am now gluten-free again not wishing to go through that again. My husband says his stools are starting to firm up too. Even though I still don't understand my son's tests, experience is telling me that a gluten-free diet is working.

mushroom Proficient
mushroom
Posted

I keyed a response to you the other day, but it obviously did not post. Yes, the numbers you posted were the normal ranges. Anything outside those ranges would be considered positive. I am glad your son is responding to the diet and doing well and that you have decided on a gluten-free household. When a child has celiac he got it from at least one parent (and sometimes both - which it sounds like could be the case with your family). It is amazing the number of people who discover they are gluten sensitive once they stop eating it. My hub went gluten free with me (figured it couldn't hurt -- his mom had MS :blink: ) and then he started cheating a little bit here and there with beer and sourdough french bread. Not only did his D return, but he also developed dermatitis herpetiformis to confirm the diagnosis :o

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


carecare Enthusiast
carecare
Posted

So the tTG was 41 correct when the normal range is (0 - 24). If that is how I am reading it then that would indicate celiac, I believe.

Good luck and glad to hear you guys are seeing positive results on the diet. After going gluten free in the household because my son's blood test was on the positive side I realized I had problems with gluten as well. Now my sister who went gluten free ...doing the paleo diet lifestyle change to loose weight and get healthy gets really ill when ingesting gluten too. I have a sister with pretty severe probably MS who still won't give the diet a chance...which saddens me..and her husband has psoriasis and now arthritic psoriasis...but he too won't give it a try. I'm glad you all see there is a difference for yourselves as well. Here's to getting all getting healthY! B)

Pedrose Newbie
Pedrose
Posted
  • Author

Thank you Mushroom and Carecare. Initially I was in a bit of denial because I lost confidence in my Pediatrician after she greeted me with "How's the gluten free diet going?" and I had to reply "You haven't given me the results yet." Tests done in July and follow-up appointment was October. Furthermore, she wouldn't give me a referral letter or results to take to new doctor (we are moving interstate) so I went and got them from my GP. There is no way I would go to a new doctor empty handed. Anyway, I am now facing up to the challenge and have the attitude that the diet is totally manageable so long as I am prepared. Being a vegetarian I am already used to restricted choices, thankfully. Now just to help the kids adjust!

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,144
    • Most Online (within 30 mins)
      7,748
    Jenny0384
    Newest Member
    Jenny0384
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Headaches / Migraines and Hypoglycaemia

      By trents · Posted

      My migraines generally have their onset during the early morning hours as well. Presently, I am under siege with them, having headaches all but two days so far this month. I have looked at all the things reported to be common triggers (foods, sleep patterns, weather patterns, stress, etc.). Every time I think I start to see a pattern it proves not to pan out in the long run. I'm not sure it's any one thing but may, instead, be a combination of things that coalesce at certain times. It's very frustrating. The medication (sumatriptan or "Imatrix") is effective and is the only thing that will quell the pain. NSAIDs, Tylenol, even hydrocodone doesn't touch it. But they only give you 9 does of sumatriptan a month. And it doesn't help that medical science doesn't really know what causes migraines. They know some things about it but the root cause is still a mystery.
    • Scott Adams
      Tamale ingredients

      By Scott Adams · Posted

      These are labeled gluten-free: https://www.amazon.com/Corn-Husks-Tamales-Authentic-Flavorful/dp/B01MDSHUTM/
    • Wheatwacked
      GI DX celiac despite neg serology and no biopsy

      By Wheatwacked · Posted

      Just a gluten free diet is not enough.  Now you have to identify and replenish your malnutrition.  Celiac disease is co-morbid with malabsorption syndrome.  Low vitamin D, Low Thiamine caused Gastointeston Beriberi, low choline, low iodine are common the general population, and in newly diagnosed Celiacs in the western culture its is more likely.  It takes time to heal and you need to focus on vitamins and minerals.  Gluten free foods are not fortified like regular processed foods.  
    • Sarah Grace
      Headaches / Migraines and Hypoglycaemia

      By Sarah Grace · Posted

      Dear Kitty Since March I have been following your recommendations regarding vitamins to assist with various issues that I have been experiencing.  To recap, I am aged 68 and was late diagnosed with Celiac about 12 years ago.  I had been experiencing terrible early morning headaches which I had self diagnosed as hypoglycaemia.  I also mentioned that I had issues with insomnia, vertigo and brain fog.   It's now one year since I started on the Benfotiamine 600 mg/day.  I am still experiencing the hypoglycaemia and it's not really possible to say for sure whether the Benfotiamine is helpful.  In March this year, I added B-Complex Thiamine Hydrochloride and Magnesium L-Threonate on a daily basis, and I am now confident to report that the insomnia and vertigo and brain fog have all improved!!  So, very many thanks for your very helpful advice. I am now less confident that the early morning headaches are caused by hypoglycaemia, as even foods with a zero a GI rating (cheese, nuts, etc) can cause really server headaches, which sometimes require migraine medication in order to get rid off.  If you are able to suggest any other treatment I would definitely give it a try, as these headaches are a terrible burden.  Doctors in the UK have very limited knowledge concerning dietary issues, and I do not know how to get reliable advice from them. Best regards,
    • knitty kitty
      High DGP-A with normal IGA

      By knitty kitty · Posted

      @rei.b,  I understand how frustrating starting a new way of eating can be.  I tried all sorts of gluten-free processed foods and just kept feeling worse.  My health didn't improve until I started the low histamine AIP diet.  It makes a big difference.   Gluten fits into opioid receptors in our bodies.  So, removing gluten can cause withdrawal symptoms and reveals the underlying discomfort.  SIBO can cause digestive symptoms.  SIBO can prevent vitamins from being absorbed by the intestines.  Thiamine insufficiency causes Gastrointestinal Beriberi (bloating, abdominal pain, nausea, diarrhea or constipation).  Thiamine is the B vitamin that runs out first because it can only be stored for two weeks.  We need more thiamine when we're sick or under emotional stress.  Gastric Beriberi is under recognised by doctors.  An Erythrocyte Transketolace Activity test is more accurate than a blood test for thiamine deficiency, but the best way to see if you're low in thiamine is to take it and look for health improvement.  Don't take Thiamine Mononitrate because the body can't utilize it well.  Try Benfotiamine.  Thiamine is water soluble, nontoxic and safe even at high doses.  I thought it was crazy, too, but simple vitamins and minerals are important.  The eight B vitamins work together, so a B Complex, Benfotiamine,  magnesium and Vitamin D really helped get my body to start healing, along with the AIP diet.  Once you heal, you add foods back in, so the AIP diet is worth doing for a few months. I do hope you'll consider the AIP diet and Benfotiamine.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.