Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

This Is Just Confusing (Iga, Ttg, Iga Deamidated)

eborzecki

Recommended Posts

eborzecki Explorer
eborzecki
Posted

I just got written lab results and I am confused, I thought I had this all straighten out :(

Beginning of November

Gliadin antibody IGA 56 HIGH (cut off 18)

TTG antibody 111.6 Positive <20

I then went on a two week diet and doctor told me to repeat these tests in a different lab

End of November

Anti deamidated Gliadin Iga 258 HIGH (cut off 20)

TTG antibody 68 Positive <20

So I was all scared and really no explanation of why my TTG went down and my IGA went up, now I am more confused because I don't know what the difference is between these tests, and what does it mean when I have all three positive :(

Please help

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ravenwoodglass Mentor
ravenwoodglass
Posted

I just got written lab results and I am confused, I thought I had this all straighten out :(

Beginning of November

Gliadin antibody IGA 56 HIGH (cut off 18)

TTG antibody 111.6 Positive <20

I then went on a two week diet and doctor told me to repeat these tests in a different lab

End of November

Anti deamidated Gliadin Iga 258 HIGH (cut off 20)

TTG antibody 68 Positive <20

So I was all scared and really no explanation of why my TTG went down and my IGA went up, now I am more confused because I don't know what the difference is between these tests, and what does it mean when I have all three positive :(

Please help

The deamidated Gliadin is a different test from the gliadin and is more sensitive than the gliadin IGA. With two weeks on the diet is isn't unusual for the TTG to be lower than before you went gluten free. What it means is you are celiac and you are doing the right thing by staying gluten free and you may want to retest in 6 months or so and make sure the levels are going down.

Roda Rising Star
Roda
Posted

You had three different tests for celiac with all being positive. The deamidated gliadin and tTG are pretty specific for celiac. Just looking at the blood work alone you have celiac. Some doctors will diagnose just on that alone, but there are some who still want a scope/biopsy to confirm.

My youngest son has celiac and went gluten free last year with just positive blood work. I did have the scope/biopsy done on my oldest son because his bloodwork has always came back really negative, despite having symptoms of celiac/gluten intolerence. His scope was negative also, but he went gluten free afterwards anyway. It has been 3.5 months and he is doing well and I am seeing improvements.

Skylark Collaborator
Skylark
Posted

What ravenwood said, plus the results are from two different dignostic labs so they may not be comparable.

mushroom Proficient
mushroom
Posted

All three positive means there is absolutely no doubt that you are celiac. Lower tTG score on a gluten free diet means that gluten free is what you need to be. The diet is working!! As the others have said, your IgA did not go up because the Deamidated Gliadin is a different test which has different ranges.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,195
    • Most Online (within 30 mins)
      7,748
    Marrianne Kraatz
    Newest Member
    Marrianne Kraatz
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Does Dailymed.nlm.nih.gov site have filters for gluten?

      By Scott Adams · Posted

      Clearly from what you've said the info on Dailymed is much more up to date than the other site, which hasn't been updated since 2017. The fact that some companies might be repackaging drugs does not mean the info on the ingredients is not correct.
    • RMJ
      Waiting Gastroenterology review

      By RMJ · Posted

      To evaluate the TTG antibody result we’d need to know the normal range for that lab.  Labs don’t all use the same units.  However, based on any normal ranges that I’ve seen and the listed result being greater than a number rather than a specific number, I’d say yes, that is high! Higher than the range where the test can give a quantitative result. You got good advice not to change your diet yet.  If you went gluten free your intestines would start to heal, confusing any further testing,
    • Bev in Milw
      Does Dailymed.nlm.nih.gov site have filters for gluten?

      By Bev in Milw · Posted

      Scott is correct….Thank you for catching that!      Direct link for info  of fillers.    http://www.glutenfreedrugs.com/Excipients.htm Link is on 2nd page  of www.glutenfreedrugs.com   Site was started by a pharmacist (or 2) maybe 15-20 yrs ago with LAST updated in  2017.  This makes it’s Drug List so old that it’s no longer relevant. Companies & contacts, along with suppliers &  sources would need to be referenced, same amount effort  as starting with current data on DailyMed      That being said, Excipient List is still be relevant since major changes to product labeling occurred prior ’17.           List is the dictionary that sources the ‘foreign-to-us’ terms used on pharmaceutical labels, terms we need to rule out gluten.    Note on DailyMed INFO— When you look for a specific drug on DailyMed, notice that nearly all of companies (brands/labels) are flagged as a ‘Repackager’… This would seem to suggest the actual ‘pills’ are being mass produced by a limited number of wholesaler suppliers (esp for older meds out of  patent protection.).      If so, multiple repackager-get  bulk shipments  from same supplier will all  be selling identical meds —same formula/fillers. Others repackager-could be switching suppliers  frequently based on cost, or runs both gluten-free & non- items on same lines.  No way to know  without contacting company.     While some I know have  searched pharmacies chasing a specific brand, long-term  solution is to find (or teach) pharmacy staff who’s willing help.    When I got 1st Rx ~8 years ago, I went to Walgreens & said I needed gluten-free.  Walked  out when pharmacist said  ‘How am I supposed  to know…’  (ar least he as honest… ). Walmart pharmacists down the block were ‘No problem!’—Once, they wouldn’t release my Rx, still waiting on gluten-free status from a new supplier. Re: Timeliness of DailyMed info?   A serendipitous conversation with cousin in Mi was unexpectedly reassuring.  She works in office of Perrigo, major products of OTC meds (was 1st to add gluten-free labels).  I TOTALLY lucked out when I asked about her job: “TODAY I trained a new full-time employee to make entries to Daily Med.’  Task had grown to hours a day, time she needed for tasks that couldn’t be delegated….We can only hope majorities of companies are as  conscientious!   For the Newbies…. SOLE  purpose of  fillers (possible gluten) in meds is to  hold the active ingredients together in a doseable form.  Drugs  given by injection or as IV are always gluten-free!  (Sometimes drs can do antibiotics w/ one-time injection rather than 7-10 days of  pills .) Liquid meds (typically for kids)—still read labels, but  could be an a simpler option for some products…
    • Ginger38
      Food Allergies

      By Ginger38 · Posted

      So I recently had allergy testing for IGE antibodies in response to foods. My test results came back positive to corn, white potatoes, egg whites. Tomatoes, almonds and peanuts to name a few.  I have had obvious reactions to a few of these - particularly tomatoes and corn- both GI issues. I don’t really understand all this allergy versus celiac stuff. If the food allergies are mild do I have to avoid these foods entirely? I don’t know what I will eat if I can’t  have corn based gluten free products 
    • JForman
      7yo struggling!

      By JForman · Posted

      We have four children (7-14 yo), and our 7 year old was diagnosed with NCGS (though all Celiac labs were positive, her scope at 4 years old was negative so docs in the US won't call it celiac). We have started her on a Gluten Free diet after 3 years of major digestive issues and ruling out just about everything under the sun. Our home and kitchen and myself are all gluten-free. But I have not asked my husband/her dad or her other siblings to go completely gluten-free with us. They are at home, but not out of the home. This has led to situations when we are eating out where she has to consistently see others eating things she can't have and she has begun to say "Well, I can't have <fill in the blank>...stupid gluten."  How have you supported your gluten-free kiddos in the mental health space of this journey, especially young ones like her. I know it's hard for me as an adult sometimes to miss out, so I can't imagine being 7 and dealing with it! Any tips or ideas to help with this? 
×
×
  • Create New...