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Celiac Panel Results


lovetoeat

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lovetoeat Rookie

I received my Celiac Panel results and they were as follows:

Tissutrans IgA 3

Gliadin IGG AB 29 (this one came back high)

Gliadin IGA AB 5

Should I be concerned about these numbers?

Also, everytime I eat, it goes right through me! I have had my gallbladder checked and it is fine.

Thanks,


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zip2play Apprentice

Did your doctor think the numbers called for a biopsy?

lovetoeat Rookie

Yes, yesterday after I saw him and told him my other symptoms. Is that okay?

tarnalberry Community Regular
I received my Celiac Panel results and they were as follows:

Tissutrans IgA 3

Gliadin IGG AB 29 (this one came back high)

Gliadin IGA AB 5

Should I be concerned about these numbers?

Also, everytime I eat, it goes right through me! I have had my gallbladder checked and it is fine.

Thanks,

I'm suspicious that both the IgA's game back low. He should have taken a total IgA to tell if those two tests were useful or not. Good luck with the biopsy! (Though you'll have to keep eating gluten for it. :-( )

KaitiUSA Enthusiast

I ditto Tiffany.

The total serum IgA needs to be done because that rules out IgA deficiency and if you have IgA deficiency then those tests were not accurate.

lovetoeat Rookie

What is the total IgA? I thought I had that done??? who knows..all these tests are confusing :P

I have to have a colonscopy and an endoscopy on Tuesday :wacko:

Will my doc be able to tell right away if I have celiac disease?

Thanks :)

tarnalberry Community Regular

Total IgA is a measure of the total IgA antibodies in your blood stream. It helps determine if you're IgA deficient. Here's an analogy to explain why it's important:

Someone asks you if you want a drink, you say yes, they say how much of the glass you want filled. Well... if you don't know how big the glass is, you don't know what to tell them. If you say "half full", but it's a shot glass, you've got very little drink!

If you're IgA deficient, you don't have much at all in your body, so a lower than normal anti-gliandin IgA (which is specific for gliandin) doesn't mean much because your "glass" (your normal amount) is already much lower than normal.


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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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