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Could Egg Yolks Hold the Key to Celiac Disease Treatment?

Celiac.com 08/12/2015 - There are numerous pills, enzymes, and other products in development that are all designed to provide moderate protection against accidental gluten exposure to people with celiac disease to gluten-intolerance.

Photo: CC--Neil ConwayCan a new pill, which uses egg yolk antibodies to coat gluten, allowing it to pass from the body without harm, find a place on the crowded roster of contenders?

Driven by a desire to provide relief for people with celiac disease, Hoon Sunwoo, an associate professor of pharmaceutical sciences, has spent the last 10 years working on the proprietary pill.

If Hoon has his way, people with celiac disease may soon be able to enjoy bread, pasta and other gluten products without suffering headaches, digestion problems and severe intestinal damage that come with the adverse gluten reactions of celiac disease.

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The pill works by using egg yolk antibodies to coat the gluten and allow it to pass from the body without doing any damage. While not a cure, Sunwoo's pill, now under development at the University of Alberta, may allow those people to join friends for a beer and pizza.

Sunwoo makes it very clear that his pill is not a cure or long-term treatment solution, and the people with the disease should still follow a strict gluten-free diet.

The pill is designed to be eaten by a person with celiac disease five minutes before eating or drinking, and would provide protection from an adverse gluten reaction for the next one or two hours.

The pill completed safety clinical trials two months ago and is expected to begin efficacy clinical trials next year.

Read more at CBC.CA.

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3 Responses:

 
R Hodge
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
17 Aug 2015 7:57:07 AM PDT
Won't do this celiac patient any good, because I am also allergic to egg yolk.

 
Dawna
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
18 Aug 2015 8:56:42 AM PDT
Heck if it helps I'm all for it.

 
sc'Que?
Rating: ratingfullratingfullratingemptyratingemptyratingempty Unrated
said this on
19 Aug 2015 2:49:24 AM PDT
Sounds more like a "travel abroad" plan than a realistic one for daily use. Still... if it keeps the research plowing forward...




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The only symptom I know of that is celiac for certain is dh, which must be diagnosed by a dermatologist.

I have both eoe and celiac and now that I have been gluten free for 18 months, my anemia is gone. It is good to get off the iron supliments because mine may have been the cause of my ulcers. It feels good to recover and heal! I may work my way down to fewer supliments and lots of feel great da...

Your daughter does not have a strong positive. I suspect that the GI might do as RMJ suggested which would be to load her up on gluten for six months and retest. On the other hand, with a diagnosed sibling and a very mild positive, your GI might recommend the endoscopy or run the test again to ...

I was diagnosed with celiac last year on an endoscopy looking for the cause of my anemia. At the time, my GI doc tested m for EoE and it was negative. Fast forward 11 months, I developed sudden heart burn, dysphagia out of the blue. My doc thinks it's EoE. Biopsy was last week and I am still wait...

No, the control test is to verify that she will react to that particular type of test. If she didn't, then certain of the bloods would not be applicable to her. They would be false negatives. As far as tests being weak positives, that's like being a little pregnant. A positive is a positive....