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Russ H

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Russ H last won the day on April 18

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  1. There is a predictive model for children on this link. Depends on sex, HLA genes and number of affected close relatives. The model only goes up to age 12 so it would be interesting to know what the lifetime risk is. https://hputter.shinyapps.io/preventcd/
  2. The problem with a a multiple screening test like this is that it is likely to generate at least one result that is outside the normal range in a healthy person leading to futile investigations. The pathogenesis of dermatitis herpetiformis makes it unlikely that someone would have raised IgA-tTG3 but not raised IgA-tTG2. Suspected dermatitis herpetiformis...
  3. There is a good paper here on causes of seronegative villous blunting. The most common is seronegative coeliac disease. Not All That Flattens Villi Is Celiac Disease: A Review of Enteropathies
  4. Sorry but I have to dash for an appointment so little time just now. Your signs and symptoms and response to a gluten-free diet sound like seronegative coeliac disease. Seronegative coeliac disease, Coeliac UK.
  5. ohmichael, do you know that you've reacted to gluten? We all get ups and downs in health - a mild viral infection one week and maybe an unset stomach another time. It is easy to ascribe the symptoms to gluten exposure even when that is not the cause of the symptoms. I would wait and see if it happens again before giving up your job, especially if you don...
  6. People with coeliac disease tend to have lower systolic blood pressure. However symptoms vary greatly between people and there are multiple cases in the literature of hypertension in people diagnosed with coeliac disease that gradually reverses on a strict gluten-free diet.
  7. There is not enough information to assess the likelihood of coeliac disease. You'll have to chase this up with the quack. The lab should provide antibody titres and a reference range. They might just have done an EMA test, which is negative/positive and antiquated - a proper IgA-ttG2 test would be more helpful.
  8. I developed a heart arrhythmia and on several occasions had to wear a 24 hour Holter monitor. Among other things, I had premature atrial complexes (PACs) and occasional AFib. I was very fit at the time, running and cycling. This completely disappeared following my diagnosis and following a strict gluten free diet. I haven't had a single episode since, in...
  9. I have read research indicating differing reactions to various oat cultivars, however, nothing suggesting that some contain gluten - do you have a source for that?
  10. That's the thing - about 1% of the population have coeliac disease: if it were 10%, the social burden would be so high that gluten would be removed from general consumption.
  11. Hi Cosyfeyre and welcome to the forum. Hashimoto's thyroiditis can cause moderately raised levels of tissue transglutaminase antibodies (as can other autoimmune and inflammatory conditions). This could explain the weak positive shown for tTG IgG. It is certainly worth following up. Some people can react to gluten without having coeliac disease, and many...
  12. It can take between 6 months and 2 years for the dermatitis herpetiformis rash to resolve. The symptoms of dermatitis herpetiformis arise from deposits of certain antibodies building up in the skin. These deposits attract immune cells leading to inflammation and blistering. It can take 10 years for the deposits to be reabsorbed although symptoms resolve long...
  13. Your initial test showed a moderately raised level of IgA tTG2. There are several causes of this apart from coeliac disease including: inflammation of the joints, bowel and liver. Transient rise in levels can be caused by an infection.
  14. Small amounts of gliadin are detectable in some samples of human breast milk but these are at too low a level to cause symptoms. No gliadin has been detected in the beef of grain-fed cattle. https://pmc.ncbi.nlm.nih.gov/articles/PMC5622696/
  15. I doubt very much that it contains any gluten. It works by producing an artificial blood clot, mixing 2 or more proteins found in the natural blood clotting cascade. These are refined from human blood donations. It comes in 2 vials that are mixed immediately before use and clot quickly.
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