Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Why Can't I Understand This Genetic Testing?

Lilpig99

Recommended Posts

Lilpig99 Newbie
Lilpig99
Posted

First post and trying to figure out what the genetic results mean:

Alpha 3:01, 5

Beta 3:01, 3:02

This test was HLA typing for Celiac and was done at Mayo. Still waiting for doc appt to understand the results.

Results show "permissive" for celiac and also "celiac pairs present", but I'd like to understand the numbers. Nowhere does it say HLA dq2 or HLA dq8. And these don't seem to read like other results.

Btw...my guy has a horrid amount of food allergies, eosinophilic esophagitis and duodenitis. Currently undertaking major elimination diet and repeat endoscopes. First scope showed normal villous architecture and no lymphocyte infiltration. This test was throwing the net wide to find out what's going on with vomitting etc. We had regular blood testing done for celiac but he was already on the elimination diet and not eating wheat ...so I still don't know why we did that bloodwork--it all came back zero for antibodies. Lol

Thanks for helping my make sense of the numbers...

:)))

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


SMRI Collaborator
SMRI
Posted

Mayo reports their gene testing a bit strange and I still can't understand mine :D.  What were his numbers from his Celiac tests?

Lilpig99 Newbie
Lilpig99
Posted
  • Author

Here's the entire lineup:

DQ Alpha1 03:01, 05

----------------------------------------

DQ Beta1 03:01, 03:02

Serologic Equivalent: 7,8

----------------------------------------

Celia Gene Pairs Present? Yes

These genes are permissive for celiac. .....

Tissue Transglutaminase IGA 0

Gliadin IGA Antibody 0

Immunoglobulin A (IGA) Celiac 95 (range 21-291)

(Wheat IgE 3.15 Class 2)

I'm usually just fine with medical stuff but yes, Mayo's HLA typing is hard for me to understand.:(

SMRI Collaborator
SMRI
Posted

Did they run more than that?  From what these are saying, he is not Celiac, unless he is Celiac and these are follow up tests after being gluten free, which then means this is good.  The IgA that is 95 is a total IgA and they run that to make sure that is in the normal range.  Generally they run a total IgG as well.  I've never been able to get a straight answer on the gene testing here so not sure if someone will help or not.  When I asked my GI, he wasn't even sure how to read them...well, the GI intern I talked to :D. 

 

Gluten is found in more than just wheat so he may or may not have been exposed to Gluten at the time of the testing.  What was/is he eating typically at that time and how long had he been off wheat?  

 

I don't know about the Wheat IgE #s if that is normal, high, low, etc.  Did they run any other Ig anything tests?

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,163
    • Most Online (within 30 mins)
      7,748
    Estee
    Newest Member
    Estee
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Who's Online (See full list)

  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • DAR girl
      Celiac and allergic to common subs and adds in prepared foods

      By DAR girl · Posted

      Looking for help sourcing gluten-free products that do not contain potato or corn derived ingredients. I have other autoimmune conditions (Psoriatic Arthritis and Sjogrens) so I’m looking for prepared foods as I have fatigue and cannot devote a lot of time to baking my own treats. 
    • Scott Adams
      Disregarded

      By Scott Adams · Posted

      I am so sorry you're going through this. It's completely understandable to feel frustrated, stressed, and disregarded after such a long and difficult health journey. It's exhausting to constantly advocate for yourself, especially when you're dealing with so many symptoms and positive diagnoses like SIBO, while still feeling unwell. The fact that you have been diligently following the diet without relief is a clear sign that something else is going on, and your doctors should be investigating other causes or complications, not dismissing your very real suffering. 
    • Oldturdle
      Paying for my own Celiac screening at WalkInLab so a positive result doesn’t become part of my medical history

      By Oldturdle · Posted

      It is just so sad that health care in the United States has come to this.  Health insurance should be available to everyone, not just the healthy or the rich.  My heart goes out to you.  I would not hesitate to have the test and pay for it myself.  My big concern would be how you could keep the results truly private.  I am sure that ultimately, you could not.  A.I. is getting more and more pervasive, and all data is available somewhere.  I don't know if you could give a fake name, or pay for your test with cash.  I certainly would not disclose any positive results on a private insurance application.  As I understand it, for an official diagnosis, an MD needs to review your labs and make the call.  If you end up in the ER, or some other situation, just request a gluten free diet, and say it is because you feel better when you don't eat gluten.      Hang in there, though.  Medicare is not that far away for you, and it will remove a lot of stress from your health care concerns.  You will even be able to "come out of the closet" about being Celiac!
    • plumbago
      Paying for my own Celiac screening at WalkInLab so a positive result doesn’t become part of my medical history

      By plumbago · Posted

      Yes, I've posted a few times about two companies: Request a Test and Ulta Labs. Also, pretty much we can all request any test we want (with the possible exception of the N protein Covid test and I'm sure a couple of others) with Lab Corp (or Pixel by Lab Corp) and Quest. I much prefer Lab Corp for their professionalism, ease of service and having it together administratively, at least in DC. And just so you know, Request a Test uses Lab Corp and Quest anyway, while Ulta Labs uses only Quest. Ulta Labs is cheaper than Request a Test, but I am tired of dealing with Quest, so I don't use them so much.
    • Scott Adams
      Does Dailymed.nlm.nih.gov site have filters for gluten?

      By Scott Adams · Posted

      PS - I think you meant this site, but I don't believe it has been updated in years: http://glutenfreedrugs.com/ so it is best to use: You can search this site for prescriptions medications, but will need to know the manufacturer/maker if there is more than one, especially if you use a generic version of the medication: To see the ingredients you will need to click on the correct version of the medication and maker in the results, then scroll down to "Ingredients and Appearance" and click it, and then look at "Inactive Ingredients," as any gluten ingredients would likely appear there, rather than in the Active Ingredients area. https://dailymed.nlm.nih.gov/dailymed/   
×
×
  • Create New...