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Do We Have More Celiac Disease Because Fewer Children Are Dying?

What's the relationship Between Child Mortality Rates and Prevalence of celiac disease?


Does less infant death mean more adults with celiac disease? Photo: CC--Kicki Zeilon

Celiac.com 08/15/2017 - Some evidence indicates that rates of celiac disease in the general population are increasing over time.

Prior to the discovery of gluten's role in celiac disease, the prognosis for celiac sufferers was bleak. Did higher betas of death keep celiac disease rates correspondingly lower?

To provide an answer, a team of researchers set out to examine a possible relationship between mortality rates for children under five, and prevalence rates of celiac disease. The research team included Federico Biagi; Alberto Raiteri; Annalisa Schiepatti; Catherine Klersy; and Gino R. Corazza.

Their team conducted a review of literature, and found 27 studies done in 17 different countries between 1995 and 2011 describing rates of celiac disease in schoolchildren. Four of the studies were conducted in Italy.

Their meta-analysis compared prevalence rates between specific-country under-five mortality groups, publication year and age.

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In recent decades, mortality rates for under-five year olds have been decreasing all over the world. This reduction is paralleled by rising rates of celiac disease. The Spearman correlation coefficient for these terms was -63%, 95%CI -82% to -33% (p < 0.001).

So, the higher the mortality rate, the lower the prevalence of celiac disease. This finding is confirmed by the meta-analysis of the 4 studies conducted in Italy over time.

The mortality rate for under five-year-olds seems to influence the rate of celiac disease in the general population.

They predict a rise, in the near future, of the number of celiac disease patients, due to better survival rates of celiac children.

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Interesting article. I do wonder how she was 'misdiagnosed' though and how she came to the conclusion she wasn't celiac.

Try dropping the oats for while and see if that helps. Some of us, myself included, react to even the ones that are certified as gluten free.

Hey guys, I appreciate the input, you are all very sweet and kind. I do not eat out at all. Only eat food I cook. No alcohol. Only certified gluten-free oats, grains, rice, etc. I have 3 roommates in a little house. I have my own gluten-free section to cook and prepare foo...

What was your gluten free diet like? I wonder if, when you were gluten-free, you went more whole food, less processed food? Or did you continue to eat processed food that was just gluten free? One reason I ask is that I have cut way back on grains and processed foods like gluten-free bread, but o...

Equal parts Hershey Coco Powder and a sweetener with a pinch of salt. Super easy to make your own. I like adding a bit to my coffee with almond milk, and lakanto sugar free maple, or a bit of monk fruit or stevia. PS you might want to drop dairy milk. The enzymes to break it down come from th...