A Breath Test for Celiac Disease? Yes Please!

How can it treat celiac when tx for celiac disease is a gluten-free diet?

I have been diagnosed with Celiac with an endoscopy testing.  There is no cure ! It’s diet! 

First- by making it easier and less invasive to test for Celiac or diabetes- it will  lead to more diagnoses of Celiac - that can then be treated.  And It sounds like they could use it to help check compliance and healing of Celiac.  It doesn’t say it replaces a gluten-free diet or insulin in a diabetic.  

45 minutes ago, kareng said:

First- by making it easier and less invasive to test for Celiac or diabetes- it will  lead to more diagnoses of Celiac - that can then be treated.  And It sounds like they could use it to help check compliance and healing of Celiac.  It doesn’t say it replaces a gluten-free diet or insulin in a diabetic.  

Aren't the antibody tests more specific for Celiac? What would this test add to them?

No needles or blood draw would be the only advantage.

The breath test would be done to diagnose not treat according to the article above I am curious however ,whether it could diagnose celiac without eating the foods.I am a recently retired nurse and diagnosed with an allergy to gluten not sensitivity by an ENT specialist .It affected my sinuses severely .The bloating only came once i was eating high carbs while I was on a very high dose of oral steroids .I have a picture where I look ready to deliver a child full term.I have one sibling with a wheat allergy another with a gluten sensitivity and as well  2  distant cousins with wheat allergies.My siblings and I were off gluten before we had testing done as things were  too bad to continue eating it

So we have no way of knowing if we all have celiac disease.Here's hoping!

The article does say to diagnose and treat celiac disease.

Quote / "The excitement arrises because a team of scientists has developed a selective, non-invasive breath test that could be used to diagnose and treat celiac disease and Type-II diabetes."  // Unquote

I assume they mean to diagnose and monitor celiac disease though.

Monitoring if a treatment works is part of "the treatment".   If you break your leg, part of "treating" the leg is repeat xrays (to see how its doing in the cast).  By the logic that this one "guest" keeps repeating, then a followup xray to decide to take off the cast is not part of the treatment?

  Seems a silly thing to quibble about if there is an easier way to diagnose any disease.  

Mr. J.A. erred in his explanation of the test---it was developed to detect DPP enzyme activity---NOT DDPi(inhibitor) activity---DPPi is the class of drugs used to treat type2Diabetes---it would seem the main use of this test would be to measure DPP activity AFTER ingestion of DPPi to see if the drug would be effective, since that is how the drug works by inhibiting DPP so it does not inactivate GLP and GIP allowing these hormones to counteract glucagon. I cannot see how it applies to Celiac disease---either diagnostically or therapeutically---in fact the other article referenced which is from 2006--found no difference in intestinal levels of DPP in patients with celiac disease or other malabsorption syndromes---and presumably this is what the breath test is measuring-- intestinal levels of DPP.  There also was no difference in serum levels of DPP among the Celiacs, the MAS, and controls    Interestingly most of the OTC so called "digestive enzymes" which claim to digest gluten and advertised to help people with problems with gluten( but with the disclaimer--"NOT INTENDED TO TREAT CELIAC DISEASE"-since that would make it a drug and subject to FDA regulations instead of a "SUPPLEMENT" which is unregulated----most of these contain DPP as their active ingredient---DPP=dipeptidyl protenase---an enzyme that can digest proteins like gluten--------  unfortunately when subjected to legitimate scientific testing DPP does NOT effectively digest gliadin peptides which initiate celiac disease--so such products are of no help to celiacs.  Maybe after further work other applications of this test will become clearer 

As an addendum to my prior comments above, I went back and read the entire article describing this test---I am not at all sure how well versed in celiac disease the authors are----they state that DPP has recently been implicated in the pathogenesis of celiac disease!------the 2 references they give #s 27 and 28 are from 1990 and 1994---we have certainly found out a great deal about the pathogenesis of celiac disease since then and it has nothing to do with DPP! Then seemingly in support of their test they refer to the same article(#29) from 2006 that was referenced by JA at the end of his article reporting on the test---which as I already stated above did NOT seem to find DPP levels helpful.   The one area where I can see it may potentially be helpful would be in a patient with KNOWN celiac disease after being on a GFD for 1-2yrs to check for DPP levels---if WNL it would indicate mucosal recovery----you would need to get a baseline when first diagnosed and then the repeat later to see if the DPP had recovered---this would be in place of repeating the SB biopsy.  It would seem to me this would still require much work to see if such measurements accurately correlate with mucosal recovery.