No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Enzyme and Sulfur Oxidization Deficiencies in Autistic Children with Known Food/Chemical Intolerance

The following was taken from AUTISM 95:

The following was written about a study: to determine whether children with autism and known food/chemical intolerance have a deficiency of phenol-sulphotransferase-P enzyme and/or a low capacity to oxidize sulfur compounds. On the results obtained so far, all 18 children have a low enzyme level, and some have a low capacity to oxidize sulfur compounds. This enzyme metabolizes phenols and amines. Therefore, with a reduced level, these children will be unable to fully metabolize foods and chemicals which contain phenols (and amines)...

Ads by Google:

...The majority of children in this category ... have allergy to or intolerance of many foods/chemicals, the main offenders being wheat, cows milk, and salicylates. Their family histories show asthma, eczema, migraines, hay fever, plus many other allergy-related conditions...Their siblings display learning difficulties, dyslexia, etc.....

In autism and other disorders we suspect a peptidase deficiency so that proteins are not broken down into individual amino acids and these short, biologically active chains (peptides) exist in appreciable quantities. Even in the normal gut there will be some of these substances but they are not normally a problem. If the gut wall is leaky (celiac disease or lack of sulfur transferase, etc) these compounds will get into the bloodstream. Even then there should be no serious problem unless they enter the blood...

...The brain is protected by the blood brain barrier (BBB) which is partly physical and partly chemical in nature. Thus this would keep peptides out unless there are huge quantities circulating.

So when the intestinal wall is not healthy and the brain is vulnerable, the brain is affected directly. Learning disabilities, behavioral problems, and even extremes such as schizophrenic behavior can result. The three things which happen are:

  • Not Enough Enzymes To Fully Digest Particular Protein Chains
  • A Breachable Intestinal Wall
  • A Vulnerable Brain

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Both sets are made on shared lines. That was the point of my response. Many people have gotten sick from Gluten free products from Frito Lay.

Welcome! I can not answer your question, but genetic testing is used as a last resource for ruling OUT celiac disease. Normally, while on a gluten diet, a person is tested for antibodies (just like you can test antibodies (different ones) for lupus, thyroid or type 1 diabetes (blood test)....

Ravenwood may be on to something there. Check out the Mayo clinic link for more info on Raynauds syndrome. Raynaud's Syndrome is another autoimmune condition as is celiac disease. https://www.mayoclinic.org/diseases-conditions/raynauds-disease/symptoms-causes/syc-20363571 Raynaud's (r...

Yes, the second half of the list are possibly made on shared machinery. The ones labeled gluten free are not. And they are tested for Gluten.

Can you get a copy of your bloodwork and the results and ranges so we can tell what has already been run? We have some folks really knowledgable about lab work that might be able to give some insight or let you know what other tests to have your doctor run. I agree with Ennis that this should be...