Questions about DGP testing

[Renaye]

Back in 2011, I had a Prometheus test run which consisted of a +DGP IgG, +DGP IgA, -TTG IgA, -EMA IgA, Total IgA was normal.  My gastro did a genetics test which was unable to interpret but started me on a gluten-free diet and sent me to a rhuemmy doctor.  A later biopsy was negative.  Now that doctor is gone and my new doctor which I like, does not think much of my results. He believes there needed to be more to the panel - IGG maybe? which is better than the DGP.  I tried to explain to him that the DGP was the newer more accurate tests but I didn't get through to him.  Is there some tests missing from the panel that was taken?  Am I wrong?  I am starting to believe that gastro doctors are only good for prescribing drugs and doing procedures and bloodwork.  My health and nutrition is mainly in my hands and base on my ability to identify problems and follow through with them.   Very frustrated.

[cyclinglady]

He wants to order the TTG IgA after you have been gluten free for years (that's the only missing celiac disease test)  and you are not IgA deficient?  A positive is a positive.  When you get one on the panel, the doctor is to move forward and obtain biopsies via endoscopy.  Hopefully, he managed to get four to six samples as it is really easy to miss damaged areas (sounds like this happened to you).  Did you keep a copy of the biopsy report? 

You sounds like me.  I just tested positive to ONLY the DGP IgA.  The rest of the panel was negative.  My biopsies  revealed a Marsh Stage IIIB (moderate to severe damage).  When I was glutened last July, new provider and insurance only allows PCP's to order the TTG IgA and the deficiency test.  Guess what?  I tested negative.  I had to get to a new GI to get the DGP's which again, only the DGP IgA was positive confirming that I really has been glutened!  

I assume you are doing well on the gluten-free diet or have have new or your old symptoms come back?  Why the follow-up with the new GI?  

 

 

[Renaye]

I did not get a final biopsy report but the last one was taken in 2013 and my discharge papers indicate scalloped mucosa in duodenum and duodenal mucosal changes consistent with celiac disease.  This was 2 years after going gluten free. Biopsies were taken and nurse called that they were negative.  Yes, I am doing fine on the diet but did not have typical symptoms. My rhuemmy doctor believes that my sicca symptoms are in remission due to the diet.  I see a gastro doctor yearly due to obtaining a prescription referral for dexilant and monitoring for possible barrett's. Going for egd late in April.  Thanks for your reply.