Mixed test results

[Tbymommy]

Hi.

My ten year old was ordered the celiac testing, along with other tests, due to lack of growth. Within the celiac blood panel some tests came back negative and some positive. 

The deiamidated giadin test came back positive but the other tests came back negative. He is being referr d to a GI for a biopsy. 

Can he have celiac with only one positive and is it likely he does? There is a wait time for the biopsy so I'm sitting and waiting to see anxiously!

 

 

[cyclinglady]

2 hours ago, Tbymommy said:

Hi.

My ten year old was ordered the celiac testing, along with other tests, due to lack of growth. Within the celiac blood panel some tests came back negative and some positive. 

The deiamidated giadin test came back positive but the other tests came back negative. He is being referr d to a GI for a biopsy. 

Can he have celiac with only one positive and is it likely he does? There is a wait time for the biopsy so I'm sitting and waiting to see anxiously!

 

 

Welcome!  I am sorry that your son is ill!   Yes, you can have celiac disease with only one positive in the panel.  That happened to me.  I had only a positive on just the DGP IgA.  It was not a fluke.  I test this way even in follow-up testing.  Biopsies revealed intestinal damage ☹️.  

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This kind of result does happen among the very young or very old (and some people in between).  While not common, it is possible.  You need to see a GI.  For some it can be a while.  In that case, keep checking for appointment cancellations.  

Before an endoscopy he must be consuming a gluten diet for 2 to 4 weeks prior.  I would hate for a kid to have to wait.  Again, see what you can do to expedit the appointment.  

In the meantime, learn all you can about celiac disease.  Anyone else with autoimmune disease in your family?  They should consider testing too.  

[Tbymommy]

So I have another son with a different autoimmune disorder (jia). But my brother has type one diabetes which I've read is gene related to celiac. I myself have been tested for celiac twice because I have gastro issues with it but it has always been negative. 

Yes they said it may be while. Hoping it's not too long!

[cyclinglady]

You should confirm that you were given the entire celiac panel.  It is still common for most doctors to use the screening TTG and then check for an IgA deficiency (cheap, effective but does not catch all celiacs) .    What if you test like your child?  What if you are a seronegative celiac (occurs in 10% of celiacs)?