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Test Results Are In.....


Tasha2004

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Tasha2004 Contributor

I guess the only positive test I still have is the Gliadin IgA. My doctor says it's not a big deal until the Ttg turns positive, but that it could be latent Celiac.

I'm still wondering if anyone has any advice on high IgA and what to do with the info. Mine was 74 normal is 25 or less.........


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lisa922 Apprentice

Hi! I am in the process of trying to figure out my results also. My ttg was negative and my Iga was only 24, but I had some other numbers that were higher. My small intestine biopsy does show damaged villi. Today I spoke with a very knowledgable nurse at a gi office - she told me that if the ttg is positive, even with a normal Iga, Celiac should be investigated as a possibility. She did seem puzzled that my ttg was normal (or actually negative) and said that there is a genetic test that can be done I'm not sure how this is supposed to be written, but she said to ask for HLAeq2 and HLAdq8 tests. If they are both negative, then it is not Celiac. If one is positive and one is negative, you still have a 30% chance of not getting Celiac. I am going to post this info and see if anyone else is familiar with it and I'm going to request the test because I want to make sure I am following the right treatment. She said there are many other conditions that can damage your villi. Good luck with your results!

LISA

Tasha2004 Contributor

Thanks Lisa. I'm still doing research on this. I wish I could afford my own tests but I just cant right now.

You were brave enough for the biopsy, I havent chosen to do one yet.

Do you have symptoms?

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    • trents
      Possibly. Your total IGA (Immunoglobulin A, Qn, Serum) is actually high so you are not IGA deficient. In the absence of IGA deficiency, the most reliable celiac antibody test would be the t-Transglutaminase (tTG) IgA for which your score is within normal range. There are other things besides celiac disease that might cause an elevated DGP-IGA (Deamidated Gliadin Abs, lgA) for which you do have a positive score. It might also be of concern that your total IGA is elevated as that can indicate some other health problems, some of which are serious.  Had you been practicing a gluten free or a reduced gluten free diet prior to the blood draw? Talk to your physician about these things. I would also seek an endoscopy/biopsy of the small bowel to check for damage to the villous lining, which is the gold standard diagnostic test for celiac disease.
    • MicG
      Test results as follows: Deamidated Gliadin Abs, lgA 40 H (normal range 0-19) Deamidated Gliadin Abs, IgG 4 (0-19) t-Transglutaminase (tTG) IgA <2 (0-3) t-Transglutaminase (tTG) IgG <2 (0-5) Endomysial Antibody IgA Negative (Negative) Immunoglobulin A, Qn, Serum 535 H (87-352) Do I have celiac?
    • catnapt
      how long does it take for the genetic blood test for celiac to come back? I saw the GI today, she was great. She says I def have an issue with gluten and that my symptoms align more with celiac disease than NCGS, so she's doing the genetic testing, Ordered a test for SIBO but said that's just to cover all bases, she doesn't think I have that. If the blood work comes back negative for the genes, then I will cancel the endoscopy. If positive, I will try the 2 week gluten challenge and get the endoscopy done. If I can't manage the gluten challenge (I had HORRIBLE symptoms last time and quit after 12 days) then we'll just assume it's celiac disease and go from there. She says she does a full nutrient panel on all her pts every year, that was nice to hear.I'm on so many supplements it would be nice to only have to get the ones I truly need! so yeh, really anxious about the test results for the genes!! I have an identical twin sister so I'd need to tell her if it's positive, she'd prob want to get tested too. *interesting note: when I said if the blood work comes back that I don't have the genes, then I'm in the clear - she said, well,,,,,,not necessarily. But she didn't want to go into as we had a lot to go over. I did make a  mental note of that comment and will ask her when I see her next time.   she was very thorough! I was impressed! she even checked- up on some lab work I had done that my Endo ordered. I like her, I am looking forward to seeing her again. I think I'll get some good advice and info from her she also complimented me on my diet.   said it was a very gut friendly and healthy diet 
    • Scott Adams
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    • Russ H
      This sounds like a GP who is ignorant regarding coeliac disease. The risk with consuming gluten for several days is that it triggers the coeliac immune response, leading to raised auto-antibodies and active disease for several months. People may not even be aware of symptoms during this process, but it is causing damage to the body. As trents has said, the gut lining normally recovers on a strict gluten-free diet, and this happens much faster in children than in adults.
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