Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

My son's tests results - confused!

Heather G

Recommended Posts

Heather G Newbie
Heather G
Posted

Hello!  Hoping I can get some input regarding my 11 year old son's test results.  Primary care doc said the results may indicate celiac, but pediatrician that he sent us to said he was happy with the results and that my son was definitely not celiac.  After the research I have done, I was shocked at that response.  He also said that no gastroenterologist would biopsy based on these results.  I would greatly appreciate any advice!

Ttg Iga - 12.9 (0.0 - 19.9 normal)

Dgp Iga - <5.2 (0.0 - 19.9 normal)

Dgp Igg - 82.8 (0.0 - 19.9 normal)

My son has fatigue, joint pains, difficulty putting on weight.  Initial blood tests indicated low iron and elevated liver enzymes (which led me to request celiac screen).  

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


tessa25 Rising Star
tessa25
Posted

Wow! Not a doc, but if 82 (extremely high) does not indicate celiac they wouldn't use it for celiac testing. Send a copy of these results to a gastroenterologist so they can either diagnose based on that or do an endoscopy before your son goes gluten free.  I don't understand why the primary sent you to a pediatrition instead of a gastro after seeing those results. At least now you know what pediatrition to avoid. Lol

 

cyclinglady Grand Master
cyclinglady
Posted

Welcome.  

I can see the hesitation since just the DGP Igg is positive.  It is not a common result.  Was he tested for an IgA deficiency?  That test, when in conjunction with the celiac tests,  is used as a control test (to see if any IgA tests are working properly).  If the IgA deficiency were negative it could explain the low results on the other tests.  Perhaps you left it off your posting?  

In any case, a positive is a positive and a GI referral is the next step.  I can tell you that my CD test result was a positive on ONLY on the DGP IgA, yet my biopsies revealed moderate to severe damage.  

Open Original Shared Link

Is it possible to get into a GI?  Go back to your PCP and not the Ped?  

Heather G Newbie
Heather G
Posted
  • Author

Thank you both for your replies, I appreciate your insight.  The total serum Iga test was not done - I requested that we do it, but the pediatrician said it was unnecessary (will not be  seeing him again!).  Our next step will be a GI -our primary care doc was hesitant to go that route as we do not have a pediatric GI in province.  I will request to see a regular GI.

I find it interesting that the lab ranges are so different for acceptable ttg Iga levels.  The Mayo Clinic positive is >10 u/ml where as our Canadian lab positive is >19.9 u/ml.  My son is at 12.9.

cyclinglady Grand Master
cyclinglady
Posted

With the control test (in this case the IgA deficiency test), you do not know if the TTG IgA or the DGP IgA results are even valid.  It is a necessary part of the celiac testing process.  You could also request the EMA IgA test as well.  

Different labs have different ranges, so I would dismiss the Mayo lab ranges.  

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,742
    • Most Online (within 30 mins)
      7,748
    MistyMoon
    Newest Member
    MistyMoon
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Who's Online (See full list)

    • There are no registered users currently online
  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Theresa2407
      How Come Gluten Didnt Bother Me In Italy

      By Theresa2407 · Posted

      Maybe you have a low  intolerance to Wheat.   Rye, Barley and Malt are the gluten in Celiac disease.  It has always been stated Wheat and Gluten, not just a Wheat intolerance.  Barley will keep me in bed for (2) weeks.  Gut, Migrains, Brain fog, Diahrea.  It is miserable.  And when I was a toddler the doctor would give me a malt medicine because I always had Anemia and did not grow.  Boy was he off.  But at that time the US didn't know anyone about Celiac.  This was the 1940s and 50s.  I had my first episode at 9 months and did not get a diagnosis until I was 50.  My immune system was so shot before being diagnoised, so now I live with the consequences of it. I was so upset when Manufacturers didn't want to label their products so they added barley to the product.  It was mostly the cereal industry.  3 of my favorite cereals were excluded because of this. Malt gives me a bad Gut reaction.
    • Gigi2025
      How Come Gluten Didnt Bother Me In Italy

      By Gigi2025 · Posted

      Thanks much Scott.  Well said, and heeded.   I don't have Celiac, which is fortunate.
    • Scott Adams
      Possible celiac - need advice

      By Scott Adams · Posted

      Do you have the results of your endoscopy? Did you do a celiac disease blood panel before that?  Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:    
    • Scott Adams
      Celiac or not??

      By Scott Adams · Posted

      It is odd that your Tissue Transglutaminase (TTG) IgA level has bounced from the "inconclusive" range (7.9, 9.8) down to a negative level (5.3), only to climb back up near the positive threshold. This inconsistency, coupled with your ongoing symptoms of malabsorption and specific nutrient deficiencies, is a strong clinical indicator that warrants a more thorough investigation than a simple "satisfactory" sign-off. A negative blood test does not definitively rule out celiac disease, especially with such variable numbers and a classic symptomatic picture. You are absolutely right to seek a second opinion and push for a referral to a gastroenterologist. A biopsy remains the gold standard for a reason, and advocating for one is the most direct path to getting the answers you need to finally address the root cause of your suffering. Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:    
    • Scott Adams
      How Come Gluten Didnt Bother Me In Italy

      By Scott Adams · Posted

      There is a distinction between gluten itself and the other chemicals and processing methods involved in modern food production. Your experience in Italy and Greece, contrasted with your reactions in the U.S., provides powerful anecdotal evidence that the problem, for some people, may not be the wheat, but the additives like potassium bromate and the industrial processing it undergoes here. The point about bromines displacing iodine and disrupting thyroid function is a significant one, explaining a potential biological mechanism for why such additives could cause systemic health issues that mimic gluten sensitivity. It's both alarming and insightful to consider that the very "watchdog" agencies meant to protect us are allowing practices banned in many other developed countries. Seeking out European flour and your caution about the high-carb, potentially diabeticgenic nature of many gluten-free products are excellent practical takeaways from your research, but I just want to mention--if you have celiac disease you need to avoid all wheat, including all wheat and gluten in Europe.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.